Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/IN/Indianapolis
Updated July 2026 from ClinicalTrials.gov

Paid Clinical Trials in Indianapolis, IN

Studies commonly pay $75 to $4,500 per completed study

915 clinical trials are currently recruiting participants within 30 miles of Indianapolis. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

915studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Indianapolis right now

Top 25 of 915 recruiting studies, sorted by proximity — each links to its official registry page

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
Community Health Network, Inc — Indianapolis, Indiana (0.9 mi) · Sponsor: Relay Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06982521)

AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss

Obesity Phase 3 Interventional 600 participants sought
Midwest Inst For Clin Res — Indianapolis, Indiana (0.9 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07503210)

Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures: A Pragmatic, Randomized Controlled Trial

Tibial Fractures, Pain Phase 3 Interventional 1,000 participants sought
Eskenazi Hospital — Indianapolis, Indiana (0.9 mi) · Sponsor: Major Extremity Trauma Research Consortium
See eligibility & contact on ClinicalTrials.gov (NCT07006675)

A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

Ulcerative Colitis, Crohn's Disease Phase 3 Interventional 240 participants sought
Riley Hospital For Children - PIN — Indianapolis, Indiana (0.9 mi) · Sponsor: Takeda
See eligibility & contact on ClinicalTrials.gov (NCT05442567)

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

Carcinoma, Non-Small Cell Lung, Squamous Cell Carcinoma of Head and Neck Phase 1 Interventional 1,006 participants sought
Community Health Network, Inc — Indianapolis, Indiana (0.9 mi) · Sponsor: Seagen, a wholly owned subsidiary of Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT04389632)

Type 1 Diabetes Extension Study

Type 1 Diabetes Mellitus, T1DM N/A Observational 111 participants sought
Indiana University Riley Hospital for Children — Indianapolis, Indiana (0.9 mi) · Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
See eligibility & contact on ClinicalTrials.gov (NCT02734277)

Pre-Rehabilitation for Female Patients Undergoing Pelvic Radiotherapy

Dyspareunia, Pelvic Pain N/A Interventional 20 participants sought
Indiana University Melvin and Bren Simon Comprehensive Cancer Center — Indianapolis, Indiana (0.9 mi) · Sponsor: Indiana University
See eligibility & contact on ClinicalTrials.gov (NCT06059586)

A Study to Assess Real-World Use and Outcomes of TAR-200 for Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) in the United States

Non-Muscle Invasive Bladder Neoplasms N/A Observational 150 participants sought
Indiana University Melvin and Bren Simon Cancer Center — Indianapolis, Indiana (0.9 mi) · Sponsor: Janssen Research & Development, LLC
See eligibility & contact on ClinicalTrials.gov (NCT07309445)

Comparison of Uncomplicated Candidemia Therapy Duration in Children

Invasive Candidiasis N/A Interventional 420 participants sought
Riley Children's Hospital — Indianapolis, Indiana (0.9 mi) · Sponsor: Arkansas Children's Hospital Research Institute
See eligibility & contact on ClinicalTrials.gov (NCT05763251)

Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL)

Acute Stress Reaction, Acute Stress Disorder Phase 2 Interventional 180 participants sought
Indiana University — Indianapolis, Indiana (0.9 mi) · Sponsor: University of North Carolina, Chapel Hill
See eligibility & contact on ClinicalTrials.gov (NCT06636786)

A Study to Investigate Safety and Efficacy of Tapinarof Cream, 1% in Participants Ages 3 Months to < 24 Months With Atopic Dermatitis

Atopic Dermatitis Phase 3 Interventional 180 participants sought
Dawes Fretzin Clinical Research Group, LLC — Indianapolis, Indiana (0.9 mi) · Sponsor: Organon and Co
See eligibility & contact on ClinicalTrials.gov (NCT07265479)

A Post-Authorisation Safety Study (PASS) of Patients Treated With Lonapegsomatropin

Growth Hormone Deficiency N/A Observational 500 participants sought
Ascendis Investigational Site — Indianapolis, Indiana (0.9 mi) · Sponsor: Ascendis Pharma Endocrinology Division A/S
See eligibility & contact on ClinicalTrials.gov (NCT05775523)

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Ganglioneuroblastoma, Nodular, Neuroblastoma Phase 3 Interventional 478 participants sought
Riley Hospital for Children — Indianapolis, Indiana (0.9 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06172296)

Evaluation of a Mixed Meal Test for Diagnosis and Characterization and Type 3c Diabetes Mellitus Secondary to Pancreatic Cancer and Chronic Pancreatitis (DETECT)

Pancreatic Cancer, Chronic Pancreatitis N/A Observational 775 participants sought
Indiana University — Carmel, Indiana (14.0 mi) · Sponsor: M.D. Anderson Cancer Center
See eligibility & contact on ClinicalTrials.gov (NCT03460769)

A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo

NonSegmental Vitiligo Phase 3 Interventional 180 participants sought
Indiana University School of Medicine — Indianapolis, Indiana (0.9 mi) · Sponsor: Incyte Corporation
See eligibility & contact on ClinicalTrials.gov (NCT06548360)

A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)

Sickle Cell Disease Phase 1 Interventional 24 participants sought
Innovative Hematology - Indiana Hemophilia & Thrombosis Center — Indianapolis, Indiana (0.9 mi) · Sponsor: Disc Medicine, Inc
See eligibility & contact on ClinicalTrials.gov (NCT07187973)
Google-rated

Top-rated research centers in Indianapolis

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

DelRicht Research of Indianapolis Clinical Trials

★ 4.8
2162 N Meridian St Ste B, Indianapolis, IN 46202
(504) 383-8674
"The staff is very helpful and attentive. Having a wonderful experience so far."
— Chrystopher Burns, 5★

Indiana CTSI

★ 4.0
410 W 10th St Ste 1000, Indianapolis, IN 46202
(317) 278-2874
"This is for the lawn outside. Chill spot to sit in the shade and relax for a moment. The mist from the spillway makes it feel relatively fresh and co…"
— Autumn McDonald, 4★

Stark Neurosciences Research Institute

★ 5.0
NB Building, 320 W 15th St #414, Indianapolis, IN 46202
(317) 278-7000
"Pretty neat building for the first time going inside, but a new hospital addition is being built next door which is 17 floors and should be finished …"
— Alex Hartman, 5★

Regenstrief Institute

★ 3.9
1101 W 10th St, Indianapolis, IN 46202
(317) 274-9000

Lilly Research Laboratories

★ 4.6
307 E Merrill St, Indianapolis, IN 46225
(317) 276-2000
"There was an issue with my mother's insulin pen today. She is visiting from out of state. She called and reported it and was attempting to requesting…"
— Michael Mannino, 1★

Indiana Alzheimer Disease Center

355 W 16th St, Indianapolis, IN 46202
(317) 963-5500

Indiana University Melvin and Bren Simon Comprehensive Cancer Center

★ 4.2 (59 reviews)
535 Barnhill Dr, Indianapolis, IN 46202
(888) 600-4822
"Worst experience. They don’t respect"
— Mike Smith, 1★

Indiana Center for Systems Biology and Personalized Medicine

★ 4.0
Walker Plaza, 719 Indiana Ave, Indianapolis, IN 46202
(317) 278-7604
"Do they store body parts here too. Like the research center in Chicago.?"
— El 701 Viajes Privados, 4★

IU Health Neuroscience Center

★ 3.8
355 W 15th St, Indianapolis, IN 46202
(317) 948-5450
"After 10 years of dealing with a brain tumor I made the decision to have it surgically removed by Neurosurgeon Dr Almeida. It was a complicated surge…"
— Dusty Roads, 5★

Clinical trials in Indianapolis: what's recruiting

The Indianapolis area currently has 915 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Indianapolis, the most active research areas are:

  • Cancer & Oncology4 studies
  • Diabetes & Metabolism3 studies
  • Liver & Kidney2 studies
  • Immune & Skin2 studies
  • Brain & Mental Health2 studies

Every listing shows the study phase, the recruiting site and its distance from Indianapolis, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Indianapolis

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Indianapolis participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Indianapolis pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
How do I join a study in Indianapolis, IN?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in Indianapolis?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Indianapolis.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Indianapolis typically complete one or two studies per year.

Paid clinical trials near Indianapolis

Other metros within reach

Lafayette, IN40 Fort Wayne, IN112 Louisville, KY576 Cincinnati, OH1,137 South Bend, IN113 Elkhart, IN113 Dayton, OH309 Champaign, IL167

More of IN

Elkhart113 South Bend113 Fort Wayne112 Evansville67 Lafayette40

New paid studies open every week

Get an email when a new clinical trial starts recruiting within 30 miles of your ZIP code. No spam — only real studies from the NIH registry.

By subscribing you agree to receive study alert emails. Unsubscribe anytime in one click.

Get free trial alerts