Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/PA/Harrisburg
Updated July 2026 from ClinicalTrials.gov

Paid Clinical Trials in Harrisburg, PA

Studies commonly pay $75 to $4,500 per completed study

412 clinical trials are currently recruiting participants within 30 miles of Harrisburg. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

412studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Harrisburg right now

Top 25 of 412 recruiting studies, sorted by proximity — each links to its official registry page

ENdoluminal LIGHT ActivatED Treatment of Upper Tract Urothelial Cancer (ENLIGHTED) Study

Transitional Cell Cancer of Renal Pelvis and Ureter Phase 3 Interventional 100 participants sought
The Pennsylvania State University (Penn State) Milton S. Hershey Medical Center — Hershey, Pennsylvania (12.4 mi) · Sponsor: Steba Biotech S.A.
See eligibility & contact on ClinicalTrials.gov (NCT04620239)

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Recurrent Head and Neck Squamous Cell Carcinoma, Recurrent Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 188 participants sought
UPMC Memorial — York, Pennsylvania (23.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04671667)

Maintenance Obinutuzumab in Treating Patients With Central Nervous System Lymphoma Who Have Achieved a Complete or Partial Response

Primary Central Nervous System Lymphoma Phase 2 Interventional 28 participants sought
Pennsylvania State University — Hershey, Pennsylvania (12.4 mi) · Sponsor: Providence Health & Services
See eligibility & contact on ClinicalTrials.gov (NCT06175000)

Clinical Evaluation of Precision for the Potassium and Ionized Calcium Tests in Capillary Specimens

Hematologic Tests N/A Interventional 425 participants sought
Penn State Health Milton S. Hershey Medical Center (Hershey) — Hershey, Pennsylvania (12.4 mi) · Sponsor: Abbott Point of Care
See eligibility & contact on ClinicalTrials.gov (NCT07287631)

Optimizing Tracheal Intubation Outcomes and Neonatal Safety

Infant, Intubation Complication N/A Interventional 3,000 participants sought
Penn State Milton S. Hershey Medical Center — Hershey, Pennsylvania (12.4 mi) · Sponsor: Children's Hospital of Philadelphia
See eligibility & contact on ClinicalTrials.gov (NCT05838690)

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

Plasma Cell Myeloma, RISS Stage I Plasma Cell Myeloma Phase 3 Interventional 1,450 participants sought
Penn State Health Medical Group - Andrews Patel Hematology/Oncology East — Harrisburg, Pennsylvania (0.1 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT04566328)

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

Advanced Endometrial Carcinoma, Recurrent Endometrial Carcinoma Phase 3 Interventional 255 participants sought
UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion — Mechanicsburg, Pennsylvania (7.8 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT07198074)

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Phase 2 Interventional 2,000 participants sought
Penn State Milton S Hershey Medical Center — Hershey, Pennsylvania (12.4 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05564390)

A Long Term Extension Study to Evaluate the Safety and Efficacy of Afimkibart (RO7790121) in Participants With Atopic Dermatitis

Atopic Dermatitis Phase 2 Interventional 120 participants sought
Best Skin Research LLC — Camp Hill, Pennsylvania (3.1 mi) · Sponsor: Hoffmann-La Roche
See eligibility & contact on ClinicalTrials.gov (NCT07223697)

Optimizing Pain Treatment in Children On Mechanical Ventilation

Mechanical Ventilation, Pediatric Acute Respiratory Failure Phase 3 Interventional 644 participants sought
Penn State Health/Hershey Medical Center — Hershey, Pennsylvania (12.4 mi) · Sponsor: Weill Medical College of Cornell University
See eligibility & contact on ClinicalTrials.gov (NCT06994442)

A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer

Prostatic Neoplasms, Castration-Resistant Phase 3 Interventional 800 participants sought
Penn State Milton S. Hershey Medical Center — Hershey, Pennsylvania (12.4 mi) · Sponsor: Janssen Research & Development, LLC
See eligibility & contact on ClinicalTrials.gov (NCT07225946)

A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer Phase 2 Interventional 150 participants sought
Cancer Care Associates Of York /ID# 270971 — York, Pennsylvania (23.1 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06568939)

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma, Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7 Phase 2, Phase 3 Interventional 613 participants sought
UPMC Pinnacle Cancer Center/Community Osteopathic Campus — Harrisburg, Pennsylvania (0.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT01810913)

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Ovarian Carcinoma N/A Interventional 1,956 participants sought
Penn State Milton S Hershey Medical Center — Hershey, Pennsylvania (12.4 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04251052)

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

Metastatic Malignant Neoplasm in the Lung, Metastatic Osteosarcoma Phase 3 Interventional 62 participants sought
Penn State Children's Hospital — Hershey, Pennsylvania (12.4 mi) · Sponsor: Children's Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT05235165)

Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

Recurrent B Acute Lymphoblastic Leukemia, Recurrent B Lymphoblastic Lymphoma Phase 2 Interventional 80 participants sought
Penn State Children's Hospital — Hershey, Pennsylvania (12.4 mi) · Sponsor: Children's Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT02981628)
Google-rated

Top-rated research centers in Harrisburg

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Capital Area Research LLC

★ 5.0
875 Poplar Church Rd #330, Camp Hill, PA 17011
(717) 963-8389
"The personalized care you receive here is beyond superb! Staff is easy to talk to, knowledgeable, and always on top of things. Highly recommend!"
— Donna Preas, 5★

Penn State Health Holy Spirit Medical Center

★ 2.4
503 N 21st St, Camp Hill, PA 17011
(717) 763-2100

Hershey Center for Applied Research

★ 4.5
1214 Research Blvd, Hummelstown, PA 17036
(717) 531-8520
"I go here to be seen by my<br>Doctor to get my CPAP perception renewed.<br>The people here are very friendly and helpful.<br>I definitely recommend t…"
— Kenneth Kanode, 5★

Pennsylvania Headache Center - Camp Hill

★ 5.0
205 Grandview Ave #206, Camp Hill, PA 17011
(717) 745-6223
"The PA Headache Center and Dr Peterlin are wonderful. The medical results have been fantastic, the office is well run, and they make being a patient …"
— Kristin Behfar, 5★

Clinical Research Center-Reading

2760 Century Blvd #3, Reading, PA 19610
(610) 375-2466

Center for Vein Restoration | Dr. Tanya Flohr

★ 4.8
2025 Technology Pkwy Ste 304, Mechanicsburg, PA 17050
(443) 219-0624
"Staff is fantastic. Procedures went well. The only problem is the wait time when you get there. It was too long a wait to finally see doctor. Doc…"
— Carole Miller, 5★

Clinicaltrialmd.com

★ 5.0
2014 S Tollgate Rd Ste 207, Bel Air, MD 21015
(410) 670-3076
"Wonderful staff and easy testing. Overall, a good experience!"
— Julia, 5★

Arkview Recovery Center

★ 4.8 (142 reviews)
4950 Wilson Ln, Mechanicsburg, PA 17055
(717) 876-8222
"There's so many people that work here with good intentions but they constantly change the rules instead of talking to individual people causing probl…"
— Lucy, 1★

Penn State Health Milton S. Hershey Medical Center

★ 3.1
500 University Dr, Hershey, PA 17033
(800) 243-1455

Clinical trials in Harrisburg: what's recruiting

The Harrisburg area currently has 412 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Harrisburg, the most active research areas are:

  • Cancer & Oncology12 studies
  • Liver & Kidney2 studies
  • Heart & Vascular2 studies
  • Immune & Skin1 studies
  • Lungs & Breathing1 studies

Every listing shows the study phase, the recruiting site and its distance from Harrisburg, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Harrisburg

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Harrisburg participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Are clinical trials in Harrisburg safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Harrisburg?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Harrisburg?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Harrisburg.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Harrisburg typically complete one or two studies per year.

Paid clinical trials near Harrisburg

Other metros within reach

York, PA459 Lancaster, PA436 Reading, PA281 Frederick, MD261 Baltimore, MD1,648 Hagerstown, MD112 Washington, DC2,376 Arlington, VA2,345

More of PA

Philadelphia2,169 Pittsburgh1,236 York459 Lancaster436 Reading281 Allentown236 Scranton100 Erie91

New paid studies open every week

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