How much do paid clinical trials in Hickory pay?

Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.

Are clinical trials in Hickory safe?

Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.

How do I join a study in Hickory, NC?

Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.

Is compensation for clinical trials taxable?

In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.

Can I be in more than one clinical trial at a time?

Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Hickory typically complete one or two studies per year.

Paid Clinical Trials Hickory, NC — 92 Studies Recruiting (Jul 2026)

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

Neovascular Age-related Macular Degeneration Phase 4 Interventional 188 participants sought

Graystone Eye — Hickory, North Carolina (1.2 mi) · Sponsor: Genentech, Inc.

See eligibility & contact on ClinicalTrials.gov (NCT04853251)

A Study to Evaluate the Efficacy and Safety of E2086 in Adults With Narcolepsy

Narcolepsy Phase 2 Interventional 64 participants sought

Research Carolina Elite — Denver, North Carolina (21.9 mi) · Sponsor: Eisai Inc.

See eligibility & contact on ClinicalTrials.gov (NCT07493265)

A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes

Diabetes Mellitus, Type 2 Phase 2 Interventional 270 participants sought

Piedmont Healthcare Statesville — Statesville, North Carolina (24.6 mi) · Sponsor: Novo Nordisk A/S

See eligibility & contact on ClinicalTrials.gov (NCT07415954)

Study to Determine if BHV-1300 is Effective and Safe in Adults With Graves' Disease

Graves Disease Phase 3 Interventional 300 participants sought

Site-033 — Statesville, North Carolina (24.6 mi) · Sponsor: Biohaven Therapeutics Ltd.

See eligibility & contact on ClinicalTrials.gov (NCT07661056)

A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

Narcolepsy Type 1, Narcolepsy Type 2 Phase 2 Interventional 90 participants sought

Denver, North Carolina — Denver, North Carolina (21.9 mi) · Sponsor: Centessa Pharmaceuticals (UK) Limited

See eligibility & contact on ClinicalTrials.gov (NCT07096674)

Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)

Neovascular Age-Related Macular Degeneration (nAMD), Wet AMD Phase 3 Interventional 284 participants sought

Adverum Clinical Site 220 — Hickory, North Carolina (1.2 mi) · Sponsor: Adverum Biotechnologies, Inc.

See eligibility & contact on ClinicalTrials.gov (NCT07482176)

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

Breast Carcinoma, Colorectal Carcinoma N/A Observational 2,000 participants sought

CaroMont Health - Lincoln Cancer Center — Lincolnton, North Carolina (18.9 mi) · Sponsor: Wake Forest University Health Sciences

See eligibility & contact on ClinicalTrials.gov (NCT06418204)

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

Prostate Cancer (Adenocarcinoma) Phase 3 Interventional 830 participants sought

Atrium Health Lincoln/LCI-Lincolnton — Lincolnton, North Carolina (18.9 mi) · Sponsor: Canadian Cancer Trials Group

See eligibility & contact on ClinicalTrials.gov (NCT06592924)

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

Stage I Breast Cancer Phase 3 Interventional 1,670 participants sought

Novant Health Cancer Institute - Statesville — Statesville, North Carolina (24.6 mi) · Sponsor: NRG Oncology

See eligibility & contact on ClinicalTrials.gov (NCT04852887)

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

NASH With Fibrosis, MASH With Fibrosis Phase 3 Interventional 1,650 participants sought

Akero Clinical Study Site — Statesville, North Carolina (24.6 mi) · Sponsor: Akero Therapeutics, Inc

See eligibility & contact on ClinicalTrials.gov (NCT06215716)

Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

Extensive Stage Lung Small Cell Carcinoma Phase 2, Phase 3 Interventional 138 participants sought

Atrium Health Lincoln/LCI-Lincolnton — Lincolnton, North Carolina (18.9 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT04402788)

An Extension Study to Assess Long-Term Safety and Tolerability of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia

Schizophrenia Phase 3 Interventional 280 participants sought

Local Institution - 176 — Hickory, North Carolina (1.2 mi) · Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

See eligibility & contact on ClinicalTrials.gov (NCT05304767)

A Study to Learn About the Study Medicine Called Zavegepant (PF-07930207) in Children With a History of Migraine

Acute Treatment of Migraine Phase 1 Interventional 16 participants sought

Accellacare - Piedmont — Statesville, North Carolina (24.6 mi) · Sponsor: Pfizer

See eligibility & contact on ClinicalTrials.gov (NCT06995729)

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Lung Non-Small Cell Carcinoma, Lung Non-Small Cell Squamous Carcinoma Phase 3 Interventional 1,210 participants sought

Wake Forest Baptist Health - Hematology Oncology - Statesville — Statesville, North Carolina (24.6 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT04267848)

Shield Post-Approval Study Protocol

Colo-rectal Cancer N/A Observational 3,375 participants sought

Piedmont Healthcare LLC — Statesville, North Carolina (24.6 mi) · Sponsor: Guardant Health, Inc.

See eligibility & contact on ClinicalTrials.gov (NCT06880055)

ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 Phase 3 Interventional 1,524 participants sought

Novant Health Cancer Institute - Statesville — Statesville, North Carolina (24.6 mi) · Sponsor: Alliance for Clinical Trials in Oncology

See eligibility & contact on ClinicalTrials.gov (NCT06876714)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought

Novant Health Cancer Institute - Statesville — Statesville, North Carolina (24.6 mi) · Sponsor: SWOG Cancer Research Network

See eligibility & contact on ClinicalTrials.gov (NCT03851445)

A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

Graves' Disease Phase 2 Interventional 210 participants sought

Site Number - 1026 — Hickory, North Carolina (1.2 mi) · Sponsor: Immunovant Sciences GmbH

See eligibility & contact on ClinicalTrials.gov (NCT07018323)

A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults

Chronic Idiopathic Constipation (CIC) Phase 3 Interventional 692 participants sought

Accellacare of Piedmont HealthCare — Statesville, North Carolina (24.6 mi) · Sponsor: Ardelyx

See eligibility & contact on ClinicalTrials.gov (NCT07382167)

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

Metastatic Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8 Phase 2 Interventional 240 participants sought

Wake Forest Baptist Health - Wilkes Medical Center — Wilkesboro, North Carolina (29.4 mi) · Sponsor: NRG Oncology

See eligibility & contact on ClinicalTrials.gov (NCT05327686)

Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)

Migraine Phase 3 Interventional 1,059 participants sought

OnSite Clinical Solutions - Ninth Ave Drive North East - Hickory /ID# 227994 — Hickory, North Carolina (1.2 mi) · Sponsor: AbbVie

See eligibility & contact on ClinicalTrials.gov (NCT05125302)

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

Muscle Invasive Bladder Urothelial Carcinoma, Muscle Invasive Renal Pelvis Urothelial Carcinoma Phase 2, Phase 3 Interventional 992 participants sought

Atrium Health Lincoln/LCI-Lincolnton — Lincolnton, North Carolina (18.9 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT05987241)

AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

Obesity, Overweight Phase 3 Interventional 400 participants sought

Piedmont Healthcare/Research — Statesville, North Carolina (24.6 mi) · Sponsor: Novo Nordisk A/S

See eligibility & contact on ClinicalTrials.gov (NCT07509307)

Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

Depressive Disorder, Major Phase 3 Interventional 752 participants sought

IMA Clinical Research PC 3 — Hickory, North Carolina (1.2 mi) · Sponsor: Janssen Research & Development, LLC

See eligibility & contact on ClinicalTrials.gov (NCT06559306)

An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)

Progressive Pulmonary Fibrosis, Idiopathic Pulmonary Fibrosis (IPF) Phase 2 Interventional 340 participants sought

Piedmont HealthCare, PA — Statesville, North Carolina (24.6 mi) · Sponsor: Avalyn Pharma Inc.

See eligibility & contact on ClinicalTrials.gov (NCT06951217)

Paid Clinical Trials in Hickory, NC

Studies recruiting near Hickory right now

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

A Study to Evaluate the Efficacy and Safety of E2086 in Adults With Narcolepsy

A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes

Study to Determine if BHV-1300 is Effective and Safe in Adults With Graves' Disease

A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

An Extension Study to Assess Long-Term Safety and Tolerability of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia

A Study to Learn About the Study Medicine Called Zavegepant (PF-07930207) in Children With a History of Migraine

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Shield Post-Approval Study Protocol

ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)

Top-rated research centers in Hickory

PMG Research of Hickory

IMA Clinical Research

Clinical Trials of America

Piedmont Endocrinology

Clinical Research of Gastonia

Rose Research Center

DelRicht Research | Charlotte Clinical Trials

Queen City Clinical Research, PLLC

New Hope Clinical Research, Inc.

Clinical trials in Hickory: what's recruiting

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