Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/KY/Louisville
Updated July 2026 from ClinicalTrials.gov

Paid Clinical Trials in Louisville, KY

Studies commonly pay $75 to $4,500 per completed study

576 clinical trials are currently recruiting participants within 30 miles of Louisville. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

576studies recruiting
1+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Louisville right now

Top 25 of 576 recruiting studies, sorted by proximity — each links to its official registry page

Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research Design

Fibromyalgia Phase 3 Interventional 620 participants sought
Clinical Research Site — Louisville, Kentucky (8.6 mi) · Sponsor: Axsome Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07398417)

Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair

Hand Transplantation, Peripheral Nerve Injuries N/A Interventional 180 participants sought
Christine Kleinert Institute for Hand & Microsurgery — Louisville, Kentucky (8.6 mi) · Sponsor: University of Missouri-Columbia
See eligibility & contact on ClinicalTrials.gov (NCT03610763)

A Clinical Study of Raludotatug Deruxtecan in People With Ovarian Cancer (MK-5909-003)

Ovarian Cancer Recurrent Phase 1, Phase 2 Interventional 460 participants sought
The University of Louisville, James Graham Brown Cancer Center ( Site 0009) — Louisville, Kentucky (8.6 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06843447)

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Recurrent Head and Neck Squamous Cell Carcinoma, Recurrent Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 188 participants sought
The James Graham Brown Cancer Center at University of Louisville — Louisville, Kentucky (8.6 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04671667)

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

Brain Cancer, Breast Cancer N/A Observational 7,000 participants sought
Baptist Floyd — New Albany, Indiana (12.6 mi) · Sponsor: Adela, Inc
See eligibility & contact on ClinicalTrials.gov (NCT05366881)

A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)

Relapsed Refractory Multiple Myeloma Phase 3 Interventional 508 participants sought
Research Site — Louisville, Kentucky (8.6 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07391657)

The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)

Coronary Artery Disease, Heart Failure Systolic N/A Interventional 754 participants sought
UofL Health, Inc — Louisville, Kentucky (8.6 mi) · Sponsor: Sunnybrook Health Sciences Centre
See eligibility & contact on ClinicalTrials.gov (NCT05427370)

Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis

Ulcerative Colitis (UC) Phase 1, Phase 2 Interventional 270 participants sought
Xencor Investigative Site — Louisville, Kentucky (8.6 mi) · Sponsor: Xencor, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06619990)

Dome-Only Aneurysm Coiling in Severe Aneurysmal Subarachnoid Hemorrhage

Aneurysmal Subarachnoid Hemorrhage N/A Observational 30 participants sought
University of Louisville Hospital — Louisville, Kentucky (8.6 mi) · Sponsor: University of Louisville
See eligibility & contact on ClinicalTrials.gov (NCT07250958)

A Post-Authorisation Safety Study (PASS) of Patients Treated With Lonapegsomatropin

Growth Hormone Deficiency N/A Observational 500 participants sought
Ascendis Investigational Site — Louisville, Kentucky (8.6 mi) · Sponsor: Ascendis Pharma Endocrinology Division A/S
See eligibility & contact on ClinicalTrials.gov (NCT05775523)

Health, Environment and Action in Louisville (HEAL) Green Heart Louisville Project

Cardiovascular Diseases, Metabolic Health N/A Interventional 835 participants sought
University of Louisville — Louisville, Kentucky (8.6 mi) · Sponsor: University of Louisville
See eligibility & contact on ClinicalTrials.gov (NCT03670524)

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Ganglioneuroblastoma, Nodular, Neuroblastoma Phase 3 Interventional 478 participants sought
Norton Children's Hospital — Louisville, Kentucky (8.6 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06172296)

Saline Versus Balanced Crystalloid in Traumatic Brain Injury

Traumatic Brain Injury (TBI) Patients Phase 3 Interventional 600 participants sought
University of Louisville Hospital — Louisville, Kentucky (8.6 mi) · Sponsor: University of Louisville
See eligibility & contact on ClinicalTrials.gov (NCT06953674)

Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)

Acute Myeloid Leukemia Phase 2 Interventional 93 participants sought
The James Graham Brown Cancer Center at University of Louisville — Louisville, Kentucky (8.6 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06672146)

Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

Ovarian Cancer, Fallopian Tube Cancer Phase 2 Interventional 220 participants sought
Norton Cancer Institute, St. Matthews Clinic — Louisville, Kentucky (8.6 mi) · Sponsor: Regeneron Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06787612)

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

Plasma Cell Myeloma, RISS Stage I Plasma Cell Myeloma Phase 3 Interventional 1,450 participants sought
Jewish Hospital — Louisville, Kentucky (8.6 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT04566328)

ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer

Breast Neoplasms Phase 3 Interventional 558 participants sought
University Medical Center, Inc. DBA University of Louisville Hospital/James Graham Brown Cancer Center — Louisville, Kentucky (8.6 mi) · Sponsor: BioNTech SE
See eligibility & contact on ClinicalTrials.gov (NCT07173751)

Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

Metastatic Clear Cell Renal Cell Carcinoma, Advanced Clear Cell Renal Cell Carcinoma Phase 3 Interventional 720 participants sought
Research Site — Louisville, Kentucky (8.6 mi) · Sponsor: Arcus Biosciences, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07011719)

Safety and Tolerability Study of GIM-122 in Subjects With Advanced Solid Malignancies

Advanced Solid Malignancies Phase 1, Phase 2 Interventional 111 participants sought
Norton Cancer Institute — Louisville, Kentucky (8.6 mi) · Sponsor: Georgiamune Inc
See eligibility & contact on ClinicalTrials.gov (NCT06028074)

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Phase 2 Interventional 2,000 participants sought
The James Graham Brown Cancer Center at University of Louisville — Louisville, Kentucky (8.6 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05564390)
Google-rated

Top-rated research centers in Louisville

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

L-MARC Research Center

★ 4.8
3288 Illinois Ave Unit 101, Louisville, KY 40213
(502) 515-5672
"The most wonderful knowledge staff on the planet and I look forward to my visits. Every visit is smooth and consistent."
— D. L., 5★

Clinical trials in Louisville: what's recruiting

The Louisville area currently has 576 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Louisville, the most active research areas are:

  • Cancer & Oncology11 studies
  • Heart & Vascular3 studies
  • Immune & Skin2 studies
  • Liver & Kidney2 studies
  • Diabetes & Metabolism1 studies

Every listing shows the study phase, the recruiting site and its distance from Louisville, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Louisville

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Louisville participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Louisville pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Louisville safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in Louisville?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Louisville.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Louisville typically complete one or two studies per year.

Paid clinical trials near Louisville

Other metros within reach

Lexington, KY467 Cincinnati, OH1,137 Indianapolis, IN915 Evansville, IN67 Dayton, OH309 Nashville, TN1,336 Clarksville, TN9 Murfreesboro, TN79

More of KY

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New paid studies open every week

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