Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/NC/Wilmington
Updated September 2026 from ClinicalTrials.gov

Paid Clinical Trials in Wilmington, NC

Studies commonly pay $75 to $4,500 per completed study

115 clinical trials are currently recruiting participants within 30 miles of Wilmington. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

115studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Wilmington right now

Top 25 of 115 recruiting studies, sorted by proximity — each links to its official registry page

Odevixibat Pregnancy and Lactation Surveillance Program: A Study to Evaluate the Safety of Odevixibat During Pregnancy and/or Lactation

Pregnancy Related N/A Observational 20 participants sought
Virtual Research Coordination Center Odevixibat (BYLVAY) Pregnancy Surveillance Program — Wilmington, North Carolina (3.8 mi) · Sponsor: Ipsen
See eligibility & contact on ClinicalTrials.gov (NCT06258902)

A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight

Overweight, Obesity Phase 3 Interventional 285 participants sought
KDCILM, LLC & Accellacare US, Inc. — Wilmington, North Carolina (3.8 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07745504)

Safety and Effectiveness Evaluation of the High-intensity Focused Ultrasound Device for Lifting Lax Submental and Neck Tissue

Skin Laxity (Submental and Neck), Facial Skin Laxity N/A Interventional 273 participants sought
Dermatology — Wilmington, North Carolina (3.8 mi) · Sponsor: CLASSYS Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07229430)

Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

Heart Failure, Cardiorenal Syndrome N/A Interventional 320 participants sought
Novant Health New Hanover Regional Medical Center — Wilmington, North Carolina (3.8 mi) · Sponsor: Procyrion
See eligibility & contact on ClinicalTrials.gov (NCT05677100)

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

Melanoma Phase 3 Interventional 560 participants sought
Novant Health Zimmer Cancer Institute - Wilmington — Wilmington, North Carolina (3.8 mi) · Sponsor: Regeneron Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06246916)

AtraUmatic Laparoscopic HerNia Repair Clinical Investigation to Evaluate the Safety and Performance of The ECLIPSIUM System for Mesh Fixation IDE

Hernia N/A Interventional 240 participants sought
Novant Health New Hanover Regional Medical Center — Wilmington, North Carolina (3.8 mi) · Sponsor: Tissium
See eligibility & contact on ClinicalTrials.gov (NCT07277946)

Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response

Arthritis, Psoriatic Phase 3 Interventional 600 participants sought
Clinical Site — Leland, North Carolina (9.6 mi) · Sponsor: MoonLake Immunotherapeutics AG
See eligibility & contact on ClinicalTrials.gov (NCT06641089)

A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia

Hypercholesterolemia Phase 2 Interventional 420 participants sought
Accellacare of Wilmington — Wilmington, North Carolina (3.8 mi) · Sponsor: Regeneron Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT07477704)

MOVE: Tenosynovial Giant Cell Tumor (TGCT) Real-World Participant Experience With Vimseltinib

Tenosynovial Giant Cell Tumor N/A Observational 100 participants sought
Synexus Clinical Research, US INC — Wilmington, North Carolina (3.8 mi) · Sponsor: Deciphera Pharmaceuticals, LLC
See eligibility & contact on ClinicalTrials.gov (NCT07075471)

A Study to Assess the Safety and Efficacy of Different Doses of ELV001 to Treat Active Rheumatoid Arthritis in Patients With an Inadequate Response to Methotrexate and Tumor Necrosis Factor Inhibition (START SYNERGY)

Active Rheumatoid Arthritis Phase 2 Interventional 180 participants sought
Carolina Arthritis Associates - Cliniverse Research (Network) — Wilmington, North Carolina (3.8 mi) · Sponsor: Elevara Medicines Limited
See eligibility & contact on ClinicalTrials.gov (NCT07409103)

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis Phase 3 Interventional 1,350 participants sought
89bio Clinical Study Site — Wilmington, North Carolina (3.8 mi) · Sponsor: 89bio, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06318169)

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

Locally Advanced Cervical Adenocarcinoma, Locally Advanced Cervical Adenosquamous Carcinoma Phase 3 Interventional 336 participants sought
Novant Health Cancer Institute Radiation Oncology - Wilmington — Wilmington, North Carolina (3.8 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT07061977)

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

Miscellaneous Neoplasm, Nos, Non-Neoplastic Condition, Nos N/A Interventional 535 participants sought
Novant Health New Hanover Regional Medical Center — Wilmington, North Carolina (3.8 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT07091617)

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

Endometrial Carcinoma, Endometrial Clear Cell Adenocarcinoma Phase 3 Interventional 360 participants sought
Novant Health New Hanover Regional Medical Center — Wilmington, North Carolina (3.8 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05256225)

Open Label Study to Investigate the Safety and Efficacy of Ponesimod in Moderate-to-Severe Chronic Plaque Psoriasis

Moderate-to-severe Chronic Plaque Psoriasis Phase 3 Interventional 300 participants sought
Vanda Investigational Site — Wilmington, North Carolina (3.8 mi) · Sponsor: Vanda Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT07362017)

Dose Ranging Study of ORKA-002 in Patients With Moderate-to-Severe Plaque Psoriasis

Plaque Psoriasis Phase 2 Interventional 160 participants sought
Oruka Therapeutics Investigative Site — Wilmington, North Carolina (3.8 mi) · Sponsor: Oruka Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07474792)

A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's Disease

Crohn Disease Phase 2 Interventional 60 participants sought
Innovo Research - Wilmington Gastroenterology Associates — Wilmington, North Carolina (3.8 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07483099)

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Phase 2 Interventional 2,000 participants sought
Novant Health New Hanover Regional Medical Center — Wilmington, North Carolina (3.8 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05564390)

A Study to Assess Safety and Tolerability of PCRX-201 in Subjects With Painful Osteoarthritis of the Knee

Osteoarthritis (OA) of the Knee Phase 2 Interventional 135 participants sought
M3 Wake Research - Wilmington, NC — Wilmington, North Carolina (3.8 mi) · Sponsor: Pacira Pharmaceuticals, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06884865)

Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma

Multiple Myeloma, Cancer Phase 2 Interventional 50 participants sought
Novant Health New Hanover Regional Medical Center — Wilmington, North Carolina (3.8 mi) · Sponsor: UNC Lineberger Comprehensive Cancer Center
See eligibility & contact on ClinicalTrials.gov (NCT05145400)
Actively enrolling

Studies you may be able to join near Wilmington

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Wilmington

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Accellacare Research of Wilmington

★ 4.9
1907 Tradd Ct, Wilmington, NC 28401
(910) 799-5500
"My experience with PMG Research of Wilmington has been just great.<br>the staff there are always very friendly and very professional. they always mak…"
— Cynthia Williamson, 5★

PMG Research of Wilmington

★ 4.0
1202 Medical Center Dr, Wilmington, NC 28401
(910) 815-6108

M3 Wake Research Wilmington

2716 Ashton Dr, Wilmington, NC 28412
(910) 408-5746

Catalyst Clinical Research

2528 Independence Blvd Ste 100, Wilmington, NC 28412
(919) 648-0668

WDC Clinical Research Center

710 Military Cutoff Rd Ste 220, Wilmington, NC 28405
(910) 726-9346

PharPoint Research, Inc.

★ 5.0
21 S Front St Ste 200, Wilmington, NC 28401
(910) 790-0482
"Very good! I'm happy to see such wonderful Souls diving deep into helping Humanity."
— MindOps, 5★

Novant Health New Hanover Regional Medical Center

★ 3.1
2131 S 17th St, Wilmington, NC 28401
(910) 667-7000
"Nurses took great care of me and honored all my requests. And the surgery must have gone well, because I came out great!"
— david kirk, 5★

Coastal Horizons Center

★ 2.8 (89 reviews)
615 Shipyard Blvd, Wilmington, NC 28412
(910) 343-0145
"Switched here from Better Life Partners, which was an awesome program. This place sucks. I've been in the lobby for 3 1/2 hours waiting to be called,…"
— Joshua Ward, 1★

Eastcoast Research

★ 5.0
1213 Culbreth Dr Ste 208, Wilmington, NC 28405
(910) 763-3260
"Did a one on one discussion with a narrator. She was very professional and polite. It was very easy and a good experience."
— Barbara Baize, 5★

Clinical trials in Wilmington: what's recruiting

The Wilmington area currently has 115 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Wilmington, the most active research areas are:

  • Immune & Skin7 studies
  • Cancer & Oncology6 studies
  • Diabetes & Metabolism3 studies
  • Liver & Kidney2 studies
  • Heart & Vascular1 studies

Every listing shows the study phase, the recruiting site and its distance from Wilmington, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Wilmington

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Wilmington participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Wilmington pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Wilmington safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Wilmington, NC?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
How often do new paid studies open in Wilmington?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Wilmington.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Wilmington typically complete one or two studies per year.

Paid clinical trials near Wilmington

Other metros within reach

Myrtle Beach, SC89 Fayetteville, NC123 Raleigh, NC1,684 Cary, NC1,692 Durham, NC1,692 Burlington, NC758 Charleston, SC732 Greensboro, NC589

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Wilmington Chronic Kidney Disease (HealthMatch) in Wilmington Bladder Issues Due To Spinal Cord Injury in Wilmington All conditions

More of NC

Durham1,692 Cary1,692 Raleigh1,684 Burlington758 Charlotte660 Gastonia655 Concord639 High Point590 Winston-Salem590 Greensboro589 Fayetteville123 Asheville121

New paid studies open every week

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