Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/FL/Leesburg
Updated July 2026 from ClinicalTrials.gov

Paid Clinical Trials in Leesburg, FL

Studies commonly pay $75 to $4,500 per completed study

135 clinical trials are currently recruiting participants within 30 miles of Leesburg. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

135studies recruiting
9+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near Leesburg right now

Top 25 of 135 recruiting studies, sorted by proximity — each links to its official registry page

A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes

Diabetes Mellitus, Type 2 Phase 2 Interventional 270 participants sought
West Orange Endocrinology — Ocoee, Florida (25.4 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07415954)

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis, Ulcerative Colitis Chronic Phase 2 Interventional 140 participants sought
Novum Research, LLC — Clermont, Florida (16.8 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT06598943)

A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated

Diabetic Macular Edema Phase 1, Phase 2 Interventional 49 participants sought
Florida Retina Institute Wildwood — Wildwood, Florida (11.1 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT07553429)

A Clinical Study of MK-1084 With Other Treatments for Non-small Cell Lung Cancer (MK-3475-01F)

Lung Neoplasm Malignant Phase 1, Phase 2 Interventional 190 participants sought
Clermont Oncology Center ( Site 0041) — Clermont, Florida (16.8 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT07286149)

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

Non-small Cell Lung Cancer Phase 2, Phase 3 Interventional 1,260 participants sought
Clermont Oncology Center — Clermont, Florida (16.8 mi) · Sponsor: BioNTech SE
See eligibility & contact on ClinicalTrials.gov (NCT06712316)

Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids

Asthma Phase 2 Interventional 540 participants sought
Research Site — Leesburg, Florida (3.2 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06932263)

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)

Psychosis Associated With Alzheimer's Disease Phase 3 Interventional 410 participants sought
Local Institution - 1040 — The Villages, Florida (12.2 mi) · Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company
See eligibility & contact on ClinicalTrials.gov (NCT05511363)

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

Stage I Breast Cancer Phase 3 Interventional 1,670 participants sought
Health Central — Ocoee, Florida (25.4 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04852887)

A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH

Non-alcoholic Fatty Liver Disease Phase 3 Interventional 1,200 participants sought
GSK Investigational Site — Inverness, Florida (26.7 mi) · Sponsor: GlaxoSmithKline
See eligibility & contact on ClinicalTrials.gov (NCT07221227)

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

NASH With Fibrosis, MASH With Fibrosis Phase 3 Interventional 1,650 participants sought
Akero Clinical Study Site — Lady Lake, Florida (10.5 mi) · Sponsor: Akero Therapeutics, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06215716)

Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne

Acne Phase 1, Phase 2 Interventional 800 participants sought
K2 Medical Research - The Villages - Northeast 138th Lane- Site Number : 8400063 — Lady Lake, Florida (10.5 mi) · Sponsor: Sanofi Pasteur, a Sanofi Company
See eligibility & contact on ClinicalTrials.gov (NCT06316297)

A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

Obesity, Overweight Phase 3 Interventional 1,980 participants sought
Adult Medicine of Lake County, Inc. — Mt. Dora, Florida (15.4 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07321886)

Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

Psychosis Associated With Alzheimer's Disease Phase 3 Interventional 1,000 participants sought
Local Institution - 1040 — The Villages, Florida (12.2 mi) · Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company
See eligibility & contact on ClinicalTrials.gov (NCT05980949)

A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain

Osteoarthritis, Knee, Diabetic Neuropathic Pain Phase 2 Interventional 10,000 participants sought
K2 MEDICAL Research THE VILLAGES — Lady Lake, Florida (10.5 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT05986292)

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

Breast Neoplasms, Neoplasm Metastasis Phase 3 Interventional 920 participants sought
Clermont Oncology Center — Clermont, Florida (16.8 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07174336)

A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).

Alzheimer Disease, Dementia Phase 3 Interventional 550 participants sought
Charter Research - The Villages — The Villages, Florida (12.2 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07602582)

A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults

Chronic Idiopathic Constipation (CIC) Phase 3 Interventional 692 participants sought
Sensible Healthcare, LLC — Ocoee, Florida (25.4 mi) · Sponsor: Ardelyx
See eligibility & contact on ClinicalTrials.gov (NCT07382167)

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

Chronic Obstructive Pulmonary Disease (COPD) Phase 3 Interventional 990 participants sought
Research Site — Leesburg, Florida (3.2 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06878261)

A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

Early Alzheimer's Disease Phase 2 Interventional 340 participants sought
Charter Research - Lady Lake ( Site 1019) — The Villages, Florida (12.2 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT07033494)

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

Alzheimer's Disease Phase 3 Interventional 586 participants sought
Charter Research - Lady Lake — The Villages, Florida (12.2 mi) · Sponsor: Bristol-Myers Squibb
See eligibility & contact on ClinicalTrials.gov (NCT06976216)
Google-rated

Top-rated research centers in Leesburg

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Flourish Research - Leesburg

★ 5.0
1038 W N Blvd Ste 101, Leesburg, FL 34748
(352) 354-4466

Lakeview Institute of Clinical Research LLC

★ 4.0
410 Fern Dr Research, Leesburg, FL 34748
(352) 782-0606

Synexus Clinical Research Center

★ 3.7
3201 Wedgewood Ln #7179, The Villages, FL 32162
(352) 261-0901
"I had a very positive experience with Synexus Clinical Research in The Villages. The staff was professional, kind, and very helpful throughout the en…"
— Joe Martin, 5★

Orlando Clinical Research Center

★ 4.6
5055 S Orange Ave, Orlando, FL 32809
(407) 240-7878
"Friendly informative doctors and nurses..."
— Jeffrey Kallas, 5★

Charter Research

★ 4.9
1025 Lake Sumter Landing, The Villages, FL 32162
(352) 441-2000
"With appointment, no waiting. Thorough testing for your info only, and for research qualifications. No diagnosis given. Parking nearby"
— Betty Scanlon, 5★

UF Health — Precision Health Research Center

★ 4.5
1400 U.S. 27/441 Suite 820, The Villages, FL 32159
(352) 247-2493
"The dining room and food service at UF Villages is exceptional. Every visit has been a culinary delight. I love the choices available at the various…"
— Nora Cloud, 5★

Florida Cancer Specialists & Research Institute

★ 4.8 (290 reviews)
601 E Dixie Ave Ste 1001, Leesburg, FL 34748
(352) 787-9448
"I highly recommend Dr.Teklie. However, at least for this location in Leesburg, I do not recommend. Trying to get imaging approved through insurance i…"
— Brittany Nadwodny, 1★

Clinical Research AMLC

3587 Lake Center Dr, Mt Dora, FL 32757
(352) 374-0022

K2 Medical Research - The Villages, FL

★ 4.6
1400 US-441 Ste 537, The Villages, FL 32159
(352) 500-5252
"5-Stars! Professional, caring, serious about their work but they maintain a casual, friendly atmosphere. A fine medical facility and staff."
— Eric Ruff, 5★

Clinical trials in Leesburg: what's recruiting

The Leesburg area currently has 135 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Leesburg, the most active research areas are:

  • Cancer & Oncology5 studies
  • Brain & Mental Health5 studies
  • Diabetes & Metabolism4 studies
  • Immune & Skin2 studies
  • Lungs & Breathing2 studies

Every listing shows the study phase, the recruiting site and its distance from Leesburg, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Leesburg

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Leesburg participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Leesburg pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Do I need to be sick to join a clinical trial in Leesburg?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Are clinical trials in Leesburg safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How often do new paid studies open in Leesburg?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Leesburg.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Leesburg typically complete one or two studies per year.

Paid clinical trials near Leesburg

Other metros within reach

Ocala, FL124 Orlando, FL934 Kissimmee, FL920 Spring Hill, FL116 Deltona, FL948 Lakeland, FL181 Winter Haven, FL155 Tampa, FL1,310

More of FL

Fort Lauderdale1,989 Pembroke Pines1,985 Hollywood1,985 Hialeah1,939 Miami1,914 St. Petersburg1,328 Tampa1,310 Deltona948 Orlando934 Kissimmee920 Jacksonville893 Gainesville539

New paid studies open every week

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