Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/SC/Columbia
Updated July 2026 from ClinicalTrials.gov

Paid Clinical Trials in Columbia, SC

Studies commonly pay $75 to $4,500 per completed study

201 clinical trials are currently recruiting participants within 30 miles of Columbia. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

201studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Columbia right now

Top 25 of 201 recruiting studies, sorted by proximity — each links to its official registry page

Improving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads

SARS- CoV-2, Cardiovascular Diseases N/A Interventional 500 participants sought
University of South Carolina — Columbia, South Carolina (7.9 mi) · Sponsor: University of South Carolina
See eligibility & contact on ClinicalTrials.gov (NCT05370014)

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

Neovascular Age-related Macular Degeneration Phase 4 Interventional 188 participants sought
Palmetto Retina Center, LLC — West Columbia, South Carolina (10.2 mi) · Sponsor: Genentech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04853251)

Family-Centered Implementation of Parent Training for Autistic Toddlers in Early Intervention

Autism N/A Interventional 40 participants sought
University of South Carolina — Columbia, South Carolina (7.9 mi) · Sponsor: University of South Carolina
See eligibility & contact on ClinicalTrials.gov (NCT07471594)

A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma

Asthma Phase 3 Interventional 231 participants sought
Research Site — Columbia, South Carolina (7.9 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06023589)

A Post-Authorisation Safety Study (PASS) of Patients Treated With Lonapegsomatropin

Growth Hormone Deficiency N/A Observational 500 participants sought
Ascendis Investigational Site — Columbia, South Carolina (7.9 mi) · Sponsor: Ascendis Pharma Endocrinology Division A/S
See eligibility & contact on ClinicalTrials.gov (NCT05775523)

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Ganglioneuroblastoma, Nodular, Neuroblastoma Phase 3 Interventional 478 participants sought
Prisma Health Richland Hospital — Columbia, South Carolina (7.9 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06172296)

A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo

NonSegmental Vitiligo Phase 3 Interventional 180 participants sought
Columbia Dermatology — Columbia, South Carolina (7.9 mi) · Sponsor: Incyte Corporation
See eligibility & contact on ClinicalTrials.gov (NCT06548360)

Evaluating the Effects of Tasimelteon vs. Placebo in Delayed Sleep-Wake Phase Disorder (DSWPD)

Sleep Wake Disorders, Sleep Disorders, Circadian Rhythm Phase 3 Interventional 70 participants sought
Vanda Investigational Site — Columbia, South Carolina (7.9 mi) · Sponsor: Vanda Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT04652882)

A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma

Asthma Phase 3 Interventional 724 participants sought
Teva Investigational Site 12067 — Columbia, South Carolina (7.9 mi) · Sponsor: Teva Branded Pharmaceutical Products R&D LLC
See eligibility & contact on ClinicalTrials.gov (NCT06664619)

A US Non-interventional, Effectiveness and Safety Study of Patients Treated With SKYTROFA

Growth Hormone Deficiency N/A Observational 900 participants sought
Ascendis Investigational Site — Columbia, South Carolina (7.9 mi) · Sponsor: Ascendis Pharma Endocrinology Division A/S
See eligibility & contact on ClinicalTrials.gov (NCT05820672)

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

Metastatic Malignant Neoplasm in the Lung, Metastatic Osteosarcoma Phase 3 Interventional 62 participants sought
Prisma Health Richland Hospital — Columbia, South Carolina (7.9 mi) · Sponsor: Children's Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT05235165)

Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

Recurrent B Acute Lymphoblastic Leukemia, Recurrent B Lymphoblastic Lymphoma Phase 2 Interventional 80 participants sought
Prisma Health Richland Hospital — Columbia, South Carolina (7.9 mi) · Sponsor: Children's Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT02981628)

A Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE)

Overactive Bladder, Urge Incontinence N/A Interventional 200 participants sought
Southern Urogynecology — West Columbia, South Carolina (10.2 mi) · Sponsor: Valencia Technologies Corporation
See eligibility & contact on ClinicalTrials.gov (NCT05685433)

Electrical DN as an Adjunct to Eccentric Exercise, Stretching + MT for Achilles Tendinopathy

Achilles Tendinopathy N/A Interventional 110 participants sought
Prisma Health - Research PT Specialists — Columbia, South Carolina (7.9 mi) · Sponsor: Alabama Physical Therapy & Acupuncture
See eligibility & contact on ClinicalTrials.gov (NCT03968614)

Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

Carcinoma, Hepatocellular, Cirrhosis N/A Interventional 4,700 participants sought
Wm. Jennings Bryan Dorn VA Medical Center, Columbia, SC — Columbia, South Carolina (7.9 mi) · Sponsor: VA Office of Research and Development
See eligibility & contact on ClinicalTrials.gov (NCT05486572)

Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)

Coronary Artery Disease, High Risk Percutaneous Coronary Intervention N/A Interventional 358 participants sought
Prisma Health — Columbia, South Carolina (7.9 mi) · Sponsor: Supira Medical
See eligibility & contact on ClinicalTrials.gov (NCT07296744)

Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis (IPF) Phase 2 Interventional 40 participants sought
Bogan Sleep Consultants, LLC — Columbia, South Carolina (7.9 mi) · Sponsor: InSilico Medicine Hong Kong Limited
See eligibility & contact on ClinicalTrials.gov (NCT05975983)

Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

Breast Cancer, Cognitive Impairments N/A Interventional 386 participants sought
Lexington Medical Center — West Columbia, South Carolina (10.2 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05896189)
Google-rated

Top-rated research centers in Columbia

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Velocity Clinical Research

★ 4.0
1655 Bernardin Ave Ste 300, Columbia, SC 29204
(803) 766-2680
"Be sure to get a copy of your contract for study with payment details and a contact number for any medical complications."
— Azilee Billy, 3★

MUSC Research Center - Columbia

2001 Laurel St, Columbia, SC 29204
(803) 255-2927

Biocentric Health Research Center

★ 4.1
160 Medical Cir, West Columbia, SC 29169
(803) 764-2406
"It has been a great experience to work with this company's excellent team. They are very friendly, provide excellent service, and accommodate appoint…"
— Laura C. Bonilla, 5★

Vista Clinical Research

★ 5.0
700 Gervais St Ste 300, Columbia, SC 29201
(803) 251-1160
"ANY CALL BACK NUMBERS>>? Sleep to Heart rate and blood testing sugar testing have eating pyramids .<br>Would like to be paid for Clinical Research"
— jessie parsley, 5★

Carolina Clinical Research Services

712 Richland St # H, Columbia, SC 29201
(803) 988-0080

Columbia Digestive Health Research

2739 Laurel St Ste 2-A, Columbia, SC 29204
(803) 386-8933

South Carolina Clinical Research

1301 Taylor St #5L, Columbia, SC 29201
(803) 988-1438

USC COBRE Center for Targeted Therapeutics (CTT)

Coker Life Sciences Building, 700 Sumter St, Columbia, SC 29208
(803) 777-4689

Lexington Medical Center Park 3

★ 5.0
222 E Medical Ln, West Columbia, SC 29169
"Excellent hospital with great quality doctor and nursing care. The staff is always so very helpful and the facility is very clean."
— Denise Perez, 5★

Clinical trials in Columbia: what's recruiting

The Columbia area currently has 201 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Columbia, the most active research areas are:

  • Cancer & Oncology6 studies
  • Heart & Vascular5 studies
  • Lungs & Breathing3 studies
  • Liver & Kidney2 studies
  • Diabetes & Metabolism1 studies

Every listing shows the study phase, the recruiting site and its distance from Columbia, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Columbia

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Columbia participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Columbia?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Are clinical trials in Columbia safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Columbia, SC?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Columbia typically complete one or two studies per year.

Paid clinical trials near Columbia

Other metros within reach

Rock Hill, SC587 Charlotte, NC648 Gastonia, NC650 Augusta, GA184 Spartanburg, SC367 Concord, NC630 Charleston, SC734 Mauldin, SC382

More of SC

Charleston734 Rock Hill587 Greenville382 Mauldin382 Spartanburg367 Myrtle Beach86

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