Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/SC/Greenville
Updated July 2026 from ClinicalTrials.gov

Paid Clinical Trials in Greenville, SC

Studies commonly pay $75 to $4,500 per completed study

382 clinical trials are currently recruiting participants within 30 miles of Greenville. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

382studies recruiting
9+research centers nearby
3condition categories
Live from the NIH registry

Studies recruiting near Greenville right now

Top 25 of 382 recruiting studies, sorted by proximity — each links to its official registry page

Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection

Viral Pneumonia Phase 2 Interventional 550 participants sought
AnMed Health Pulmonary and Sleep Medicine — Anderson, South Carolina (28.1 mi) · Sponsor: Synairgen Research Ltd.
See eligibility & contact on ClinicalTrials.gov (NCT06999603)

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

Amyloidosis, Amyloid Cardiomyopathy Phase 3 Interventional 587 participants sought
Prisma Health Cancer Institute — Greenville, South Carolina (2.0 mi) · Sponsor: Eidos Therapeutics, a BridgeBio company
See eligibility & contact on ClinicalTrials.gov (NCT06563895)

Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML

Hematologic Malignancies Phase 1, Phase 2 Interventional 160 participants sought
Bon Secours St. Francis Cancer Center — Greenville, South Carolina (2.0 mi) · Sponsor: Sellas Life Sciences Group
See eligibility & contact on ClinicalTrials.gov (NCT04588922)

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

Systemic Lupus Erythematosus Phase 3 Interventional 100 participants sought
Research Site — Greenville, South Carolina (2.0 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT05835310)

Comparing Telephone Symptom Monitoring Interventions for Managing Symptoms and Psychological Distress During Oral Anti-Cancer Treatment

Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm N/A Interventional 600 participants sought
Prisma Health Cancer Institute - Butternut — Greenville, South Carolina (2.0 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06279013)

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Ganglioneuroblastoma, Nodular, Neuroblastoma Phase 3 Interventional 478 participants sought
BI-LO Charities Children's Cancer Center — Greenville, South Carolina (2.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06172296)

A Safety and Efficacy Study of HCB101, Fc-fusion Protein Targeting SIRPα-CD47 Pathway, in Solid or Hematological Tumors

Advanced Solid Tumor, Refractory Non-Hodgkin Lymphoma Phase 1 Interventional 80 participants sought
Greenville Hospital System University Medical Center (ITOR) — Greenville, South Carolina (2.0 mi) · Sponsor: FBD Biologics Limited
See eligibility & contact on ClinicalTrials.gov (NCT05892718)

Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)

Acute Myeloid Leukemia Phase 2 Interventional 93 participants sought
Prisma Health Cancer Institute - Butternut — Greenville, South Carolina (2.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06672146)

Longitudinal Screening for Financial Hardship to Improve Outcomes in Patients With Advanced Cancer

Advanced Cancer, Metastatic Cancer N/A Interventional 1,000 participants sought
Gibbs Cancer Center — Spartanburg, South Carolina (25.8 mi) · Sponsor: Alliance Foundation Trials, LLC.
See eligibility & contact on ClinicalTrials.gov (NCT06963723)

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

Plasma Cell Myeloma, RISS Stage I Plasma Cell Myeloma Phase 3 Interventional 1,450 participants sought
Saint Francis Hospital — Greenville, South Carolina (2.0 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT04566328)

Study to Evaluate IMP9064 as a Monotherapy or in Combination in Patients With Advanced Solid Tumors

Solid Tumor, Advanced Solid Tumor Phase 1, Phase 2 Interventional 61 participants sought
Greenville Hospital System University Medical Center (ITOR) — Greenville, South Carolina (2.0 mi) · Sponsor: Impact Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05269316)

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Phase 2 Interventional 2,000 participants sought
Prisma Health Cancer Institute - Butternut — Greenville, South Carolina (2.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05564390)

Near Infrared Spectroscopy (NIRS) as a Method for Measuring Oxidative Capacity of Skeletal Muscle Mitochondria in Breast Cancer and All Gynecological Cancer Patients

Breast Cancer, Gynecologic Cancers N/A Observational 30 participants sought
Prisma Health Cancer Institute — Greenville, South Carolina (2.0 mi) · Sponsor: University of South Carolina
See eligibility & contact on ClinicalTrials.gov (NCT06672497)

An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors

Advanced Solid Tumor, Refractory Hodgkin Lymphoma Phase 1 Interventional 50 participants sought
Prisma Health-Upstate — Greenville, South Carolina (2.0 mi) · Sponsor: FBD Biologics Limited
See eligibility & contact on ClinicalTrials.gov (NCT06487624)

A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer Phase 2 Interventional 150 participants sought
Saint Francis Cancer Center - Greenville /ID# 276368 — Greenville, South Carolina (2.0 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06568939)

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Breast Cancer, Early Breast Cancer Phase 3 Interventional 4,300 participants sought
Research Site — Spartanburg, South Carolina (25.8 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT05774951)

Evaluation of Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN)

Primary Membranous Nephropathy Phase 2, Phase 3 Interventional 176 participants sought
Carolina Nephrology Greenville — Greenville, South Carolina (2.0 mi) · Sponsor: Vertex Pharmaceuticals Incorporated
See eligibility & contact on ClinicalTrials.gov (NCT07204275)

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma, Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7 Phase 2, Phase 3 Interventional 613 participants sought
Prisma Health Cancer Institute - Faris — Greenville, South Carolina (2.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT01810913)

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Ovarian Carcinoma N/A Interventional 1,956 participants sought
Prisma Health Cancer Institute - Faris — Greenville, South Carolina (2.0 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04251052)

Lot-to-lot Consistency Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From 2 Months of Age

Pneumococcal Immunization, Healthy Volunteers Phase 3 Interventional 2,195 participants sought
Parkside Pediatrics - Simpsonville- Site Number : 8400005 — Simpsonville, South Carolina (9.2 mi) · Sponsor: Sanofi
See eligibility & contact on ClinicalTrials.gov (NCT07348692)

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

Metastatic Malignant Neoplasm in the Lung, Metastatic Osteosarcoma Phase 3 Interventional 62 participants sought
BI-LO Charities Children's Cancer Center — Greenville, South Carolina (2.0 mi) · Sponsor: Children's Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT05235165)
Google-rated

Top-rated research centers in Greenville

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Tribe Clinical Research

★ 4.9
545 Verdae Blvd Ste B, Greenville, SC 29607
(864) 334-0141
"The staff here makes sure you are well informed and comfortable with the trial that you are participating in. Questions are welcomed and answered In …"
— amy bellis, 5★

Palmetto Clinical Trial Services, LLC

37 Brendan Way, Greenville, SC 29615
(864) 214-1217

The Research Center of the Upstate

★ 5.0
2086 Woodruff Rd, Greenville, SC 29607
(864) 626-3117
"Amazing and knowledgeable staff. Research program much needed in our local community."
— Victor & Rene' Pressley, 5★

Institute for Translational Oncology Research

900 W Faris Rd, Greenville, SC 29605
(864) 455-3600

ADAC Research, PA

★ 3.5
1202 E Butler Rd, Greenville, SC 29607
(864) 627-3800 ext. 221
"They were rude and you have to set a timer your self,and they dropped the cotton swabs in the trash,and still put the creem on with the contaminated …"
— Kippy Sloan, 1★

Prisma Health Cancer Institute–Faris Road

★ 3.4 (17 reviews)
900 W Faris Rd, Greenville, SC 29605
(864) 679-3900
"I’ve left so many messages and never a response until it’s time for chemo. If I do reach a live person, then they transfer me to another voicemail. I…"
— ASG Nesmith, 1★

Brio Primary Care

★ 4.8
2 Bella Grove Dr, Greenville, SC 29607
(864) 603-5600

Prisma Health Cancer Institute–Eastside

★ 4.2 (25 reviews)
65 International Dr, Greenville, SC 29615
(864) 987-7000
"At check in i almost passed out. AMY AND VIRGINA at the front desk came and prevented me from falling. They got me a wheel chair and made sure I was …"
— Adrea Webster, 5★

Infused Greenville, Greenville Ketamine Center

★ 4.8
35 Creekview Ct, Greenville, SC 29615
(864) 438-1300
"Absolutely amazing! The staff was so courteous and sweet, but most of all, and most importantly, medically skilled! From the nurse practitioners to t…"
— April King, 5★

Clinical trials in Greenville: what's recruiting

The Greenville area currently has 382 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Greenville, the most active research areas are:

  • Cancer & Oncology14 studies
  • Heart & Vascular2 studies
  • Immune & Skin2 studies

Every listing shows the study phase, the recruiting site and its distance from Greenville, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Greenville

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Greenville participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Greenville pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Do I need to be sick to join a clinical trial in Greenville?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Greenville?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Greenville?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Greenville.

Paid clinical trials near Greenville

Other metros within reach

Mauldin, SC382 Spartanburg, SC367 Asheville, NC121 Gastonia, NC650 Athens, GA69 Rock Hill, SC587 Hickory, NC92 Augusta, GA184

More of SC

Charleston734 Rock Hill587 Mauldin382 Spartanburg367 Columbia201 Myrtle Beach86

New paid studies open every week

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