Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/FL/Spring Hill
Updated September 2026 from ClinicalTrials.gov

Paid Clinical Trials in Spring Hill, FL

Studies commonly pay $75 to $4,500 per completed study

109 clinical trials are currently recruiting participants within 30 miles of Spring Hill. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

109studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Spring Hill right now

Top 25 of 109 recruiting studies, sorted by proximity — each links to its official registry page

Symptoms and Functions in Patients With COPD and Chronic Bronchitis Switching From CIG to THS

COPD, Smoking N/A Interventional 290 participants sought
Advanced Research Institute, Inc — New Port Richey, Florida (19.9 mi) · Sponsor: Philip Morris Products S.A.
See eligibility & contact on ClinicalTrials.gov (NCT07108166)

A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis

Colitis, Ulcerative Phase 3 Interventional 882 participants sought
Nature Coast Clinical Research — Inverness, Florida (27.4 mi) · Sponsor: Janssen Research & Development, LLC
See eligibility & contact on ClinicalTrials.gov (NCT07196748)

A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis

Uterine Fibroids, Endometriosis Phase 3 Interventional 1,000 participants sought
New Port Richey — New Port Richey, Florida (19.9 mi) · Sponsor: Sumitomo Pharma Switzerland GmbH
See eligibility & contact on ClinicalTrials.gov (NCT05862272)

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8 Phase 3 Interventional 1,209 participants sought
Moffitt Cancer Center at Wesley Chapel — Wesley Chapel, Florida (20.6 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05946213)

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

Heart Failure, Acute Heart Failure Phase 3 Interventional 5,200 participants sought
Brooksville, FL Investigative Site 10077 — Brooksville, Florida (10.0 mi) · Sponsor: Colorado Prevention Center
See eligibility & contact on ClinicalTrials.gov (NCT06008197)

Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)

Pulmonary Disease, Chronic Obstructive Phase 3 Interventional 960 participants sought
GSK Investigational Site — Brooksville, Florida (10.0 mi) · Sponsor: GlaxoSmithKline
See eligibility & contact on ClinicalTrials.gov (NCT06961214)

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

NASH - Nonalcoholic Steatohepatitis, MASH - Metabolic Dysfunction-Associated Steatohepatitis Phase 3 Interventional 2,150 participants sought
Akero Clinical Study Site — New Port Richey, Florida (19.9 mi) · Sponsor: Akero Therapeutics, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06528314)

A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

Metabolic Dysfunction-Associated Steatotic Liver Disease Phase 3 Interventional 4,500 participants sought
Nature Coast Clinical Research - Inverness — Inverness, Florida (27.4 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07165028)

A Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa Injection in Participants With Known or Suspected F2- or F3-stage MASH

Non-alcoholic Fatty Liver Disease Phase 3 Interventional 1,250 participants sought
GSK Investigational Site — Inverness, Florida (27.4 mi) · Sponsor: GlaxoSmithKline
See eligibility & contact on ClinicalTrials.gov (NCT07221188)

A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes

Type 1 Diabetes Mellitus With Hypoglycemia Phase 2 Interventional 186 participants sought
Suncoast Clinical Research — New Port Richey, Florida (19.9 mi) · Sponsor: Zucara Therapeutics Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05762107)

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

Multiple conditions Phase 2 Interventional 98 participants sought
Moffitt Cancer Center at Wesley Chapel — Wesley Chapel, Florida (20.6 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06532279)

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis Phase 3 Interventional 762 participants sought
89bio Clinical Study Site — New Port Richey, Florida (19.9 mi) · Sponsor: 89bio, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06419374)

Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

Locally Advanced Lung Non-Small Cell Carcinoma, Metastatic Lung Non-Small Cell Carcinoma Phase 1, Phase 2 Interventional 37 participants sought
Moffitt Cancer Center at Wesley Chapel — Wesley Chapel, Florida (20.6 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT07012031)

A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias

Cardiovascular, Metabolic Disease Phase 1 Interventional 90 participants sought
Research Site 19 — High Point, Florida (4.6 mi) · Sponsor: CRISPR Therapeutics AG
See eligibility & contact on ClinicalTrials.gov (NCT07491172)

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

Lymphoma, Non-Hodgkin, Multiple Myeloma Phase 2 Interventional 4,200 participants sought
Florida Cancer Specialists North / Sarah Cannon Research Institute — Trinity, Florida (22.6 mi) · Sponsor: American Society of Clinical Oncology
See eligibility & contact on ClinicalTrials.gov (NCT02693535)

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

Moderately to Severely Active Crohns Disease Phase 3 Interventional 600 participants sought
Access Research Institute — Brooksville, Florida (10.0 mi) · Sponsor: Hoffmann-La Roche
See eligibility & contact on ClinicalTrials.gov (NCT06819878)

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma Phase 3 Interventional 269 participants sought
Moffitt Cancer Center at Wesley Chapel — Wesley Chapel, Florida (20.6 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06500455)

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

Locally Advanced Cervical Adenocarcinoma, Locally Advanced Cervical Adenosquamous Carcinoma Phase 3 Interventional 336 participants sought
Moffitt Cancer Center at Wesley Chapel — Wesley Chapel, Florida (20.6 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT07061977)

eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation

Pulmonary Disease, Chronic Obstructive Phase 3 Interventional 1,196 participants sought
GSK Investigational Site — Crystal River, Florida (29.5 mi) · Sponsor: GlaxoSmithKline
See eligibility & contact on ClinicalTrials.gov (NCT07177339)

A Study to Investigate Abdominal Symptoms With Camlipixant Compared With Placebo in Adults With Irritable Bowel Syndrome - Diarrhea (IBS-D) and Irritable Bowel Syndrome - Mixed (IBS-M)

Irritable Bowel Syndrome Phase 2 Interventional 420 participants sought
GSK Investigational Site — New Port Richey, Florida (19.9 mi) · Sponsor: GlaxoSmithKline
See eligibility & contact on ClinicalTrials.gov (NCT07519395)

Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

Classic Follicular Lymphoma, Follicular Lymphoma With Unusual Cytological Features Phase 3 Interventional 600 participants sought
Moffitt Cancer Center at Wesley Chapel — Wesley Chapel, Florida (20.6 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06337318)

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

Intestinal Neoplasms, Gastrointestinal Neoplasms Phase 3 Interventional 800 participants sought
Comprehensive Hematology Oncology — Trinity, Florida (22.6 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT07222800)
Actively enrolling

Studies you may be able to join near Spring Hill

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Spring Hill

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Access Research Institute

★ 4.7
11373 Cortez Blvd Bldg C, Suite 200, Brooksville, FL 34613
(352) 691-1140
"Monika, Marilyn and shirin make my visits Easy enjoyable there was a point when I was about to quit and Monika and Marilyn spoke to me with kindness …"
— Peter Battista, 5★

Florida Cancer Specialists & Research Institute

★ 4.8 (393 reviews)
11063 County Line Rd, Spring Hill, FL 34609
(352) 688-7744
"PATRICIA lab technician she’s always smiling and hiding how rude she is she’s not professional"
— GENEISY CARTAYA VASALLO, 1★

Advanced Research Institute, Inc.

★ 5.0
7114 Congress St, New Port Richey, FL 34653
(727) 835-3261
"⭐️⭐️⭐️⭐️⭐️I was part of a clinical trial with ARI Clinical Research Florida for a little over two years, going in monthly — and I can honestly s…"
— Kimberly Hayward-Knapp, 5★

Clinical Research of West Florida, Inc - Tampa

★ 4.7
605 N Howard Ave, Tampa, FL 33606
(813) 870-1292
"Clinical research of West Florida is a great place the staff is friendly the nurses they all are great the doctor is very good I enjoyed being there …"
— Kelly Musgrave, 5★

Florida Cancer Specialists & Research Institute

★ 4.9 (723 reviews)
7154 Medical Center Dr, Spring Hill, FL 34608
(352) 596-1926

CenExel Tampa FL

★ 4.1
15416 N Florida Ave, Tampa, FL 33613
(813) 264-2155
"I am extremely disappointed with my experience and feel that I am being unfairly penalized for a mistake that was not my fault.<br><br>I participated…"
— D Hiddle, 1★

Suncoast Clinical Research

★ 5.0
5604 Gulf Dr, New Port Richey, FL 34652
(727) 849-4131
"Everyone was so friendly and professional. I felt well cared for and appreciated being part of something that helps advance medical research."
— Jana Waterworth, 5★

Florida Cancer Specialists & Research Institute

★ 4.6 (110 reviews)
14529 Cortez Blvd, Brooksville, FL 34613
(352) 596-1401
"I love Dr Malhotra,Dr Tang,Dr Li,"
— Michele Ricci, 5★

Clinical Research of West Florida , Inc - Clearwater

★ 4.9
2147 NE Coachman Rd, Clearwater, FL 33765
(727) 466-0078
"I have done several studies with this company and they are simply amazing. Every single person that works there genuinely cares about you. They are p…"
— Barbara Burns, 5★

Clinical trials in Spring Hill: what's recruiting

The Spring Hill area currently has 109 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Spring Hill, the most active research areas are:

  • Cancer & Oncology7 studies
  • Lungs & Breathing5 studies
  • Diabetes & Metabolism5 studies
  • Liver & Kidney5 studies
  • Immune & Skin2 studies

Every listing shows the study phase, the recruiting site and its distance from Spring Hill, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Spring Hill

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Spring Hill participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Spring Hill?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
How do I join a study in Spring Hill, FL?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
What is the difference between a research center and a hospital study in Spring Hill?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Spring Hill?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Spring Hill.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Spring Hill typically complete one or two studies per year.

Paid clinical trials near Spring Hill

Other metros within reach

Tampa, FL1,339 Leesburg, FL145 St. Petersburg, FL1,359 Lakeland, FL193 Ocala, FL134 Winter Haven, FL162 Kissimmee, FL925 Orlando, FL941

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Spring Hill Bladder Issues Due To Spinal Cord Injury in Spring Hill All conditions

More of FL

Fort Lauderdale1,991 Pembroke Pines1,984 Hollywood1,984 Hialeah1,940 Miami1,915 St. Petersburg1,359 Tampa1,339 Deltona953 Orlando941 Kissimmee925 Jacksonville921 Gainesville532

New paid studies open every week

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