Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/CA/San Francisco
Updated July 2026 from ClinicalTrials.gov

Paid Clinical Trials in San Francisco, CA

Studies commonly pay $75 to $4,500 per completed study

2,228 clinical trials are currently recruiting participants within 30 miles of San Francisco. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

2,228studies recruiting
8+research centers nearby
6condition categories
Live from the NIH registry

Studies recruiting near San Francisco right now

Top 25 of 2,228 recruiting studies, sorted by proximity — each links to its official registry page

QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 in HER2-low Metastatic Breast Cancer

HER2-positive Metastatic Breast Cancer N/A Observational 200 participants sought
University of California San Francisco Medical Center — San Francisco, California (1.9 mi) · Sponsor: Abramson Cancer Center at Penn Medicine
See eligibility & contact on ClinicalTrials.gov (NCT06551116)

The Osteoporotic Fracture Classification-based Scoring System for Treatment Decision in Thoracolumbar Osteoporotic Fractures

Osteoporotic Fractures, Osteoporosis N/A Observational 648 participants sought
University of California San Francisco (USCF) Department of Orthopaedic Surgery — San Francisco, California (1.9 mi) · Sponsor: AO Foundation, AO Spine
See eligibility & contact on ClinicalTrials.gov (NCT07027306)

Exploring Clinical Utility of Wearables for the Bladder in Pelvic Health Physical Therapy Clinics

Postpartum Bladder Dysfunction, Post-prostatectomy Bladder Dysfunction N/A Observational 25 participants sought
University of California San Francisco Weill Institute for Neurosciences — San Francisco, California (1.9 mi) · Sponsor: University of California, San Francisco
See eligibility & contact on ClinicalTrials.gov (NCT07451106)

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
University of California San Francisco (UCSF) Helen Diller Family Comprehensive Cancer Center — San Francisco, California (1.9 mi) · Sponsor: Relay Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06982521)

Natural History of Medullary Thyroid Cancer to Inform Advanced Disease Management

Advanced Thyroid Gland Medullary Carcinoma, Stage III Thyroid Gland Medullary Carcinoma AJCC v8 N/A Observational 2,030 participants sought
University of California San Francisco — San Francisco, California (1.9 mi) · Sponsor: M.D. Anderson Cancer Center
See eligibility & contact on ClinicalTrials.gov (NCT04216732)

AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss

Obesity Phase 3 Interventional 600 participants sought
Diablo Clinical Research, Inc. — Walnut Creek, California (23.2 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07503210)

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

Neovascular Age-related Macular Degeneration Phase 4 Interventional 188 participants sought
University of California San Francisco — San Francisco, California (1.9 mi) · Sponsor: Genentech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04853251)

A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies

Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL) Phase 1 Interventional 248 participants sought
University of California San Francisco Medical Center — San Francisco, California (1.9 mi) · Sponsor: Nurix Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04830137)

Abatacept for the Treatment of Common Variable Immunodeficiency With Interstitial Lung Disease

Interstitial Lung Disease, Common Variable Immunodeficiency Phase 2 Interventional 38 participants sought
University of California, San Francisco — San Francisco, California (1.9 mi) · Sponsor: Children's Hospital Medical Center, Cincinnati
See eligibility & contact on ClinicalTrials.gov (NCT04925375)

BAFFR-targeting CAR T Cells for Patients With Relapsed or Refractory B-NHL

Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma Phase 1 Interventional 36 participants sought
Stanford University — Stanford, California (27.5 mi) · Sponsor: PeproMene Bio, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05370430)

Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T Cells

EGFR Gene Mutation, Glioblastoma Phase 1 Interventional 20 participants sought
University of California, San Francisco — San Francisco, California (1.9 mi) · Sponsor: Hideho Okada, MD, PhD
See eligibility & contact on ClinicalTrials.gov (NCT06186401)

A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

Ulcerative Colitis, Crohn's Disease Phase 3 Interventional 240 participants sought
University of California San Francisco — San Francisco, California (1.9 mi) · Sponsor: Takeda
See eligibility & contact on ClinicalTrials.gov (NCT05442567)

A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

Obesity, Knee Osteoarthritis (OA) Phase 3 Interventional 400 participants sought
Diablo Clinical Research, Inc. — Walnut Creek, California (23.2 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07481630)

Mirdametinib in Patients With Advanced NF1-mutant Melanoma

Advanced Unresectable Melanoma, Metastatic Melanoma Phase 2 Interventional 10 participants sought
California Pacific Medical Center - Sutter Health — San Francisco, California (1.9 mi) · Sponsor: Kevin Kim, MD
See eligibility & contact on ClinicalTrials.gov (NCT07237100)

Simplified, Scalable, 24-hour Adaptive DBS in Parkinson's Disease

PD - Parkinson's Disease N/A Interventional 24 participants sought
University of California San Francisco — San Francisco, California (1.9 mi) · Sponsor: University of California, San Francisco
See eligibility & contact on ClinicalTrials.gov (NCT07398157)

A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes

Diabetes Mellitus, Type 2 Phase 2 Interventional 270 participants sought
Diablo Clinical Research, Inc. — Walnut Creek, California (23.2 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07415954)

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

Amyloidosis, Amyloid Cardiomyopathy Phase 3 Interventional 587 participants sought
University of California, San Francisco (UCSF) — San Francisco, California (1.9 mi) · Sponsor: Eidos Therapeutics, a BridgeBio company
See eligibility & contact on ClinicalTrials.gov (NCT06563895)

Longitudinal Early-onset Alzheimer's Disease Study Protocol

Early Onset Alzheimer Disease, Alzheimer Disease N/A Observational 850 participants sought
University of California, San Francisco — San Francisco, California (1.9 mi) · Sponsor: Indiana University
See eligibility & contact on ClinicalTrials.gov (NCT03507257)

Wearable Activity Tracking to Curb Hospitalizations

Hematopoietic Neoplasm, Malignant Solid Neoplasm N/A Observational 260 participants sought
University of California, San Francisco — San Francisco, California (1.9 mi) · Sponsor: University of California, San Francisco
See eligibility & contact on ClinicalTrials.gov (NCT06587100)
Google-rated

Top-rated research centers in San Francisco

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

California Pacific Medical Center Research Institute: Sutter Health Affiliate

★ 3.5
475 Brannan St #130, San Francisco, CA 94107
(415) 600-1600

SF Research Institute Inc.

★ 3.2
2566 Ocean Ave, San Francisco, CA 94132
(415) 745-4340

Center For Clinical Research

★ 5.0
2299 Post St Ste 210, San Francisco, CA 94115
(800) 363-1069
"These people are very friendly and experienced from top to bottom."
— Greg Rodriguez, 5★

Power Clinical Trials

461 2ND ST SAN FRANCISCO C131, San Francisco, CA 94107
(415) 900-4227

Quest Clinical Research

★ 5.0
2300 Sutter St #202, San Francisco, CA 94115
(415) 353-0800
"Quest is an amazing medical research company that has offered cutting edge investigational and trial ttherapy to thousands of patients with HIV and h…"
— Karl Eriksen, 5★

SF Infectious Diseases Research Center

2540 23rd St, San Francisco, CA 94110
(415) 806-8554

UCSF Cancer Clinical Trials and Investigational Treatments Center

1825 4th St Fifth Floor, San Francisco, CA 94158
(415) 885-7796

CPMC Research Institute

★ 5.0
2330 Clay St, San Francisco, CA 94115
(415) 561-1785

Clinical trials in San Francisco: what's recruiting

The San Francisco area currently has 2,228 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to San Francisco, the most active research areas are:

  • Cancer & Oncology7 studies
  • Diabetes & Metabolism5 studies
  • Immune & Skin3 studies
  • Heart & Vascular2 studies
  • Brain & Mental Health2 studies

Every listing shows the study phase, the recruiting site and its distance from San Francisco, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in San Francisco

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

San Francisco participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in San Francisco?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Are clinical trials in San Francisco safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in San Francisco, CA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
How often do new paid studies open in San Francisco?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of San Francisco.

Paid clinical trials near San Francisco

Other metros within reach

Oakland, CA2,249 Hayward, CA2,256 Vallejo, CA1,502 Concord, CA1,509 Fremont, CA2,245 Sunnyvale, CA1,163 Fairfield, CA349 Antioch, CA445

More of CA

Long Beach3,341 Torrance3,236 Fullerton3,223 Anaheim3,155 Garden Grove3,152 Pomona3,119 Glendale2,957 Los Angeles2,943 Huntington Beach2,841 Santa Clarita2,395 Hayward2,256 Oakland2,249

New paid studies open every week

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