How much do paid clinical trials in South Bend pay?

Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.

Are clinical trials in South Bend safe?

Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.

What is the difference between a research center and a hospital study in South Bend?

Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.

How often do new paid studies open in South Bend?

Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of South Bend.

Can I be in more than one clinical trial at a time?

Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in South Bend typically complete one or two studies per year.

Paid Clinical Trials South Bend, IN — 113 Studies Recruiting (Jul 2026)

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Multiple conditions Phase 2 Interventional 150 participants sought

Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan (10.6 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT05136196)

Safety and Efficacy of APC-0101 in Preterm Infants With Respiratory Distress Syndrome

Respiratory Distress Syndrome, Pre-term Infants Phase 3 Interventional 520 participants sought

Memorial Hospital of South Bend — South Bend, Indiana (1.1 mi) · Sponsor: Aerogen Pharma Limited

See eligibility & contact on ClinicalTrials.gov (NCT06776783)

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

Plasma Cell Myeloma, RISS Stage I Plasma Cell Myeloma Phase 3 Interventional 1,450 participants sought

Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan (10.6 mi) · Sponsor: ECOG-ACRIN Cancer Research Group

See eligibility & contact on ClinicalTrials.gov (NCT04566328)

Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

Classic Follicular Lymphoma, Follicular Lymphoma With Unusual Cytological Features Phase 3 Interventional 600 participants sought

Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan (10.6 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT06337318)

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

Advanced Endometrial Carcinoma, Recurrent Endometrial Carcinoma Phase 3 Interventional 255 participants sought

Memorial Hospital of South Bend — South Bend, Indiana (1.1 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT07198074)

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma, Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7 Phase 2, Phase 3 Interventional 613 participants sought

Memorial Hospital of South Bend — South Bend, Indiana (1.1 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT01810913)

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Ovarian Carcinoma N/A Interventional 1,956 participants sought

Goshen Center for Cancer Care — Goshen, Indiana (23.4 mi) · Sponsor: NRG Oncology

See eligibility & contact on ClinicalTrials.gov (NCT04251052)

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

Metastatic Malignant Neoplasm in the Lung, Metastatic Osteosarcoma Phase 3 Interventional 62 participants sought

Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan (10.6 mi) · Sponsor: Children's Oncology Group

See eligibility & contact on ClinicalTrials.gov (NCT05235165)

Restorative Effects of Sleep on Everyday Health and Wellbeing: A Treatment Study

Chronic Insomnia N/A Interventional 115 participants sought

University of Notre Dame — Notre Dame, Indiana (2.3 mi) · Sponsor: University of Notre Dame

See eligibility & contact on ClinicalTrials.gov (NCT07156383)

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

Stage I Breast Cancer Phase 3 Interventional 1,670 participants sought

Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan (10.6 mi) · Sponsor: NRG Oncology

See eligibility & contact on ClinicalTrials.gov (NCT04852887)

Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

Breast Cancer, Cognitive Impairments N/A Interventional 386 participants sought

Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan (10.6 mi) · Sponsor: NRG Oncology

See eligibility & contact on ClinicalTrials.gov (NCT05896189)

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

Intracranial Meningioma, Recurrent Meningioma Phase 2 Interventional 124 participants sought

Memorial Hospital of South Bend — South Bend, Indiana (1.1 mi) · Sponsor: Alliance for Clinical Trials in Oncology

See eligibility & contact on ClinicalTrials.gov (NCT02523014)

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

NASH With Fibrosis, MASH With Fibrosis Phase 3 Interventional 1,650 participants sought

Akero Clinical Study Site — South Bend, Indiana (1.1 mi) · Sponsor: Akero Therapeutics, Inc

See eligibility & contact on ClinicalTrials.gov (NCT06215716)

Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

Metastatic Lung Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Brain Phase 3 Interventional 200 participants sought

Goshen Center for Cancer Care — Goshen, Indiana (23.4 mi) · Sponsor: NRG Oncology

See eligibility & contact on ClinicalTrials.gov (NCT04804644)

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 Phase 3 Interventional 3,680 participants sought

Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan (10.6 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT06058377)

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Lung Non-Small Cell Carcinoma, Lung Non-Small Cell Squamous Carcinoma Phase 3 Interventional 1,210 participants sought

Memorial Hospital of South Bend — South Bend, Indiana (1.1 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT04267848)

ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 Phase 3 Interventional 1,524 participants sought

Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan (10.6 mi) · Sponsor: Alliance for Clinical Trials in Oncology

See eligibility & contact on ClinicalTrials.gov (NCT06876714)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought

Memorial Hospital of South Bend — South Bend, Indiana (1.1 mi) · Sponsor: SWOG Cancer Research Network

See eligibility & contact on ClinicalTrials.gov (NCT03851445)

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

Advanced Lung Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8 Phase 3 Interventional 304 participants sought

Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan (10.6 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT06096844)

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

Multiple conditions N/A Observational 2,000 participants sought

Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan (10.6 mi) · Sponsor: Alliance for Clinical Trials in Oncology

See eligibility & contact on ClinicalTrials.gov (NCT05334069)

Collection and Storage of Tissue and Blood Samples From Patients With Cancer

Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm N/A Observational 5,000 participants sought

Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan (10.6 mi) · Sponsor: National Cancer Institute LAO

See eligibility & contact on ClinicalTrials.gov (NCT02474160)

The Happy Families Project: Testing the Effectiveness of a Conflict Resolution Program for Families

Mental Health, Conflict N/A Interventional 1,800 participants sought

University of Notre Dame — Notre Dame, Indiana (2.3 mi) · Sponsor: University of Notre Dame

See eligibility & contact on ClinicalTrials.gov (NCT04980794)

Study to Evaluate HM15275 in Subjects With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus, T2DM Phase 2 Interventional 180 participants sought

The South Bend Clinic — South Bend, Indiana (1.1 mi) · Sponsor: Hanmi Pharmaceutical Company Limited

See eligibility & contact on ClinicalTrials.gov (NCT07527650)

Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

Aortic Stenosis, Coronary Artery Disease N/A Interventional 4,000 participants sought

Midwest Cardiovascular Research and Education Foundation — Elkhart, Indiana (15.1 mi) · Sponsor: University of British Columbia

See eligibility & contact on ClinicalTrials.gov (NCT04634240)

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

Muscle Invasive Bladder Urothelial Carcinoma, Muscle Invasive Renal Pelvis Urothelial Carcinoma Phase 2, Phase 3 Interventional 992 participants sought

Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan (10.6 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT05987241)

Paid Clinical Trials in South Bend, IN

Studies recruiting near South Bend right now

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Safety and Efficacy of APC-0101 in Preterm Infants With Respiratory Distress Syndrome

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

Restorative Effects of Sleep on Everyday Health and Wellbeing: A Treatment Study

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

Collection and Storage of Tissue and Blood Samples From Patients With Cancer

The Happy Families Project: Testing the Effectiveness of a Conflict Resolution Program for Families

Study to Evaluate HM15275 in Subjects With Type 2 Diabetes Mellitus

Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

Top-rated research centers in South Bend

Center for Rare and Neglected Diseases

Digestive Research Alliance of Michiana

Notre Dame Clinical Law Center

Velocity Clinical Research

Cardinal Recovery

Medical Behavioral Hospital of Mishawaka

Physicians HolisticHealth Alliance

LūM Granger

Chicago Clinical Research Institute, Inc.

Clinical trials in South Bend: what's recruiting

How to enroll in a paid study in South Bend

Frequently asked questions

Paid clinical trials near South Bend

More of IN

New paid studies open every week