Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/PA/Pittsburgh
Updated July 2026 from ClinicalTrials.gov

Paid Clinical Trials in Pittsburgh, PA

Studies commonly pay $75 to $4,500 per completed study

1,236 clinical trials are currently recruiting participants within 30 miles of Pittsburgh. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

1,236studies recruiting
9+research centers nearby
4condition categories
Live from the NIH registry

Studies recruiting near Pittsburgh right now

Top 25 of 1,236 recruiting studies, sorted by proximity — each links to its official registry page

Pupil-Indexed Noninvasive Neuromodulation

Paresis N/A Interventional 110 participants sought
VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: VA Office of Research and Development
See eligibility & contact on ClinicalTrials.gov (NCT06282406)

QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 in HER2-low Metastatic Breast Cancer

HER2-positive Metastatic Breast Cancer N/A Observational 200 participants sought
University of Pittsburgh Medical Center — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: Abramson Cancer Center at Penn Medicine
See eligibility & contact on ClinicalTrials.gov (NCT06551116)

Study of Sodium Phenylbutyrate (ACER-001) for the Treatment of Pediatric and Adults Patients With Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD)

Medium-chain Acyl-CoA Dehydrogenase Deficiency Phase 2 Interventional 24 participants sought
UPMC Children's Hospital of Pittsburgh — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: Jerry Vockley, MD, PhD
See eligibility & contact on ClinicalTrials.gov (NCT06773026)

Zenith® Fenestrated+ Clinical Study

Aortic Aneurysm, Abdominal, Juxtarenal Aortic Aneurysm N/A Interventional 105 participants sought
University of Pittsburgh Medical Center — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: Cook Research Incorporated
See eligibility & contact on ClinicalTrials.gov (NCT04875429)

Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures: A Pragmatic, Randomized Controlled Trial

Tibial Fractures, Pain Phase 3 Interventional 1,000 participants sought
Allegheny General Hospital — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: Major Extremity Trauma Research Consortium
See eligibility & contact on ClinicalTrials.gov (NCT07006675)

A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

Ulcerative Colitis, Crohn's Disease Phase 3 Interventional 240 participants sought
UPMC Children's Hospital of Pittsburgh - Adolescent Medicine (Oakland) - PIN — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: Takeda
See eligibility & contact on ClinicalTrials.gov (NCT05442567)

Sirolimus in Combination With Metronomic Chemotherapy in Children With High-Risk Solid Tumors

Solid Tumor Phase 2 Interventional 55 participants sought
Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center (UPMC) — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: Emory University
See eligibility & contact on ClinicalTrials.gov (NCT04469530)

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Recurrent Head and Neck Squamous Cell Carcinoma, Recurrent Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 188 participants sought
UPMC-Saint Margaret — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04671667)

A Study to Learn About the Study Medicine Called Rimegepant in Adolescents With Frequent Migraine

Migraine Phase 3 Interventional 200 participants sought
UPMC Children's Hospital of Pittsburgh — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT06616194)

CEM to Reduce Biopsy Rates for Less Than Highly Suspicious Breast Abnormalities: a Prospective Study

Breast Cancer Phase 4 Interventional 2,100 participants sought
UPMC Magee-Womens Hospital — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: Margarita Louise Zuley
See eligibility & contact on ClinicalTrials.gov (NCT05206331)

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

Amyloidosis, Amyloid Cardiomyopathy Phase 3 Interventional 587 participants sought
University of Pittsburgh Medical Center, Presbyterian Hospital — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: Eidos Therapeutics, a BridgeBio company
See eligibility & contact on ClinicalTrials.gov (NCT06563895)

Phase 1/2 Study of PYX-201 in Combination With Pembrolizumab in Advanced Solid Tumors

Advanced Solid Tumors Phase 1, Phase 2 Interventional 220 participants sought
University of Pittsburgh Medical Center — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: Pyxis Oncology, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06795412)

Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

Locally Advanced Lung Non-Small Cell Carcinoma, Metastatic Lung Non-Small Cell Carcinoma Phase 1, Phase 2 Interventional 37 participants sought
University of Pittsburgh Cancer Institute (UPCI) — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT07012031)

A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacabtagene- Autoleucel / Zola-cel), CD19-CAR T Cells, Versus Standard of Care in Participants With Active Systemic Sclerosis

Systemic Sclerosis Phase 3 Interventional 92 participants sought
Local Institution - 0143 — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
See eligibility & contact on ClinicalTrials.gov (NCT07335562)

Familial Mediterranean Fever and Related Disorders: Genetics and Disease Characteristics

Familial Mediterranean Fever (FMF), Autoinflammation N/A Observational 5,000 participants sought
University of Pittsburgh — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: National Human Genome Research Institute (NHGRI)
See eligibility & contact on ClinicalTrials.gov (NCT00001373)

Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer

Prostate Cancer Phase 4 Interventional 700 participants sought
Univ of Pittsburgh Medical Center — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: Novartis Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT05803941)

A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis)

Polymyositis, Dermatomyositis Phase 3 Interventional 240 participants sought
Research Site — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06455449)

Active Surveillance in Older Women With ER+ Breast Cancer

Early Stage Estrogen Receptor (ER) Positive Breast Cancer N/A Observational 50 participants sought
University of Pittsburgh Medical Center — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: University of Pittsburgh
See eligibility & contact on ClinicalTrials.gov (NCT07262138)

A Study of DR-01 in Subjects With Large Granular Lymphocytic Leukemia or Cytotoxic Lymphomas

LGLL - Large Granular Lymphocytic Leukemia, Primary Cutaneous Gamma-Delta T-Cell Lymphoma Phase 1, Phase 2 Interventional 200 participants sought
Dren Investigational Site 2 — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: Dren Bio
See eligibility & contact on ClinicalTrials.gov (NCT05475925)

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Ganglioneuroblastoma, Nodular, Neuroblastoma Phase 3 Interventional 478 participants sought
Children's Hospital of Pittsburgh of UPMC — Pittsburgh, Pennsylvania (1.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06172296)
Google-rated

Top-rated research centers in Pittsburgh

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

University of Pittsburgh, Institute for Clinical Research Education (ICRE)

Parkvale Building, 200 Meyran Ave, Pittsburgh, PA 15213

Clinical and Translational Science Institute (CTSI)

★ 5.0
Forbes Tower, Meyran Ave Ste 7057, Pittsburgh, PA 15213
(412) 648-4185
"They helped me when no one else could or would! Thank you CTSI at Pitt, thank you."
— Zachary Ferguson, 5★

University of Pittsburgh Center for Behavioral Health and Smart Technology

Professional Building, 230 McKee Pl #600, Pittsburgh, PA 15213
(412) 692-4758

Physical Therapy-Clinical Research Center

100 Technology Dr, Pittsburgh, PA 15219

Magee-Womens Research Institute

★ 4.4
204 Craft Ave, Pittsburgh, PA 15213
(412) 641-6091
"Wish I could rate zero stars. I had a serious surgery done March 14,2023 and my medical staff neglected to provide me with any discharge meds someone…"
— Lolita 'Lolo' (Lolo), 1★

Alzheimer Disease Research Center

200 Lothrop St, Pittsburgh, PA 15213
(412) 692-2700

UPMC Hillman Cancer Center: Research Pavilion

5115 Centre Ave #2, Pittsburgh, PA 15232

University of Pittsburgh O'Brien Center for Kidney Research

3550 Terrace St, Pittsburgh, PA 15261
(412) 647-3118

University of Pittsburgh Liver Research Center

Biomedical Science Tower, S414, 200 Lothrop St, Pittsburgh, PA 15261
(412) 624-3507

Clinical trials in Pittsburgh: what's recruiting

The Pittsburgh area currently has 1,236 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Pittsburgh, the most active research areas are:

  • Cancer & Oncology12 studies
  • Immune & Skin3 studies
  • Liver & Kidney2 studies
  • Heart & Vascular1 studies

Every listing shows the study phase, the recruiting site and its distance from Pittsburgh, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Pittsburgh

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Pittsburgh participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Pittsburgh?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
How do I join a study in Pittsburgh, PA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in Pittsburgh?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Pittsburgh.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Pittsburgh typically complete one or two studies per year.

Paid clinical trials near Pittsburgh

Other metros within reach

Youngstown, OH89 Canton, OH314 Akron, OH398 Erie, PA91 Cleveland, OH1,419 Hagerstown, MD112 Lorain, OH1,313 Buffalo, NY520

More of PA

Philadelphia2,169 York459 Lancaster436 Harrisburg412 Reading281 Allentown236 Scranton100 Erie91

New paid studies open every week

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