Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/NC/Wilmington
Updated July 2026 from ClinicalTrials.gov

Paid Clinical Trials in Wilmington, NC

Studies commonly pay $75 to $4,500 per completed study

107 clinical trials are currently recruiting participants within 30 miles of Wilmington. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

107studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Wilmington right now

Top 25 of 107 recruiting studies, sorted by proximity — each links to its official registry page

AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss

Obesity Phase 3 Interventional 600 participants sought
PMG Research of Wilmington LLC — Wilmington, North Carolina (3.8 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07503210)

A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

Obesity, Knee Osteoarthritis (OA) Phase 3 Interventional 400 participants sought
Accellacare and KDCILM, LLC — Wilmington, North Carolina (3.8 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07481630)

A Study to Assess the Safety and Efficacy of Different Doses of ELV001 to Treat Active Rheumatoid Arthritis in Patients With an Inadequate Response to Methotrexate and Tumor Necrosis Factor Inhibition (START SYNERGY)

Active Rheumatoid Arthritis Phase 2 Interventional 180 participants sought
Carolina Arthritis Associates - Cliniverse Research (Network) — Wilmington, North Carolina (3.8 mi) · Sponsor: Elevara Medicines Limited
See eligibility & contact on ClinicalTrials.gov (NCT07409103)

Evaluation of Efficacy and Safety of THRV-1268 in Long QT Syndrome Type 2 (LQTS 2)

Long QT Syndrome (LQTS) 2 Phase 2, Phase 3 Interventional 64 participants sought
Wilmington Health — Wilmington, North Carolina (3.8 mi) · Sponsor: Thryv Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07277582)

A Study to Describe the Real-world Effectiveness, Safety and Patterns of Use of Dupilumab in Patients With Chronic Spontaneous Urticaria

Chronic Spontaneous Urticaria N/A Observational 400 participants sought
Virtual Research Coordination Center — Wilmington, North Carolina (3.8 mi) · Sponsor: Sanofi
See eligibility & contact on ClinicalTrials.gov (NCT07316114)

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Phase 2 Interventional 2,000 participants sought
Novant Health New Hanover Regional Medical Center — Wilmington, North Carolina (3.8 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05564390)

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)

Chronic Obstructive Pulmonary Disease (COPD) Phase 3 Interventional 990 participants sought
Research Site — Wilmington, North Carolina (3.8 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06883305)

Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events

Obesity, Overweight Phase 1 Interventional 114 participants sought
Accellacare — Wilmington, North Carolina (3.8 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07607587)

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Ovarian Carcinoma N/A Interventional 1,956 participants sought
Novant Health New Hanover Regional Medical Center — Wilmington, North Carolina (3.8 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04251052)

A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease

Degenerative Disc Disease Phase 3 Interventional 162 participants sought
Wake Research — Wilmington, North Carolina (3.8 mi) · Sponsor: DiscGenics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07254806)

Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne

Acne Phase 1, Phase 2 Interventional 800 participants sought
Trial Management Associates - Wilmington - Floral Parkway- Site Number : 8400104 — Wilmington, North Carolina (3.8 mi) · Sponsor: Sanofi Pasteur, a Sanofi Company
See eligibility & contact on ClinicalTrials.gov (NCT06316297)

ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 Phase 3 Interventional 1,524 participants sought
Novant Health New Hanover Regional Medical Center — Wilmington, North Carolina (3.8 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06876714)

Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry

Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease N/A Observational 3,000 participants sought
PMG Research — Wilmington, North Carolina (3.8 mi) · Sponsor: Duke University
See eligibility & contact on ClinicalTrials.gov (NCT01915511)

Tenosynovial Giant Cell Tumor (TGCT) Real-World Participant Experience With Vimseltinib

Tenosynovial Giant Cell Tumor N/A Observational 100 participants sought
Synexus Clinical Research, US INC — Wilmington, North Carolina (3.8 mi) · Sponsor: Deciphera Pharmaceuticals, LLC
See eligibility & contact on ClinicalTrials.gov (NCT07075471)

A Study to Assess the Safety and Effectiveness of ELAPR002f Injectable Gel in Adult Participants With Atrophic Acne Scars

Acne Scars Phase 3 Interventional 395 participants sought
Wilmington Dermatology Center /ID# 256192 — Wilmington, North Carolina (3.8 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT07207369)

A Study to Train a Machine Learning Algorithm for an Evaluation of the Use of Biometric Data Captured at the Wrist for the Identification of Acute Opioid Use Events and the Quantification of Opioid Withdrawal in Opioid Dependent Individuals

Treatment for Opioid Use Disorder N/A Interventional 420 participants sought
Coastal Horizon — Wilmington, North Carolina (3.8 mi) · Sponsor: OpiAID
See eligibility & contact on ClinicalTrials.gov (NCT07405398)

Antiretroviral Pregnancy Registry (APR): Multi-sponsor Registry to Detect Any Major Teratogenic Effect Involving Any of the Registry Drugs When Administered to Pregnant People.

HIV Infections, Hepatitis B N/A Observational 24,258 participants sought
Registry Coordinating Center — Wilmington, North Carolina (3.8 mi) · Sponsor: Syneos Health
See eligibility & contact on ClinicalTrials.gov (NCT00404989)

AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight

Obesity Phase 3 Interventional 1,150 participants sought
Accellacare and KDCILM, LLC — Wilmington, North Carolina (3.8 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07339423)

A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

Chronic Kidney Disease and Hypertension Phase 3 Interventional 5,000 participants sought
Research Site — Wilmington, North Carolina (3.8 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06742723)

A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes

Diabetes Mellitus, Type 2 Phase 2 Interventional 300 participants sought
KDCILM, LLC & Accellacare US, Inc. — Wilmington, North Carolina (3.8 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07668388)
Google-rated

Top-rated research centers in Wilmington

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Accellacare Research of Wilmington

★ 4.9
1907 Tradd Ct, Wilmington, NC 28401
(910) 799-5500
"My experience with PMG Research of Wilmington has been just great.<br>the staff there are always very friendly and very professional. they always mak…"
— Cynthia Williamson, 5★

PMG Research of Wilmington

★ 4.0
1202 Medical Center Dr, Wilmington, NC 28401
(910) 815-6108

M3 Wake Research Wilmington

2716 Ashton Dr, Wilmington, NC 28412
(910) 408-5746

Catalyst Clinical Research

2528 Independence Blvd Ste 100, Wilmington, NC 28412
(919) 648-0668

WDC Clinical Research Center

710 Military Cutoff Rd Ste 220, Wilmington, NC 28405
(910) 726-9346

PharPoint Research, Inc.

★ 5.0
21 S Front St Ste 200, Wilmington, NC 28401
(910) 790-0482
"Very good! I'm happy to see such wonderful Souls diving deep into helping Humanity."
— MindOps, 5★

Novant Health New Hanover Regional Medical Center

★ 3.1
2131 S 17th St, Wilmington, NC 28401
(910) 667-7000
"Nurses took great care of me and honored all my requests. And the surgery must have gone well, because I came out great!"
— david kirk, 5★

Coastal Horizons Center

★ 2.8 (89 reviews)
615 Shipyard Blvd, Wilmington, NC 28412
(910) 343-0145
"Switched here from Better Life Partners, which was an awesome program. This place sucks. I've been in the lobby for 3 1/2 hours waiting to be called,…"
— Joshua Ward, 1★

Eastcoast Research

★ 5.0
1213 Culbreth Dr Ste 208, Wilmington, NC 28405
(910) 763-3260
"Did a one on one discussion with a narrator. She was very professional and polite. It was very easy and a good experience."
— Barbara Baize, 5★

Clinical trials in Wilmington: what's recruiting

The Wilmington area currently has 107 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Wilmington, the most active research areas are:

  • Diabetes & Metabolism7 studies
  • Cancer & Oncology4 studies
  • Immune & Skin3 studies
  • Lungs & Breathing2 studies
  • Liver & Kidney2 studies

Every listing shows the study phase, the recruiting site and its distance from Wilmington, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Wilmington

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Wilmington participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Wilmington pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Wilmington safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Wilmington, NC?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
How often do new paid studies open in Wilmington?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Wilmington.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Wilmington typically complete one or two studies per year.

Paid clinical trials near Wilmington

Other metros within reach

Myrtle Beach, SC86 Fayetteville, NC115 Raleigh, NC1,662 Cary, NC1,671 Durham, NC1,671 Burlington, NC761 Charleston, SC734 Greensboro, NC601

More of NC

Durham1,671 Cary1,671 Raleigh1,662 Burlington761 Gastonia650 Charlotte648 Concord630 High Point602 Winston-Salem602 Greensboro601 Asheville121 Fayetteville115

New paid studies open every week

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