Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/CA/Santa Clarita
Updated September 2026 from ClinicalTrials.gov

Paid Clinical Trials in Santa Clarita, CA

Studies commonly pay $75 to $4,500 per completed study

2,384 clinical trials are currently recruiting participants within 30 miles of Santa Clarita. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

2,384studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Santa Clarita right now

Top 25 of 2,384 recruiting studies, sorted by proximity — each links to its official registry page

One-Time DNA Study for Vasculitis

Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss), Giant Cell Arteritis N/A Observational 1,000 participants sought
Cedars-Sinai Medical Center — Los Angeles, California (29.1 mi) · Sponsor: University of Pennsylvania
See eligibility & contact on ClinicalTrials.gov (NCT01241305)

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Kaiser Permanente - Panorama City — Panorama City, California (13.6 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma

T-cell Lymphoma, Cutaneous/Peripheral T-Cell Lymphoma Phase 1 Interventional 46 participants sought
University of Southern California — Los Angeles, California (29.1 mi) · Sponsor: SciTech Development, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04234048)

Study to Assess the Impact of the Urine Test Cxbladder Triage Plus on the Number of Cystoscopies Performed on Patients With Invisible Blood in Their Urine.

Hematuria - Cause Not Known N/A Interventional 1,000 participants sought
Urology Group of Southern California — Los Angeles, California (29.1 mi) · Sponsor: Pacific Edge Limited
See eligibility & contact on ClinicalTrials.gov (NCT06394869)

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Lymphoma, Large B-Cell, Diffuse Phase 2 Interventional 594 participants sought
Roy and Patricia Disney Family Cancer Center - Providence Saint Joseph Medical Center ( Site 0135) — Burbank, California (19.5 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06890884)

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
Beverly Hills Cancer Center — Beverly Hills, California (24.4 mi) · Sponsor: Relay Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06982521)

A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated

Diabetic Macular Edema Phase 1, Phase 2 Interventional 49 participants sought
Global Research Management — Glendale, California (23.5 mi) · Sponsor: Boehringer Ingelheim
See eligibility & contact on ClinicalTrials.gov (NCT07553429)

Post-Marketing Study for Early-Stage Low-Risk Breast Cancer Treatment Using ProSense® Cryoablation (ChoICE Trial)

Low-Risk, Early Stage Breast Cancer N/A Interventional 400 participants sought
Glendale Adventist Medical Center d/b/a Adventist Health Glendale — Glendale, California (23.5 mi) · Sponsor: IceCure Medical Ltd.
See eligibility & contact on ClinicalTrials.gov (NCT07629206)

Regional Blocks for Lateral Condyle Fractures

Fractures, Closed, Humeral Fractures Phase 4 Interventional 90 participants sought
Orthopaedic Institute for Children — Los Angeles, California (29.1 mi) · Sponsor: University of California, Los Angeles
See eligibility & contact on ClinicalTrials.gov (NCT03796572)

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

Neovascular Age-related Macular Degeneration Phase 4 Interventional 188 participants sought
California Eye Specialists Medical group Inc. — Pasadena, California (27.4 mi) · Sponsor: Genentech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04853251)

A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.

Triple Negative Breast Cancer, Diffuse Large B Cell Lymphoma Phase 1 Interventional 168 participants sought
California Research Institute — Los Angeles, California (29.1 mi) · Sponsor: OncoNano Medicine, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06022029)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
Children's Hospital Los Angeles — Los Angeles, California (29.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

Motivation for IV Alcohol Self-Administration in Humans

Alcohol Use Disorder Phase 2 Interventional 210 participants sought
University of California, Los Angeles — Los Angeles, California (29.1 mi) · Sponsor: University of California, Los Angeles
See eligibility & contact on ClinicalTrials.gov (NCT06494891)

Using Navigation to Improve Accuracy of Maxillary Balloon Sinusotomy

Chronic Maxillary Rhinosinusitis Phase 2, Phase 3 Interventional 50 participants sought
Cedars Sinai — Los Angeles, California (29.1 mi) · Sponsor: Cedars-Sinai Medical Center
See eligibility & contact on ClinicalTrials.gov (NCT06567821)

A Study to Investigate the Safety and Efficacy of MEDI0618 Compared to Placebo in Adult Participants With Episodic Migraine

Migraine Phase 2 Interventional 488 participants sought
Clinical Research Institute, LCC — Los Angeles, California (29.1 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06602479)

Towards Restoring Complex Movement After Paralysis: Algorithm Development With Healthy Participants

Movement Disorders, Neurorehabilitation N/A Interventional 50 participants sought
UCLA Neural Engineering and Computation Lab — Los Angeles, California (29.1 mi) · Sponsor: University of California, Los Angeles
See eligibility & contact on ClinicalTrials.gov (NCT07236892)

A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 1

Narcolepsy Type 1 Phase 3 Interventional 150 participants sought
Alkermes Investigational Site — Los Angeles, California (29.1 mi) · Sponsor: Alkermes, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07455383)

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma Phase 1 Interventional 694 participants sought
USC Norris Comprehensive Cancer Center /ID# 279603 — Los Angeles, California (29.1 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT05005403)

PEACE Trial: Postpartum Evaluation of Antihypertensive Cessation and Efficacy

Postpartum Hypertension (PPHT) Phase 4 Interventional 110 participants sought
UCLA Ronald Reagan — Los Angeles, California (29.1 mi) · Sponsor: University of California, Los Angeles
See eligibility & contact on ClinicalTrials.gov (NCT06915792)

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)

Ulcerative Colitis Phase 2 Interventional 224 participants sought
Gastro Care Institute — Lancaster, California (28.2 mi) · Sponsor: Genentech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06979336)

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

Solid Tumor, Non-Small-Cell Lung Cancer Phase 1 Interventional 364 participants sought
UCLA Santa Monica Hematology Oncology — Santa Monica, California (27.5 mi) · Sponsor: Astellas Pharma Inc
See eligibility & contact on ClinicalTrials.gov (NCT07094204)
Actively enrolling

Studies you may be able to join near Santa Clarita

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Santa Clarita

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Clearview Medical Research

27141 Hidaway Ave #103, Canyon Country, CA 91351
(323) 633-4730

Flourish Research - Los Angeles (Northridge)

★ 4.9
18433 Roscoe Blvd #208, Northridge, CA 91325
(818) 280-4220
"This clinic is the best and stuff are great and caring if you need to get studied go here in Northridge ."
— John Cariaga (Jon jon), 5★

Clinical Research of California

★ 4.3
7301 Medical Center Dr Unit 405, West Hills, CA 91307

Alliance Research Institute(Roscoe Blvd)

★ 3.9
22110 Roscoe Blvd Suite 202, Canoga Park, CA 91304
(818) 835-9085
"This organization is deceptive, ill trained and will waste your time without any compensation. I have done other trails, and always had a good expe…"
— Michael Nuttall, 1★

Valiance Clinical Research Northridge

★ 5.0
19355 Business Ctr Dr Ste. 2, Northridge, CA 91324
(747) 799-0050
"Went there for a Research project. Ask first about parking. Staff is very helpful and kind, especially Natalie and Justin."
— KAILEH PISTOL (UrbaneGypsy), 5★

Clinical Research Center Centro De Estudios Clinicos

Los Angeles, CA 91345

Alliance Clinical Canoga Park

★ 3.5
22030 Sherman Way #101, Canoga Park, CA 91303
(818) 999-4673
"I was called for a longterm study on migraines. My appointment was 2:30 pm. They were quite rude. She had a tizzy fit that I had a slice of toast and…"
— Paulette carr, 1★

Asclepes Research

★ 3.8
14860 Roscoe Blvd #304, Panorama City, CA 91402
(844) 283-3649
"Where we’re going to my moms appointment and the worker that was at the lobby where we had to wait so my mom can get inside and the worker was yellin…"
— Uriel Recendez, 1★

Northridge Clinical Trials

★ 4.8 (17 reviews)
18433 Roscoe Blvd Ste 101, Northridge, CA 91325
(818) 350-7482
"Loved it here, Luke was so friendly and I love having to talk to them and come here!"
— kenneth lee, 5★

Clinical trials in Santa Clarita: what's recruiting

The Santa Clarita area currently has 2,384 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Santa Clarita, the most active research areas are:

  • Cancer & Oncology11 studies
  • Heart & Vascular2 studies
  • Brain & Mental Health1 studies
  • Diabetes & Metabolism1 studies
  • Immune & Skin1 studies

Every listing shows the study phase, the recruiting site and its distance from Santa Clarita, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Santa Clarita

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Santa Clarita participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Santa Clarita pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Santa Clarita safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Santa Clarita, CA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
What is the difference between a research center and a hospital study in Santa Clarita?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Santa Clarita?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Santa Clarita.

Paid clinical trials near Santa Clarita

Other metros within reach

Los Angeles, CA2,950 Glendale, CA2,966 Lancaster, CA107 Palmdale, CA129 Thousand Oaks, CA667 Torrance, CA3,260 Long Beach, CA3,373 Oxnard, CA128

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Santa Clarita Bladder Issues Due To Spinal Cord Injury in Santa Clarita All conditions

More of CA

Long Beach3,373 Torrance3,260 Fullerton3,257 Anaheim3,199 Garden Grove3,191 Pomona3,156 Glendale2,966 Los Angeles2,950 Huntington Beach2,870 Hayward2,256 Oakland2,247

New paid studies open every week

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