Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
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Updated July 2026 from ClinicalTrials.gov

Paid Clinical Trials in Rancho Cucamonga, CA

Studies commonly pay $75 to $4,500 per completed study

1,457 clinical trials are currently recruiting participants within 30 miles of Rancho Cucamonga. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

1,457studies recruiting
9+research centers nearby
4condition categories
Live from the NIH registry

Studies recruiting near Rancho Cucamonga right now

Top 25 of 1,457 recruiting studies, sorted by proximity — each links to its official registry page

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
City of Hope National Medical Center — Duarte, California (23.5 mi) · Sponsor: Relay Therapeutics, Inc.

A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies

Lymphoma, B-Cell, Lymphoma, Non-Hodgkin (NHL) Phase 1 Interventional 106 participants sought
City of Hope — Duarte, California (23.5 mi) · Sponsor: Umoja Biopharma

A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)

Renal Cell Carcinoma Phase 3 Interventional 904 participants sought
Providence Medical Foundation ( Site 0141) — Fullerton, California (27.0 mi) · Sponsor: Merck Sharp & Dohme LLC

A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies

Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL) Phase 1 Interventional 248 participants sought
City of Hope — Duarte, California (23.5 mi) · Sponsor: Nurix Therapeutics, Inc.

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

Metastatic Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma Phase 3 Interventional 1,524 participants sought
UC Irvine Health/Chao Family Comprehensive Cancer Center — Orange, California (28.5 mi) · Sponsor: Alliance for Clinical Trials in Oncology

BAFFR-targeting CAR T Cells for Patients With Relapsed or Refractory B-NHL

Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma Phase 1 Interventional 36 participants sought
City of Hope Medical Center — Duarte, California (23.5 mi) · Sponsor: PeproMene Bio, Inc.

A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy

Geographic Atrophy, Macular Degeneration N/A Observational 500 participants sought
Retina Consultants of Southern CA — Redlands, California (22.5 mi) · Sponsor: Astellas Pharma Global Development, Inc.

Adjuvant Sacituzumab Govitecan and Nivolumab in Muscle-Invasive Urothelial Carcinoma at High-Risk Recurrence

Urothelial Carcinoma, Muscle-invasive Bladder Cancer Phase 2 Interventional 23 participants sought
Chao Family Comprehensive Cancer Center, University of California, Irvine — Orange, California (28.5 mi) · Sponsor: University of California, Irvine

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

Carcinoma, Non-Small Cell Lung, Squamous Cell Carcinoma of Head and Neck Phase 1 Interventional 1,006 participants sought
Providence Medical Foundation — Fullerton, California (27.0 mi) · Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Recurrent Head and Neck Squamous Cell Carcinoma, Recurrent Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 188 participants sought
Kaiser Permanente-Ontario — Ontario, California (6.4 mi) · Sponsor: National Cancer Institute (NCI)

Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia

B-cell Acute Lymphoblastic Leukemia (B-ALL) Phase 1, Phase 2 Interventional 83 participants sought
Research Site — Duarte, California (23.5 mi) · Sponsor: AstraZeneca

Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Who Are Not Achieving Glycemic Targets

Type 2 Diabetes Phase 2 Interventional 60 participants sought
Catalina Research Institute, LLC — Montclair, California (7.8 mi) · Sponsor: Biomea Fusion Inc.

Comparison of Uncomplicated Candidemia Therapy Duration in Children

Invasive Candidiasis N/A Interventional 420 participants sought
Children's Hospital of Orange County — Orange, California (28.5 mi) · Sponsor: Arkansas Children's Hospital Research Institute

PhI Pilot Study Pafolacianine Inject for Intraoperative Imaging on Outcomes of GI Cancer Peritoneal Carcinomatosis

Gastrointestinal Cancer, Peritoneal Carcinomatosis EARLY/Phase 1 Interventional 10 participants sought
Chao Family Comprehensive Cancer Center, University of California, Irvine — Orange, California (28.5 mi) · Sponsor: University of California, Irvine

Wound Irrigation With Saline Versus Hypodilute-chlorhexidine After Cesarean Section (WISHES Study)

Cesarean Section Complications, Cesarean Section; Infection N/A Interventional 400 participants sought
Loma Linda University — Loma Linda, California (18.3 mi) · Sponsor: Loma Linda University

Vedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation After Reduced Intensity Conditioning

Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia Phase 2 Interventional 35 participants sought
City of Hope Medical Center — Duarte, California (23.5 mi) · Sponsor: City of Hope Medical Center

Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors

Solid Tumor, Advanced Cancer Phase 1 Interventional 330 participants sought
Stern Center for Cancer Clinical Trials and Research — Orange, California (28.5 mi) · Sponsor: I-Mab Biopharma US Limited

ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer

Metastatic Castration-Resistant Prostate Cancer Phase 2 Interventional 200 participants sought
Innovative Clinical Research Institute — Whittier, California (28.5 mi) · Sponsor: Zenith Epigenetics

Efficacy of Preoperative Administration of Gabapentin in 3rd Molar Dental Extraction.

Dental Pain and Sensation Disorder, Pain, Postoperative Phase 4 Interventional 98 participants sought
Loma Linda University Health — Loma Linda, California (18.3 mi) · Sponsor: Loma Linda University

Evaluation of DNA Methylation Signatures for the Diagnosis and Management of Thyroid Nodules

Thyroid Gland Carcinoma N/A Interventional 1,450 participants sought
City of Hope Medical Center — Duarte, California (23.5 mi) · Sponsor: City of Hope Medical Center

A Study of REC-1245 in Participants With Unresectable, Locally Advanced, or Metastatic Cancer

Unresectable, Locally Advanced Phase 1, Phase 2 Interventional 170 participants sought
City of Hope — Duarte, California (23.5 mi) · Sponsor: Recursion Pharmaceuticals Inc.
Google-rated

Top-rated research centers in Rancho Cucamonga

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Critical Care Research Inc

★ 5.0
10743 Civic Center Dr, Rancho Cucamonga, CA 91730
(909) 987-3883
"Now look at my problem<br>Hello I am interested in attending the Friday May 29 @ 1pm information session @ University of South Alabama. My Bachelor o…"
— Kel Moy, 5★

Prospective Research Innovations Inc.

★ 5.0
8577 Haven Ave Suite 301, 8577 Haven Ave #301, Rancho Cucamonga, CA 91730
(626) 559-2770
"I've had an amazing experience with Prospective Research. The staff were really nice and caring, and the facilities were top-notch. Everything was re…"
— Ajwa Khalil, 5★

Catalina Research Institute

★ 4.5
9525 Monte Vista Ave Ste 200, Montclair, CA 91763
(909) 590-8409
"Hi my name is Lionel Thomas I value innovation, data, and helping people, participating in a clinical trial with Catalina Research Institute has been…"
— Lionel Thomas, 5★

Empire Clinical Research

★ 4.2 (39 reviews)
2740 N Garey Ave #203, Pomona, CA 91767
(909) 981-5321
"Absolutely awful.. the staff is very good, kind, but they waste your time and do not pay"
— Jeffrey Marquez, 1★

Dream Team Clinical Research

★ 5.0
1800 N Orange Grove Ave, Pomona, CA 91767
(714) 780-0076

WesternU Health Center for Clinical & Translational Research

★ 5.0
795 E 2nd St Second Floor, Suite 2003, Pomona, CA 91766
(909) 469-8626

Pacific Clinical Research

★ 1.0
1317 W Foothill Blvd, Upland, CA 91786
(909) 920-3000
"I used to come here many years ago and they helped me so much with my depression. Back then, they had so many wonderful people that were professional…"
— Kelly Ayers, 1★

National Institute of Clinical Research - Pomona

★ 5.0
630 N Park Ave, Pomona, CA 91768
(909) 766-8042
"Awesome clinical trial office the staff are incredible courteous and professional lots of trials to participate in or be on the list. All in all tops…"
— James Marquez, 5★

CenExel Riverside CA

★ 4.7
5700 Division St, Riverside, CA 92506
(866) 478-8391
"You have to experience it for yourself.."
— Jarad Racine, 5★

Clinical trials in Rancho Cucamonga: what's recruiting

The Rancho Cucamonga area currently has 1,457 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Rancho Cucamonga, the most active research areas are:

  • Cancer & Oncology17 studies
  • Liver & Kidney2 studies
  • Heart & Vascular1 studies
  • Diabetes & Metabolism1 studies

Every listing shows the study phase, the recruiting site and its distance from Rancho Cucamonga, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Rancho Cucamonga

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Rancho Cucamonga participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Are clinical trials in Rancho Cucamonga safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Rancho Cucamonga, CA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
What is the difference between a research center and a hospital study in Rancho Cucamonga?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Rancho Cucamonga?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Rancho Cucamonga.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Rancho Cucamonga typically complete one or two studies per year.

Paid clinical trials near Rancho Cucamonga

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