Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/TN/Nashville
Updated July 2026 from ClinicalTrials.gov

Paid Clinical Trials in Nashville, TN

Studies commonly pay $75 to $4,500 per completed study

1,336 clinical trials are currently recruiting participants within 30 miles of Nashville. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

1,336studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Nashville right now

Top 25 of 1,336 recruiting studies, sorted by proximity — each links to its official registry page

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
Tennessee Oncology, PLLC — Nashville, Tennessee (0.4 mi) · Sponsor: Relay Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06982521)

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

Neovascular Age-related Macular Degeneration Phase 4 Interventional 188 participants sought
Tennessee Retina PC — Nashville, Tennessee (0.4 mi) · Sponsor: Genentech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04853251)

Study to Evaluate the Safety and Tolerability of Camizestrant in Combination With Atirmociclib in Women With Advanced Breast Cancer

Advanced Breast Cancer Phase 2 Interventional 24 participants sought
Research Site — Nashville, Tennessee (0.4 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07427394)

Comparing Healthcare Visit Recording and Open Notes to Improve Chronic iLlness Care Experience in Older Adults

Diabetes Mellitus, Hypertension N/A Interventional 1,022 participants sought
Vanderbit University Medical Center — Nashville, Tennessee (0.4 mi) · Sponsor: Dartmouth-Hitchcock Medical Center
See eligibility & contact on ClinicalTrials.gov (NCT05955339)

A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies

Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL) Phase 1 Interventional 248 participants sought
Tennessee Oncology — Nashville, Tennessee (0.4 mi) · Sponsor: Nurix Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04830137)

Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures: A Pragmatic, Randomized Controlled Trial

Tibial Fractures, Pain Phase 3 Interventional 1,000 participants sought
Vanderbilt Medical Center — Nashville, Tennessee (0.4 mi) · Sponsor: Major Extremity Trauma Research Consortium
See eligibility & contact on ClinicalTrials.gov (NCT07006675)

Study of Momelotinib in Combination With Luspatercept in Participants With Transfusion Dependent Myelofibrosis

Primary Myelofibrosis, Myelofibrosis; Primary Myelofibrosis; Post-polycythemia Vera Myelofibrosis; Post-essential Thrombocythemia Myelofibrosis Phase 2 Interventional 68 participants sought
GSK Investigational Site — Nashville, Tennessee (0.4 mi) · Sponsor: GlaxoSmithKline
See eligibility & contact on ClinicalTrials.gov (NCT06517875)

Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder Cancer 2

Bladder Cancer, Recurrent Bladder Cancer N/A Observational 408 participants sought
Vanderbilt University Medical Center — Nashville, Tennessee (0.4 mi) · Sponsor: University of Washington
See eligibility & contact on ClinicalTrials.gov (NCT07225127)

A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy

Geographic Atrophy, Macular Degeneration N/A Observational 500 participants sought
Tennessee Retina, PC — Nashville, Tennessee (0.4 mi) · Sponsor: Astellas Pharma Global Development, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06779773)

Prevention of Intradialytic Hypotension by Inhibiting Bradykinin B2 Receptor

Intradialytic Hypotension Phase 3 Interventional 26 participants sought
Vanderbilt Fresenius — Nashville, Tennessee (0.4 mi) · Sponsor: Vanderbilt University Medical Center
See eligibility & contact on ClinicalTrials.gov (NCT05834777)

Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies

Advanced Solid Tumor, Metastatic Solid Tumor Phase 1 Interventional 220 participants sought
Sarah Cannon Research Institute — Nashville, Tennessee (0.4 mi) · Sponsor: Circle Pharma
See eligibility & contact on ClinicalTrials.gov (NCT06577987)

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

Carcinoma, Non-Small Cell Lung, Squamous Cell Carcinoma of Head and Neck Phase 1 Interventional 1,006 participants sought
US Oncology Research LLC — Nashville, Tennessee (0.4 mi) · Sponsor: Seagen, a wholly owned subsidiary of Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT04389632)

Study of JANX014 in Subjects With Metastatic Castration-Resistant Prostate Cancer

Prostate Cancer, Metastatic Castration-resistant Prostate Cancer Phase 1 Interventional 43 participants sought
Research Site — Nashville, Tennessee (0.4 mi) · Sponsor: Janux Therapeutics
See eligibility & contact on ClinicalTrials.gov (NCT07545811)

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Recurrent Head and Neck Squamous Cell Carcinoma, Recurrent Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 188 participants sought
Vanderbilt University/Ingram Cancer Center — Nashville, Tennessee (0.4 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04671667)

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

Brain Cancer, Breast Cancer N/A Observational 7,000 participants sought
Vanderbilt-Ingram Cancer Center — Nashville, Tennessee (0.4 mi) · Sponsor: Adela, Inc
See eligibility & contact on ClinicalTrials.gov (NCT05366881)

Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia

B-cell Acute Lymphoblastic Leukemia (B-ALL) Phase 1, Phase 2 Interventional 83 participants sought
Research Site — Franklin, Tennessee (17.7 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07109219)

Real-World Data Collection of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis When Used in Covered Endovascular Reconstruction of the Aortic Bifurcation (CERAB) to Treat Aortoiliac Occlusive Disease

Aortoiliac Occlusive Disease N/A Observational 158 participants sought
Vanderbilt University Medical Center — Nashville, Tennessee (0.4 mi) · Sponsor: W.L.Gore & Associates
See eligibility & contact on ClinicalTrials.gov (NCT06872905)

Cooperative Assessment of Late Effects for SCD Curative Therapies

Sickle Cell Disease, Pulmonary Disease N/A Observational 750 participants sought
Vanderbilt University Medical Center — Nashville, Tennessee (0.4 mi) · Sponsor: Vanderbilt University Medical Center
See eligibility & contact on ClinicalTrials.gov (NCT05153967)

XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)

Heart Transplant, Heart Failure N/A Interventional 60 participants sought
Vanderbilt University Medical Center — Nashville, Tennessee (0.4 mi) · Sponsor: XVIVO Perfusion
See eligibility & contact on ClinicalTrials.gov (NCT06895070)

A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)

Relapsed Refractory Multiple Myeloma Phase 3 Interventional 508 participants sought
Research Site — Nashville, Tennessee (0.4 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07391657)

Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors

Solid Tumor, Advanced Cancer Phase 1 Interventional 330 participants sought
Vanderbilt-Ingram Cancer Center — Nashville, Tennessee (0.4 mi) · Sponsor: I-Mab Biopharma US Limited
See eligibility & contact on ClinicalTrials.gov (NCT04900818)
Google-rated

Top-rated research centers in Nashville

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Vanderbilt Clinical Research Center

★ 5.0
1161 21st Ave S Suite 2400, Nashville, TN 37232
(615) 322-2312

Clinical Research Associates Inc

★ 4.7
1500 Church St, Nashville, TN 37203
(615) 329-0197
"Incredible staff! Efficient, friendly, helpful…. I’ve had so much fun! Apply to be a participant today!"
— Curtis B, 5★

Tennessee Clinical Research

★ 3.8
2000 Richard Jones Rd #223, Nashville, TN 37215
(615) 383-9660
"I have nothing to compare to ,I have not tried anything for my hair loss as of yet.It was easy filling out the questions and ,when and if I get to pa…"
— Sajadia Gonzalez, 3★

Greco-Hainsworth Centers for Research - DDU

322 22nd Ave N Ste 300, Nashville, TN 37203
(615) 460-3825

Sarah Cannon Research Institute

★ 4.4 (26 reviews)
250 25th Ave N, Nashville, TN 37203
(615) 329-7274
"The oncologist is first rate. The facility/staffing is not. One would think that a facility dedicated to treatment for people with compromised immune…"
— J H, 3★

SCRI Oncology Partners

★ 4.9 (262 reviews)
335 24th Ave N #200, Nashville, TN 37203
(615) 329-7640
"I do not recommend going here. I started with this oncology practice after being diagnosed with breast cancer. What I don't like is their appointment…"
— dageminii05 Gogirl, 2★

Medical Research Building III

★ 5.0
465 21st Ave S, Nashville, TN 37232

TriStar Centennial Medical Center

★ 4.6
2300 Patterson St, Nashville, TN 37203
(615) 342-1000

Preston Cancer Research Building Vanderbilt University Medical Center

★ 5.0
2220 Pierce Ave, Nashville, TN 37232
(615) 936-8422
"Amazing service! It’s not exactly where I want to be, but they do an excellent job of being hospitable."
— TRACIE ROBINSON, 5★

Clinical trials in Nashville: what's recruiting

The Nashville area currently has 1,336 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Nashville, the most active research areas are:

  • Cancer & Oncology13 studies
  • Heart & Vascular4 studies
  • Liver & Kidney2 studies
  • Brain & Mental Health1 studies
  • Diabetes & Metabolism1 studies

Every listing shows the study phase, the recruiting site and its distance from Nashville, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Nashville

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Nashville participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Nashville?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
How do I join a study in Nashville, TN?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Nashville?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Nashville?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Nashville.

Paid clinical trials near Nashville

Other metros within reach

Murfreesboro, TN79 Clarksville, TN9 Huntsville, AL86 Chattanooga, TN146 Evansville, IN67 Louisville, KY576 Birmingham, AL962 Knoxville, TN223

More of TN

Memphis578 Knoxville223 Chattanooga146 Murfreesboro79 Clarksville9

New paid studies open every week

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