Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/NC/Winston-Salem
Updated July 2026 from ClinicalTrials.gov

Paid Clinical Trials in Winston-Salem, NC

Studies commonly pay $75 to $4,500 per completed study

602 clinical trials are currently recruiting participants within 30 miles of Winston-Salem. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

602studies recruiting
9+research centers nearby
4condition categories
Live from the NIH registry

Studies recruiting near Winston-Salem right now

Top 25 of 602 recruiting studies, sorted by proximity — each links to its official registry page

AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss

Obesity Phase 3 Interventional 600 participants sought
Medication Mgmnt, LLC_Grnsboro — Greensboro, North Carolina (26.3 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07503210)

Clinical Study of a Vaginal Cooling Device for the Treatment of Vulvovaginal Candidiasis (VVC)

Vulvovaginal Candidiasis (VVC), Yeast Vaginitis N/A Interventional 55 participants sought
Lyndhurst Clinical Research — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Coologics, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06983041)

Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD

Atherosclerotic Cardiovascular Disease (ASCVD) Phase 3 Interventional 340 participants sought
Wake Forest University Baptist Medical Center — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Novartis Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06813911)

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Recurrent Head and Neck Squamous Cell Carcinoma, Recurrent Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 188 participants sought
Cone Health Cancer Center — Greensboro, North Carolina (26.3 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04671667)

A Study to Learn About the Study Medicine Called Rimegepant in Adolescents With Frequent Migraine

Migraine Phase 3 Interventional 200 participants sought
Wake Forest University Baptist Medical Center ( WFUBMC ) — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT06616194)

A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes

Diabetes Mellitus, Type 2 Phase 2 Interventional 270 participants sought
PharmQuest — Greensboro, North Carolina (26.3 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07415954)

A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)

Relapsed Refractory Multiple Myeloma Phase 3 Interventional 508 participants sought
Research Site — Winston-Salem, North Carolina (1.0 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07391657)

Investigation of PEMF Therapy for Female Patients With IC/BPS

Interstitial Cystitis, Chronic Interstitial Cystitis N/A Interventional 75 participants sought
Wake Forest University Health Sciences — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Wake Forest University Health Sciences
See eligibility & contact on ClinicalTrials.gov (NCT05149573)

Culturally Tailored Program for Food-Insecure Adults: SPICE-D

Type 2 Diabetes Mellitus (T2D) N/A Interventional 25 participants sought
Wake Forest University Health Sciences — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Wake Forest University Health Sciences
See eligibility & contact on ClinicalTrials.gov (NCT07361341)

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Ganglioneuroblastoma, Nodular, Neuroblastoma Phase 3 Interventional 478 participants sought
Wake Forest University Health Sciences — Winston-Salem, North Carolina (1.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06172296)

Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)

Acute Myeloid Leukemia Phase 2 Interventional 93 participants sought
Wake Forest University Health Sciences — Winston-Salem, North Carolina (1.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06672146)

Fatty Acid Synthase Inhibition in Castration Refractory Prostate Cancer

Prostate Cancer, Refractory Cancer Phase 2 Interventional 50 participants sought
Wake Forest Baptist Comprehensive Cancer Center — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Wake Forest University Health Sciences
See eligibility & contact on ClinicalTrials.gov (NCT04337580)

A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine

Episodic Migraine Phase 3 Interventional 450 participants sought
Headache Wellness Center /ID# 251018 — Greensboro, North Carolina (26.3 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT05711394)

A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)

Staphylococcus Aureus Phase 1, Phase 2 Interventional 231 participants sought
Research Site — Winston-Salem, North Carolina (1.0 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06749457)

Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)

EPP, XLP Phase 3 Interventional 301 participants sought
Wake Forest University Baptist Health — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Tanabe Pharma America, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05005975)

Trauma Resuscitation With Low-Titer Group O Whole Blood or Products

Wounds and Injuries, Shock, Hemorrhagic Phase 3 Interventional 1,100 participants sought
Atrium Health Wake Forest Baptist — Winston-Salem, North Carolina (1.0 mi) · Sponsor: University of Alabama at Birmingham
See eligibility & contact on ClinicalTrials.gov (NCT05638581)

A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias

Cardiovascular, Metabolic Disease Phase 1 Interventional 90 participants sought
Research Site 13 — High Point, North Carolina (17.5 mi) · Sponsor: CRISPR Therapeutics AG
See eligibility & contact on ClinicalTrials.gov (NCT07491172)

E-PRIME For Children With Medical Complexity

Children With Medical Complexity N/A Interventional 909 participants sought
Wake Forest University Health Sciences — Winston-Salem, North Carolina (1.0 mi) · Sponsor: Wake Forest University Health Sciences
See eligibility & contact on ClinicalTrials.gov (NCT06216548)

Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

Classic Follicular Lymphoma, Follicular Lymphoma With Unusual Cytological Features Phase 3 Interventional 600 participants sought
Novant Health Forsyth Medical Center — Winston-Salem, North Carolina (1.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06337318)

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Phase 2 Interventional 2,000 participants sought
Novant Health Forsyth Medical Center — Winston-Salem, North Carolina (1.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05564390)

Intracept Minimally-invasive PROcedure for VErtebrogenic Back Pain

Chronic Low-back Pain, Vertebrogenic Pain Syndrome N/A Observational 1,500 participants sought
Novant Health Spine Specialists — Bermuda Run, North Carolina (11.3 mi) · Sponsor: Boston Scientific Corporation
See eligibility & contact on ClinicalTrials.gov (NCT06827262)
Google-rated

Top-rated research centers in Winston-Salem

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Clinical Trials of America-NC, LLC

★ 5.0
210 Charlois Blvd #110, Winston-Salem, NC 27103
"Very nice and professional atmosphere. The people there will treat you like family."
— God is real, 5★

PMG Research of Winston-Salem

★ 2.4
1901 S Hawthorne Rd #306, Winston-Salem, NC 27103
(336) 768-8062
"Took my info and said I qualified then never contacted me or returned phone calls."
— Regina Smith, 1★

Southeastern Research Center

2932 Lyndhurst Ave Ste 110, Winston-Salem, NC 27103
(336) 659-8414

Center For Clinical Research

★ 3.0 (4 reviews)
145 Kimel Park Dr #330, Winston-Salem, NC 27103
(336) 765-6181
"ABSOLUTELY NO. ABSOLUTELY NOT.<br>You can thank me later."
— K, 1★

Southeast Clinical Oncology Research Consortium

2150 Country Club Rd, Winston-Salem, NC 27104
(336) 448-1417

Maya Angelou Center for Health Equity

★ 5.0
525 Vine St #150, Winston-Salem, NC 27102
(336) 713-7600
"Congratulations to Dr. Byrd on her recent award from Reynolds to educate the next generation in STEM.<br><br>We applaud your leadership!!!"
— Sheere Mills, 5★

Wake Forest Institute for Regenerative Medicine

★ 4.9
391 Technology Way NE, Winston-Salem, NC 27101
(336) 716-2011
"Some great things going on at Wake in WINSTON-SALEM"
— Anthony Salters, 5★

The Skin Surgery Center for Clinical Research

★ 5.0
725 Highland Oaks Dr Ste 106, Winston-Salem, NC 27103
(336) 200-8208

Center of Excellence for Research, Teaching and Learning

475 Vine St, Winston-Salem, NC 27101
(336) 713-2708

Clinical trials in Winston-Salem: what's recruiting

The Winston-Salem area currently has 602 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Winston-Salem, the most active research areas are:

  • Cancer & Oncology7 studies
  • Diabetes & Metabolism5 studies
  • Heart & Vascular3 studies
  • Immune & Skin3 studies

Every listing shows the study phase, the recruiting site and its distance from Winston-Salem, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Winston-Salem

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Winston-Salem participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Winston-Salem pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Do I need to be sick to join a clinical trial in Winston-Salem?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
How do I join a study in Winston-Salem, NC?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Winston-Salem typically complete one or two studies per year.

Paid clinical trials near Winston-Salem

Other metros within reach

High Point, NC602 Greensboro, NC601 Burlington, NC761 Concord, NC630 Charlotte, NC648 Hickory, NC92 Roanoke, VA200 Gastonia, NC650

More of NC

Durham1,671 Cary1,671 Raleigh1,662 Burlington761 Gastonia650 Charlotte648 Concord630 High Point602 Greensboro601 Asheville121 Fayetteville115

New paid studies open every week

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