How much do paid clinical trials in Lancaster pay?

Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.

Are clinical trials in Lancaster safe?

Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.

How do I join a study in Lancaster, PA?

Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.

Is compensation for clinical trials taxable?

In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.

Can I be in more than one clinical trial at a time?

Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Lancaster typically complete one or two studies per year.

Paid Clinical Trials Lancaster, PA — 436 Studies Recruiting (Jul 2026)

Use of Nicotine Pouches Among Daily Smokers

Tobacco Dependence N/A Interventional 375 participants sought

Penn State College of Medicine — Hershey, Pennsylvania (25.0 mi) · Sponsor: Milton S. Hershey Medical Center

See eligibility & contact on ClinicalTrials.gov (NCT06043362)

Transitional Care Program for Fluid Overload in Cirrhosis

Cirrhosis, Liver N/A Interventional 20 participants sought

Penn State Milton S. Hershey Medical Center — Hershey, Pennsylvania (25.0 mi) · Sponsor: Milton S. Hershey Medical Center

See eligibility & contact on ClinicalTrials.gov (NCT06174272)

St. Joseph's HPV Self-sampling: Offering a Self-sampling Option in Clinic

Cervical Cancer Screening N/A Interventional 50 participants sought

Penn State Health St. Joseph's — Reading, Pennsylvania (28.3 mi) · Sponsor: Milton S. Hershey Medical Center

See eligibility & contact on ClinicalTrials.gov (NCT05092022)

ENdoluminal LIGHT ActivatED Treatment of Upper Tract Urothelial Cancer (ENLIGHTED) Study

Transitional Cell Cancer of Renal Pelvis and Ureter Phase 3 Interventional 100 participants sought

The Pennsylvania State University (Penn State) Milton S. Hershey Medical Center — Hershey, Pennsylvania (25.0 mi) · Sponsor: Steba Biotech S.A.

See eligibility & contact on ClinicalTrials.gov (NCT04620239)

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Recurrent Head and Neck Squamous Cell Carcinoma, Recurrent Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 188 participants sought

UPMC Memorial — York, Pennsylvania (23.2 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT04671667)

Maintenance Obinutuzumab in Treating Patients With Central Nervous System Lymphoma Who Have Achieved a Complete or Partial Response

Primary Central Nervous System Lymphoma Phase 2 Interventional 28 participants sought

Pennsylvania State University — Hershey, Pennsylvania (25.0 mi) · Sponsor: Providence Health & Services

See eligibility & contact on ClinicalTrials.gov (NCT06175000)

Clinical Evaluation of Precision for the Potassium and Ionized Calcium Tests in Capillary Specimens

Hematologic Tests N/A Interventional 425 participants sought

Penn State Health Milton S. Hershey Medical Center (Hershey) — Hershey, Pennsylvania (25.0 mi) · Sponsor: Abbott Point of Care

See eligibility & contact on ClinicalTrials.gov (NCT07287631)

A Study to Assess the Safety and Efficacy of Different Doses of ELV001 to Treat Active Rheumatoid Arthritis in Patients With an Inadequate Response to Methotrexate and Tumor Necrosis Factor Inhibition (START SYNERGY)

Active Rheumatoid Arthritis Phase 2 Interventional 180 participants sought

Pennsylvania Regional Center for Arthritis & Osteoporosis Research — Wyomissing, Pennsylvania (26.6 mi) · Sponsor: Elevara Medicines Limited

See eligibility & contact on ClinicalTrials.gov (NCT07409103)

STOP-HAE: A Phase 3 Study of ADX-324 in HAE

Hereditary Angioedema, HAE Phase 3 Interventional 90 participants sought

ADARx Clinical Site — Hershey, Pennsylvania (25.0 mi) · Sponsor: ADARx Pharmaceuticals, Inc.

See eligibility & contact on ClinicalTrials.gov (NCT06960213)

Optimizing Tracheal Intubation Outcomes and Neonatal Safety

Infant, Intubation Complication N/A Interventional 3,000 participants sought

Penn State Milton S. Hershey Medical Center — Hershey, Pennsylvania (25.0 mi) · Sponsor: Children's Hospital of Philadelphia

See eligibility & contact on ClinicalTrials.gov (NCT05838690)

Impact of a Diabetes Education Mobile Web Application on Patients With Uncontrolled Type 2 Diabetes

Diabetes Mellitus, Type 2, Diabetes Education N/A Interventional 65 participants sought

Reading Hospital, an affiliate of Tower Health — West Reading, Pennsylvania (27.5 mi) · Sponsor: The Reading Hospital and Medical Center

See eligibility & contact on ClinicalTrials.gov (NCT05893927)

Stroke Thrombectomy and Aneurysm Registry

Stroke, Thromboses, Intracranial N/A Observational 40,000 participants sought

WellSpan York Hospital — York, Pennsylvania (23.2 mi) · Sponsor: Medical University of South Carolina

See eligibility & contact on ClinicalTrials.gov (NCT04994756)

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

Plasma Cell Myeloma, RISS Stage I Plasma Cell Myeloma Phase 3 Interventional 1,450 participants sought

Penn State Milton S Hershey Medical Center — Hershey, Pennsylvania (25.0 mi) · Sponsor: ECOG-ACRIN Cancer Research Group

See eligibility & contact on ClinicalTrials.gov (NCT04566328)

Impact of Parental Emotion Regulation on the Treatment of ADHD

ADHD N/A Interventional 65 participants sought

Penn State Health Dept of Psychiatry — Hershey, Pennsylvania (25.0 mi) · Sponsor: Milton S. Hershey Medical Center

See eligibility & contact on ClinicalTrials.gov (NCT05299814)

Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of Age

Amblyopia Phase 3 Interventional 252 participants sought

Conestoga Eye — Lancaster, Pennsylvania (0.4 mi) · Sponsor: Jaeb Center for Health Research

See eligibility & contact on ClinicalTrials.gov (NCT06524882)

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Phase 2 Interventional 2,000 participants sought

Penn State Milton S Hershey Medical Center — Hershey, Pennsylvania (25.0 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT05564390)

Optimizing Pain Treatment in Children On Mechanical Ventilation

Mechanical Ventilation, Pediatric Acute Respiratory Failure Phase 3 Interventional 644 participants sought

Penn State Health/Hershey Medical Center — Hershey, Pennsylvania (25.0 mi) · Sponsor: Weill Medical College of Cornell University

See eligibility & contact on ClinicalTrials.gov (NCT06994442)

A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer

Prostatic Neoplasms, Castration-Resistant Phase 3 Interventional 800 participants sought

Penn State Milton S. Hershey Medical Center — Hershey, Pennsylvania (25.0 mi) · Sponsor: Janssen Research & Development, LLC

See eligibility & contact on ClinicalTrials.gov (NCT07225946)

A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer Phase 2 Interventional 150 participants sought

Cancer Care Associates Of York /ID# 270971 — York, Pennsylvania (23.2 mi) · Sponsor: AbbVie

See eligibility & contact on ClinicalTrials.gov (NCT06568939)

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Breast Cancer, Early Breast Cancer Phase 3 Interventional 4,300 participants sought

Research Site — Reading, Pennsylvania (28.3 mi) · Sponsor: AstraZeneca

See eligibility & contact on ClinicalTrials.gov (NCT05774951)

Fusion or Cognitive Ultrasound-guided Biopsy to Detect Prostate Cancer

Prostate Cancer, Diagnosis N/A Interventional 1,306 participants sought

Pennsylvania State University — Hershey, Pennsylvania (25.0 mi) · Sponsor: Albany Medical College

See eligibility & contact on ClinicalTrials.gov (NCT06517901)

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma, Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7 Phase 2, Phase 3 Interventional 613 participants sought

Penn State Milton S Hershey Medical Center — Hershey, Pennsylvania (25.0 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT01810913)

iLookOut Micro-learning to Improve Knowledge Retention

Knowledge, Attitudes N/A Interventional 12,000 participants sought

Penn State College of Medicine — Hershey, Pennsylvania (25.0 mi) · Sponsor: Milton S. Hershey Medical Center

See eligibility & contact on ClinicalTrials.gov (NCT06273618)

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Ovarian Carcinoma N/A Interventional 1,956 participants sought

Lancaster General Ann B Barshinger Cancer Institute — Lancaster, Pennsylvania (0.4 mi) · Sponsor: NRG Oncology

See eligibility & contact on ClinicalTrials.gov (NCT04251052)

A Trial to Evaluate Intravesical Nadofaragene Firadenovec Alone or in Combination With Chemotherapy or Immunotherapy in Participants With High-grade BCG Unresponsive Non-muscle Invasive Bladder Cancer

Non-muscle Invasive Bladder Cancer With Carcinoma in Situ Phase 3 Interventional 250 participants sought

Keystone Urology Specialists — Lancaster, Pennsylvania (0.4 mi) · Sponsor: Ferring Pharmaceuticals

See eligibility & contact on ClinicalTrials.gov (NCT06545955)

Paid Clinical Trials in Lancaster, PA

Studies recruiting near Lancaster right now