Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/IL/Champaign
Updated September 2026 from ClinicalTrials.gov

Paid Clinical Trials in Champaign, IL

Studies commonly pay $75 to $4,500 per completed study

170 clinical trials are currently recruiting participants within 30 miles of Champaign. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

170studies recruiting
9+research centers nearby
4condition categories
Live from the NIH registry

Studies recruiting near Champaign right now

Top 25 of 170 recruiting studies, sorted by proximity — each links to its official registry page

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

Endometrial Adenocarcinoma, Endometrial Clear Cell Adenocarcinoma Phase 2 Interventional 81 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05112601)

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8 Phase 3 Interventional 1,209 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05946213)

A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

Non-Small Cell Lung Cancer (NSCLC) Phase 3 Interventional 750 participants sought
Local Institution - 0423 — Urbana, Illinois (3.5 mi) · Sponsor: Bristol-Myers Squibb
See eligibility & contact on ClinicalTrials.gov (NCT07361510)

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

Malignant Female Reproductive System Neoplasm, Malignant Solid Neoplasm Phase 2 Interventional 70 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06126276)

High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma, Stage I Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8 Phase 3 Interventional 228 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06992427)

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

Metastatic Clear Cell Renal Cell Carcinoma, Metastatic Renal Cell Carcinoma Phase 3 Interventional 364 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT04510597)

Fall Prevention Among People With Spinal Cord Injury and Multiple Sclerosis Who Use Wheelchairs and Scooters

Spinal Cord Injuries (SCI), Multiple Sclerosis N/A Interventional 120 participants sought
Disability Participation and Quality of Life (DPQOL) Laboratory — Urbana, Illinois (3.5 mi) · Sponsor: University of Illinois at Urbana-Champaign
See eligibility & contact on ClinicalTrials.gov (NCT07167680)

Comparing Telephone Symptom Monitoring Interventions for Managing Symptoms and Psychological Distress During Oral Anti-Cancer Treatment

Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm N/A Interventional 600 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06279013)

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

Multiple conditions Phase 2 Interventional 98 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06532279)

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

Metastatic Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8 Phase 2 Interventional 240 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05327686)

Study Adding Drugs to Usual Treatment for Large B-Cell Lymphoma That Returned or Did Not Respond to Treatment

Grade 3b Follicular Lymphoma, High Grade B-Cell Lymphoma Phase 2 Interventional 227 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT05890352)

Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study Employing a Within-Subject Design

Alcohol Drinking, Alcohol Use Disorder (AUD) N/A Interventional 200 participants sought
University of Illinois at Urbana Champaign — Champaign, Illinois (1.6 mi) · Sponsor: University of Illinois at Urbana-Champaign
See eligibility & contact on ClinicalTrials.gov (NCT07125534)

Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer

Locally Advanced Hepatocellular Carcinoma, Metastatic Hepatocellular Carcinoma Phase 2 Interventional 122 participants sought
Carle Cancer Center NCI Community Oncology Research Program — Urbana, Illinois (3.5 mi) · Sponsor: Academic and Community Cancer Research United
See eligibility & contact on ClinicalTrials.gov (NCT05168163)

Maternal Mindfulness: Depression and Postpartum Pain

Depression, Unipolar, Pain, Postoperative N/A Interventional 75 participants sought
University of Illinois Urbana-Champaign — Champaign, Illinois (1.6 mi) · Sponsor: University of Illinois at Urbana-Champaign
See eligibility & contact on ClinicalTrials.gov (NCT05400382)

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 Phase 3 Interventional 3,680 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06058377)

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

Locally Advanced Cervical Adenocarcinoma, Locally Advanced Cervical Adenosquamous Carcinoma Phase 3 Interventional 336 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT07061977)

Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change

Advanced Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell Carcinoma Phase 2 Interventional 46 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT03191149)

An Individualized-health eLibrary App for People With Multiple Sclerosis

Multiple Sclerosis N/A Interventional 60 participants sought
University of Illinois Urbana-Champaign — Champaign, Illinois (1.6 mi) · Sponsor: University of Illinois at Urbana-Champaign
See eligibility & contact on ClinicalTrials.gov (NCT05124600)

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

Advanced Colorectal Carcinoma, Advanced Lung Non-Small Cell Carcinoma N/A Observational 800 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: University of Rochester
See eligibility & contact on ClinicalTrials.gov (NCT06073431)

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma, Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7 Phase 2, Phase 3 Interventional 613 participants sought
Carle Cancer Center — Urbana, Illinois (3.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT01810913)

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

Endometrial Cancer, Malignant Solid Tumour Phase 3 Interventional 800 participants sought
Research Site — Urbana, Illinois (3.5 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07044336)
Actively enrolling

Studies you may be able to join near Champaign

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Champaign

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Cline Center for Advanced Social Research

★ 3.7
2001 S 1st St Ste 207, Champaign, IL 61820
(217) 265-7845

Christie Clinic Clinical Research

1801 W Windsor Rd, Champaign, IL 61822
(217) 366-2200

Alcohol Research Lab

Psychology Building, 603 E Daniel St Room 23, Champaign, IL 61820
(217) 300-5850

Coordinated Science Laboratory

★ 4.6
1308 W Main St Rm B16, Urbana, IL 61801
(217) 333-2511
"Lots of offices and an auditorium."
— Dave Vesely, 4★

U of I Urbana-Champaign Cancer Center at Illinois

Beckman Institute for Advanced Science and Technology, 405 N Mathews Ave, Urbana, IL 61801
(217) 300-6100

University of Illinois Counseling Center

★ 2.4 (18 reviews)
610 E John St Rm 206, Champaign, IL 61820
(217) 333-3704
"Absurd contract they try to get you to sign which puts everything against the student seeking help. They pretend to not know any better. Ludicrous."
— John B, 1★

Carle Cancer Institute Urbana

★ 4.3
509 W University Ave, Urbana, IL 61801
(217) 383-3010

Christie Clinic Department of Dermatology- Cosmetic Center

★ 4.3
101 W University Ave, Champaign, IL 61820
(217) 366-1248

Carle Neuroscience Institute

★ 3.5
610 N Lincoln Ave, Urbana, IL 61801
(217) 383-6555
"It's clean, and seemed quiet. I had a great doctor that listened to me. The front desk staff seemed respectful."
— Samantha Ragazincky, 5★

Clinical trials in Champaign: what's recruiting

The Champaign area currently has 170 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Champaign, the most active research areas are:

  • Cancer & Oncology17 studies
  • Liver & Kidney3 studies
  • Lungs & Breathing1 studies
  • Brain & Mental Health1 studies

Every listing shows the study phase, the recruiting site and its distance from Champaign, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Champaign

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Champaign participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Champaign?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Champaign?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Champaign?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Champaign.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Champaign typically complete one or two studies per year.

Paid clinical trials near Champaign

Other metros within reach

Joliet, IL515 Springfield, IL182 Lafayette, IN36 Peoria, IL218 Naperville, IL2,346 Aurora, IL614 Chicago, IL2,431 Indianapolis, IN928

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Champaign Bladder Issues Due To Spinal Cord Injury in Champaign All conditions

More of IL

Chicago2,431 Naperville2,346 Aurora614 Joliet515 Round Lake Beach465 Peoria218 Springfield182 Rockford112

New paid studies open every week

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