Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/CA/Ontario
Updated September 2026 from ClinicalTrials.gov

Paid Clinical Trials in Ontario, CA

Studies commonly pay $75 to $4,500 per completed study

1,734 clinical trials are currently recruiting participants within 30 miles of Ontario. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

1,734studies recruiting
9+research centers nearby
3condition categories
Live from the NIH registry

Studies recruiting near Ontario right now

Top 25 of 1,734 recruiting studies, sorted by proximity — each links to its official registry page

Chemoimmunotherapy and Allogeneic Stem Cell Transplant for NK T-cell Leukemia/Lymphoma

NK-Cell Lymphoma, NK-Cell Leukemia EARLY/Phase 1 Interventional 40 participants sought
Children's Hospital Orange County — Orange, California (22.4 mi) · Sponsor: New York Medical College
See eligibility & contact on ClinicalTrials.gov (NCT03719105)

Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma

T-cell Lymphoma, Cutaneous/Peripheral T-Cell Lymphoma Phase 1 Interventional 46 participants sought
City of Hope Medical Foundation — Duarte, California (22.3 mi) · Sponsor: SciTech Development, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04234048)

Emicizumab for Severe Von Willebrand Disease (VWD) and VWD/Hemophilia A

Von Willebrand Disease, Type 3, Concomitant VWD and Hemophilia Phase 1 Interventional 40 participants sought
The Center for Comprehensive Care and Diagnosis of Inherited Blood Disorders (CIBD) — Orange, California (22.4 mi) · Sponsor: Bleeding and Clotting Disorders Institute Peoria, Illinois
See eligibility & contact on ClinicalTrials.gov (NCT05500807)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Loma Linda University Medical Center — Loma Linda, California (19.8 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Lymphoma, Large B-Cell, Diffuse Phase 2 Interventional 594 participants sought
City of Hope Comprehensive Cancer Center ( Site 0191) — Duarte, California (22.3 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06890884)

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
City of Hope National Medical Center — Duarte, California (22.3 mi) · Sponsor: Relay Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06982521)

Wearable Device and Behavioral Support for Enhancing Arm Use After Stroke

Chronic Stroke Patients N/A Interventional 32 participants sought
University of California Irvine — Irvine, California (28.4 mi) · Sponsor: University of California, Irvine
See eligibility & contact on ClinicalTrials.gov (NCT07042152)

GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes

Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus N/A Interventional 400 participants sought
Loma Linda University Medical Center — Loma Linda, California (19.8 mi) · Sponsor: Medtronic MiniMed, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07228117)

A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated

Diabetic Macular Edema Phase 1, Phase 2 Interventional 49 participants sought
Win Retina — Arcadia, California (25.5 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT07553429)

Durvalumab With or Without Lenalidomide in Treating Patients With Relapsed or Refractory Cutaneous or Peripheral T Cell Lymphoma

Folliculotropic Mycosis Fungoides, Recurrent Cutaneous T-Cell Non-Hodgkin Lymphoma Phase 1, Phase 2 Interventional 78 participants sought
City of Hope Medical Center — Duarte, California (22.3 mi) · Sponsor: City of Hope Medical Center
See eligibility & contact on ClinicalTrials.gov (NCT03011814)

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

Neovascular Age-related Macular Degeneration Phase 4 Interventional 188 participants sought
Orange County Retina Med Group — Santa Ana, California (25.2 mi) · Sponsor: Genentech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04853251)

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma Phase 1 Interventional 694 participants sought
City of Hope National Medical Center /ID# 276272 — Duarte, California (22.3 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT05005403)

A Study to Evaluate the Safety of AB-1003 (Previously LION-101) in Subjects With Genetic Confirmation of LGMD2I/R9 (Part1)

Limb Girdle Muscular Dystrophy, Limb-Girdle Muscular Dystrophy Type 2 Phase 1, Phase 2 Interventional 10 participants sought
University of California - Irvine — Irvine, California (28.4 mi) · Sponsor: AskBio Inc
See eligibility & contact on ClinicalTrials.gov (NCT05230459)

Study of Inebilizumab in Pediatric Subjects With Neuromyelitis Optica Spectrum Disorder

Neuromyelitis Optica Spectrum Disorder Phase 2 Interventional 15 participants sought
Loma Linda University Children's Hospital - PIN — Loma Linda, California (19.8 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT05549258)

Shorter Versus Extended Course of Antibiotic Therapy for Necrotizing Soft Tissue Infections

Necrotizing Soft Tissue Infection N/A Observational 50 participants sought
University of California Irvine Medical Center — Orange, California (22.4 mi) · Sponsor: University of California, Irvine
See eligibility & contact on ClinicalTrials.gov (NCT06002607)

A First-in-human (FIH), Phase I Study of PTX-912 in Patients with Locally Advanced/Metastatic Solid Tumors

Advanced Cancer, Solid Tumor Phase 1 Interventional 26 participants sought
City of Hope National Medical Center — Duarte, California (22.3 mi) · Sponsor: Proviva Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06190886)

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer Phase 3 Interventional 600 participants sought
Research Site — Duarte, California (22.3 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT06989112)

KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)

Carcinoma, Non-Small-Cell Lung Phase 1, Phase 2 Interventional 450 participants sought
City of Hope ( Site 0014) — Duarte, California (22.3 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT04165070)

PyL in Patients With High Risk and Biochemically Recurrent Prostate Cancer

Prostate Cancer Phase 2 Interventional 184 participants sought
Hoag Memorial Hospital Presbyterian — Irvine, California (28.4 mi) · Sponsor: Hoag Memorial Hospital Presbyterian
See eligibility & contact on ClinicalTrials.gov (NCT04700332)

Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD

Age-Related Macular Degeneration, Geographic Atrophy N/A Interventional 125 participants sought
Loma Linda University — Loma Linda, California (19.8 mi) · Sponsor: VisionCare, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05438732)

First-in-human Study of 225Ac-PSMA-Trillium (BAY 3563254) in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)

Advanced Metastatic Castration-resistant Prostate Cancer, Prostate Specific Membrane Antigen (PSMA) Expression Phase 1 Interventional 198 participants sought
City of Hope - Duarte Cancer Center — Duarte, California (22.3 mi) · Sponsor: Bayer
See eligibility & contact on ClinicalTrials.gov (NCT06217822)

225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia Phase 1 Interventional 15 participants sought
City of Hope Medical Center — Duarte, California (22.3 mi) · Sponsor: City of Hope Medical Center
See eligibility & contact on ClinicalTrials.gov (NCT06287944)

Integrating CHWs Into Prenatal Care for Maternal Smoking Cessation

Tobacco Use, Tobacco Use Cessation N/A Interventional 105 participants sought
Loma Linda University Medical Center — Loma Linda, California (19.8 mi) · Sponsor: Loma Linda University
See eligibility & contact on ClinicalTrials.gov (NCT06438549)
Actively enrolling

Studies you may be able to join near Ontario

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Ontario

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Catalina Research Institute

★ 4.5
9525 Monte Vista Ave Ste 200, Montclair, CA 91763
(909) 590-8409
"Hi my name is Lionel Thomas I value innovation, data, and helping people, participating in a clinical trial with Catalina Research Institute has been…"
— Lionel Thomas, 5★

Brio Clinical

★ 3.6
1910 S Archibald Ave # U, Ontario, CA 91761
(951) 465-3500
"It seems like the staffing team doesn't really know how to properly update or communicate regarding referrals—or perhaps they just don't prioritize t…"
— Dezza Barredo-Alcala, 1★

Empire Clinical Research

★ 4.2 (39 reviews)
2740 N Garey Ave #203, Pomona, CA 91767
(909) 981-5321
"Absolutely awful.. the staff is very good, kind, but they waste your time and do not pay"
— Jeffrey Marquez, 1★

Dream Team Clinical Research

★ 5.0
1800 N Orange Grove Ave, Pomona, CA 91767
(714) 780-0076

WesternU Health Center for Clinical & Translational Research

★ 5.0
795 E 2nd St Second Floor, Suite 2003, Pomona, CA 91766
(909) 469-8626

Critical Care Research Inc

★ 5.0
10743 Civic Center Dr, Rancho Cucamonga, CA 91730
(909) 987-3883
"Now look at my problem<br>Hello I am interested in attending the Friday May 29 @ 1pm information session @ University of South Alabama. My Bachelor o…"
— Kel Moy, 5★

Prospective Research Innovations Inc.

★ 5.0
8577 Haven Ave Suite 301, 8577 Haven Ave #301, Rancho Cucamonga, CA 91730
(626) 559-2770
"I've had an amazing experience with Prospective Research. The staff were really nice and caring, and the facilities were top-notch. Everything was re…"
— Ajwa Khalil, 5★

Infinity Clinical Research

★ 3.5
1901 Town and Country Dr Ste 104, Norco, CA 92860
(714) 252-6689
"I just completed a year-long clinical research trial and had an excellent experience! The staff at the Norco location were always professional, knowl…"
— Jonnine Eras, 5★

National Institute of Clinical Research - Pomona

★ 5.0
630 N Park Ave, Pomona, CA 91768
(909) 766-8042
"Awesome clinical trial office the staff are incredible courteous and professional lots of trials to participate in or be on the list. All in all tops…"
— James Marquez, 5★

Clinical trials in Ontario: what's recruiting

The Ontario area currently has 1,734 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Ontario, the most active research areas are:

  • Cancer & Oncology14 studies
  • Heart & Vascular2 studies
  • Diabetes & Metabolism2 studies

Every listing shows the study phase, the recruiting site and its distance from Ontario, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Ontario

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Ontario participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Are clinical trials in Ontario safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Ontario, CA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
What is the difference between a research center and a hospital study in Ontario?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Ontario typically complete one or two studies per year.

Paid clinical trials near Ontario

Other metros within reach

Rancho Cucamonga, CA1,494 Pomona, CA3,156 Fontana, CA985 Corona, CA1,595 Riverside, CA960 Anaheim, CA3,199 San Bernardino, CA465 Fullerton, CA3,257

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Ontario Bladder Issues Due To Spinal Cord Injury in Ontario All conditions

More of CA

Long Beach3,373 Torrance3,260 Fullerton3,257 Anaheim3,199 Garden Grove3,191 Pomona3,156 Glendale2,966 Los Angeles2,950 Huntington Beach2,870 Santa Clarita2,384 Hayward2,256 Oakland2,247

New paid studies open every week

Get an email when a new clinical trial starts recruiting within 30 miles of your ZIP code. No spam — only real studies from the NIH registry.

By subscribing you agree to receive study alert emails. Unsubscribe anytime in one click.

Get free trial alerts