Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/KY/Lexington
Updated July 2026 from ClinicalTrials.gov

Paid Clinical Trials in Lexington, KY

Studies commonly pay $75 to $4,500 per completed study

467 clinical trials are currently recruiting participants within 30 miles of Lexington. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

467studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Lexington right now

Top 25 of 467 recruiting studies, sorted by proximity — each links to its official registry page

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

Neovascular Age-related Macular Degeneration Phase 4 Interventional 188 participants sought
Retina Associates of Kentucky — Lexington, Kentucky (3.8 mi) · Sponsor: Genentech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04853251)

A Study to Evaluate DJI136, a DLL3-targeted CAR-T Therapy

Extensive-stage Small Cell Lung Cancer (ES-SCLC) Phase 1, Phase 2 Interventional 80 participants sought
University of Kentucky — Lexington, Kentucky (3.8 mi) · Sponsor: Novartis Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT07564401)

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Recurrent Head and Neck Squamous Cell Carcinoma, Recurrent Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 188 participants sought
University of Kentucky/Markey Cancer Center — Lexington, Kentucky (3.8 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04671667)

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

Brain Cancer, Breast Cancer N/A Observational 7,000 participants sought
Baptist Lexington — Lexington, Kentucky (3.8 mi) · Sponsor: Adela, Inc
See eligibility & contact on ClinicalTrials.gov (NCT05366881)

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Ganglioneuroblastoma, Nodular, Neuroblastoma Phase 3 Interventional 478 participants sought
University of Kentucky/Markey Cancer Center — Lexington, Kentucky (3.8 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06172296)

Hydrocolloid Dressings for Oculofacial Plastic and Reconstructive Wound Healing

Wound Healing, Mohs Micrographic Surgery N/A Interventional 20 participants sought
University of Kentucky — Lexington, Kentucky (3.8 mi) · Sponsor: Janice Hernandez, MD
See eligibility & contact on ClinicalTrials.gov (NCT07075159)

A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)

Staphylococcus Aureus Phase 1, Phase 2 Interventional 231 participants sought
Research Site — Lexington, Kentucky (3.8 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06749457)

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

Plasma Cell Myeloma, RISS Stage I Plasma Cell Myeloma Phase 3 Interventional 1,450 participants sought
Saint Joseph Hospital — Lexington, Kentucky (3.8 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT04566328)

MOntelukast as a Potential CHondroprotective Treatment Following Anterior Cruciate Ligament Reconstruction (MOCHA Trial)

ACL Injury, Meniscus Tear EARLY/Phase 1 Interventional 30 participants sought
UK Healthcare at Turfland — Lexington, Kentucky (3.8 mi) · Sponsor: Austin V Stone
See eligibility & contact on ClinicalTrials.gov (NCT04572256)

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

Metastatic Castration-resistant Prostate Cancer (mCRPC), Prostatic Neoplasms Phase 3 Interventional 1,314 participants sought
University of Kentucky Chandler Medical Center ( Site 0048) — Lexington, Kentucky (3.8 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06136650)

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

Advanced Endometrial Carcinoma, Recurrent Endometrial Carcinoma Phase 3 Interventional 255 participants sought
University of Kentucky/Markey Cancer Center — Lexington, Kentucky (3.8 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT07198074)

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Phase 2 Interventional 2,000 participants sought
University of Kentucky/Markey Cancer Center — Lexington, Kentucky (3.8 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05564390)

Intracept Minimally-invasive PROcedure for VErtebrogenic Back Pain

Chronic Low-back Pain, Vertebrogenic Pain Syndrome N/A Observational 1,500 participants sought
Commonwealth Pain and Spine — Lexington, Kentucky (3.8 mi) · Sponsor: Boston Scientific Corporation
See eligibility & contact on ClinicalTrials.gov (NCT06827262)

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Breast Cancer, Early Breast Cancer Phase 3 Interventional 4,300 participants sought
Research Site — Lexington, Kentucky (3.8 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT05774951)

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma, Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7 Phase 2, Phase 3 Interventional 613 participants sought
University of Kentucky/Markey Cancer Center — Lexington, Kentucky (3.8 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT01810913)

A Global Study Comparing Pulsed Field Ablation With Electrographic Flow Mapping Versus Posterior Wall Ablation for Persistent Atrial Fibrillation

Atrial Fibrillation (AF), Persistant Atrial Fibrillation N/A Interventional 699 participants sought
Baptist Health Lexington — Lexington, Kentucky (3.8 mi) · Sponsor: Boston Scientific Corporation
See eligibility & contact on ClinicalTrials.gov (NCT07187115)

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Ovarian Carcinoma N/A Interventional 1,956 participants sought
Baptist Health Lexington — Lexington, Kentucky (3.8 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04251052)

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

Metastatic Malignant Neoplasm in the Lung, Metastatic Osteosarcoma Phase 3 Interventional 62 participants sought
University of Kentucky/Markey Cancer Center — Lexington, Kentucky (3.8 mi) · Sponsor: Children's Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT05235165)

Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

Recurrent B Acute Lymphoblastic Leukemia, Recurrent B Lymphoblastic Lymphoma Phase 2 Interventional 80 participants sought
University of Kentucky/Markey Cancer Center — Lexington, Kentucky (3.8 mi) · Sponsor: Children's Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT02981628)
Google-rated

Top-rated research centers in Lexington

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Baptist Health Lexington Clinical Research Center

★ 5.0
1740 Nicholasville Rd, Lexington, KY 40503
(859) 260-3720

UK Center for Clinical and Translational Science (CCTS)

800 Rose St Rm C300, Lexington, KY 40508
(859) 323-2615

Sports Medicine Research Institute

★ 3.0
720 Sports Center Dr, Lexington, KY 40506
(859) 323-9850

AMR - Lexington (Alliance for Multispecialty Research)

★ 4.4
3475 Richmond Rd 3rd Floor, Lexington, KY 40509
(859) 264-8999
"Participated in a study 2 weeks ago and could not have been treated more professionally. Atmosphere was beautiful, calm and welcoming. Staff was fri…"
— Victoria Duvall, 5★

UK Precision Medicine Clinic

800 Rose St Second Floor, Suite HX200, Room HX 235, Lexington, KY 40536
(859) 323-7372

Healthy Kentucky Research Building

★ 5.0
760 Press Ave, Lexington, KY 40508
(859) 323-6108

Kentucky Clinical Trials Network

2365 Harrodsburg Rd, Lexington, KY 40504
(859) 323-1109

University of Kentucky Research Foundation

Kinkead Hall, 201 Kinkead Hall, Lexington, KY 40508
(859) 257-8311

Institute for Biomedical Informatics (IBI) at the University of Kentucky

University of Kentucky, Institute for Biomedical Informatics, Multidisciplinary Science, 725 Rose St Building, suite 230, Lexington, KY 40536

Clinical trials in Lexington: what's recruiting

The Lexington area currently has 467 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Lexington, the most active research areas are:

  • Cancer & Oncology14 studies
  • Brain & Mental Health2 studies
  • Heart & Vascular1 studies
  • Liver & Kidney1 studies
  • Immune & Skin1 studies

Every listing shows the study phase, the recruiting site and its distance from Lexington, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Lexington

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Lexington participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Lexington pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Do I need to be sick to join a clinical trial in Lexington?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Are clinical trials in Lexington safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Lexington, KY?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
How often do new paid studies open in Lexington?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Lexington.

Paid clinical trials near Lexington

Other metros within reach

Cincinnati, OH1,137 Louisville, KY576 Dayton, OH309 Huntington, WV58 Knoxville, TN223 Indianapolis, IN915 Columbus, OH1,325 Murfreesboro, TN79

More of KY

Louisville576

New paid studies open every week

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