Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/CA/Sacramento
Updated July 2026 from ClinicalTrials.gov

Paid Clinical Trials in Sacramento, CA

Studies commonly pay $75 to $4,500 per completed study

627 clinical trials are currently recruiting participants within 30 miles of Sacramento. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

627studies recruiting
9+research centers nearby
4condition categories
Live from the NIH registry

Studies recruiting near Sacramento right now

Top 25 of 627 recruiting studies, sorted by proximity — each links to its official registry page

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
University of California, Davis Comprehensive Cancer Center — Sacramento, California (1.7 mi) · Sponsor: Relay Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06982521)

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

Neovascular Age-related Macular Degeneration Phase 4 Interventional 188 participants sought
Retinal Consultants Med Group — Sacramento, California (1.7 mi) · Sponsor: Genentech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04853251)

Outcomes of Running Locking Suture vs Standard Running Suture in Surgical Wounds

Scarring N/A Interventional 50 participants sought
University of California, Davis - Dermatology Department — Sacramento, California (1.7 mi) · Sponsor: University of California, Davis
See eligibility & contact on ClinicalTrials.gov (NCT06288009)

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

Metastatic Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma Phase 3 Interventional 1,524 participants sought
University of California Davis Comprehensive Cancer Center — Sacramento, California (1.7 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT07200830)

Phase 2 EL219 Versus Liposomal Amphotericin B or Voriconazole for Early Antifungal Therapy

Invasive Mould Infection Phase 2 Interventional 60 participants sought
UC Davis Medical Center — Sacramento, California (1.7 mi) · Sponsor: Elion Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07215273)

Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection

Viral Pneumonia Phase 2 Interventional 550 participants sought
University of California - Davis — Sacramento, California (1.7 mi) · Sponsor: Synairgen Research Ltd.
See eligibility & contact on ClinicalTrials.gov (NCT06999603)

A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy

Geographic Atrophy, Macular Degeneration N/A Observational 500 participants sought
Retinal Consultants Medical Group Inc — Sacramento, California (1.7 mi) · Sponsor: Astellas Pharma Global Development, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06779773)

Coordinating Outpatient bupreNorphiNe for Emergency Care and Continuing Treatment

Opioid Use Disorder N/A Interventional 3,492 participants sought
University of California Davis Emergency Department — Sacramento, California (1.7 mi) · Sponsor: University of California, Davis
See eligibility & contact on ClinicalTrials.gov (NCT07024498)

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Recurrent Head and Neck Squamous Cell Carcinoma, Recurrent Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 188 participants sought
Sutter Cancer Centers Radiation Oncology Services-Roseville — Roseville, California (16.0 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04671667)

A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)

Relapsed Refractory Multiple Myeloma Phase 3 Interventional 508 participants sought
Research Site — Sacramento, California (1.7 mi) · Sponsor: AstraZeneca
See eligibility & contact on ClinicalTrials.gov (NCT07391657)

Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

Locally Advanced Lung Non-Small Cell Carcinoma, Metastatic Lung Non-Small Cell Carcinoma Phase 1, Phase 2 Interventional 37 participants sought
University of California Davis Comprehensive Cancer Center — Sacramento, California (1.7 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT07012031)

Sacramento Clinical High Risk for Psychosis Stepped-Care Program

Clinical High Risk for Psychosis, Ultra High Risk for Psychosis N/A Interventional 223 participants sought
University of California Department of Psychiatry and Behavioral Sciences; Early Psychosis Programs — Sacramento, California (1.7 mi) · Sponsor: University of California, Davis
See eligibility & contact on ClinicalTrials.gov (NCT06640803)

Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations

Non-Small-Cell Lung Cancer, Metastatic Non-Small-Cell Lung Cancer Phase 3 Interventional 480 participants sought
University of California Davis Comprehensive Cancer Center — Sacramento, California (1.7 mi) · Sponsor: ArriVent BioPharma, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07185997)

A Study to Investigate Safety and Efficacy of Tapinarof Cream, 1% in Participants Ages 3 Months to < 24 Months With Atopic Dermatitis

Atopic Dermatitis Phase 3 Interventional 180 participants sought
Integrative Skin Science and Research — Sacramento, California (1.7 mi) · Sponsor: Organon and Co
See eligibility & contact on ClinicalTrials.gov (NCT07265479)

A Post-Authorisation Safety Study (PASS) of Patients Treated With Lonapegsomatropin

Growth Hormone Deficiency N/A Observational 500 participants sought
Ascendis Investigational Site — Sacramento, California (1.7 mi) · Sponsor: Ascendis Pharma Endocrinology Division A/S
See eligibility & contact on ClinicalTrials.gov (NCT05775523)

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Ganglioneuroblastoma, Nodular, Neuroblastoma Phase 3 Interventional 478 participants sought
Sutter Medical Center Sacramento — Sacramento, California (1.7 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06172296)

Clinical Trial Exploring the Outpatient Treatment of Phantom Limb Pain With Ketamine Administration in a Six Month Study With a Minimum Remission Period of 7 Days Between Treatment Session. 25-30 Subjects With an Ongoing History of Significant PLP.--FDA and IRB Approved.

Phantom Limb Syndrome With Pain Phase 2, Phase 3 Interventional 30 participants sought
Shamynds — Sacramento, California (1.7 mi) · Sponsor: The Ketamine Research Foundation
See eligibility & contact on ClinicalTrials.gov (NCT07276542)

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

Plasma Cell Myeloma, RISS Stage I Plasma Cell Myeloma Phase 3 Interventional 1,450 participants sought
Mercy Cancer Center - Sacramento — Sacramento, California (1.7 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT04566328)

Locally ablatIVe thErapy for oLigo-progressive gastrOintestiNal maliGnancies (LIVELONG)

Small Bowel Cancer, Colorectal Cancer N/A Interventional 300 participants sought
University of California, Davis Comprehensive Cancer Center — Sacramento, California (1.7 mi) · Sponsor: University of California, Davis
See eligibility & contact on ClinicalTrials.gov (NCT06101277)

Effects of PFC tDCS on Cognitive Control, Attention Lapses and Coordinated Neural Activity in the Theta and Alpha Bands

Healthy N/A Interventional 75 participants sought
Imaging Research Center — Sacramento, California (1.7 mi) · Sponsor: University of California, Davis
See eligibility & contact on ClinicalTrials.gov (NCT04885322)

Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

Metastatic Clear Cell Renal Cell Carcinoma, Advanced Clear Cell Renal Cell Carcinoma Phase 3 Interventional 720 participants sought
Research Site — Sacramento, California (1.7 mi) · Sponsor: Arcus Biosciences, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07011719)

Safety and Efficacy of Endovascular Treatment of Intracranial Aneurysms With Surpass Elite With GUARDian Flow Diverter (GUARD)

Aneurysm, Aneurysm, Intracranial N/A Interventional 183 participants sought
University of California Davis Health — Davis, California (14.8 mi) · Sponsor: Stryker Neurovascular
See eligibility & contact on ClinicalTrials.gov (NCT06872684)
Google-rated

Top-rated research centers in Sacramento

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Sutter Institute for Medical Research: Sutter Medical Center, Sacramento

★ 4.5
2801 Capitol Ave #400, Sacramento, CA 95816
(916) 453-5898
"Nice and friendly, they called me at my appointment time. Not a lot of seating in the waiting room."
— stephen scharp, 4★

UC Davis Clinical and Translational Science Center

★ 1.8
2921 Stockton Blvd #2305, Sacramento, CA 95817
(916) 703-9184

UC Davis Health - Participate in Clinical Trials

2921 Stockton Blvd, Sacramento, CA 95817
(855) 823-1660

Integrative Research Institute

★ 5.0
4825 J St Ste 100, Sacramento, CA 95819
(916) 775-5080
"Great team of specialists. Very nice staff."
— Angelina Begas, 5★

Center for Healthcare Policy & Research

4480 2nd Ave, Sacramento, CA 95817
(916) 734-7918

UC Davis Center for Precision Medicine and Data Sciences

Education Building, 4610 X St Suite 3126, Sacramento, CA 95817

Clinical Trials Research

★ 5.0
3750 Auburn Blvd Ste A, Sacramento, CA 95821
(916) 487-8230
"I asked for a business location and it popped right up."
— Barbara McGarvey, 5★

UC Davis Cypress Bldg

★ 3.5
2221 Stockton Blvd, Sacramento, CA 95817
(916) 734-2011
"This lab is hit and miss for decent service. Some of the people who work there are rude and they are SLOW! Some are super chatty, like we don't have …"
— Ambulatory, 1★

UC Davis Health Alzheimer's Disease Research Center

1651 Alhambra Blvd #200a, Sacramento, CA 95816
(916) 734-5496

Clinical trials in Sacramento: what's recruiting

The Sacramento area currently has 627 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Sacramento, the most active research areas are:

  • Cancer & Oncology10 studies
  • Immune & Skin3 studies
  • Heart & Vascular2 studies
  • Liver & Kidney2 studies

Every listing shows the study phase, the recruiting site and its distance from Sacramento, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Sacramento

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Sacramento participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in Sacramento?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
How do I join a study in Sacramento, CA?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
What is the difference between a research center and a hospital study in Sacramento?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in Sacramento?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Sacramento.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Sacramento typically complete one or two studies per year.

Paid clinical trials near Sacramento

Other metros within reach

Elk Grove, CA620 Roseville, CA628 Stockton, CA100 Fairfield, CA349 Antioch, CA445 Concord, CA1,509 Vallejo, CA1,502 Modesto, CA99

More of CA

Long Beach3,341 Torrance3,236 Fullerton3,223 Anaheim3,155 Garden Grove3,152 Pomona3,119 Glendale2,957 Los Angeles2,943 Huntington Beach2,841 Santa Clarita2,395 Hayward2,256 Oakland2,249

New paid studies open every week

Get an email when a new clinical trial starts recruiting within 30 miles of your ZIP code. No spam — only real studies from the NIH registry.

By subscribing you agree to receive study alert emails. Unsubscribe anytime in one click.

Get free trial alerts