Are clinical trials in McAllen safe?

Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.

How do I join a study in McAllen, TX?

Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.

Is compensation for clinical trials taxable?

In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.

How often do new paid studies open in McAllen?

Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of McAllen.

Can I be in more than one clinical trial at a time?

Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in McAllen typically complete one or two studies per year.

Paid Clinical Trials McAllen, TX — 133 Studies Recruiting (Jul 2026)

A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy

Geographic Atrophy, Macular Degeneration N/A Observational 500 participants sought

Valley Retina Institute — McAllen, Texas (1.8 mi) · Sponsor: Astellas Pharma Global Development, Inc.

See eligibility & contact on ClinicalTrials.gov (NCT06779773)

Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis

Knee Cartilage Defects Phase 3 Interventional 300 participants sought

Futuro Clinical Trials — McAllen, Texas (1.8 mi) · Sponsor: Medipost, Inc.

See eligibility & contact on ClinicalTrials.gov (NCT07339111)

Efficacy of Fusidic Acid 1% in the Treatment of Bacterial Conjunctivitis

Bacterial Conjunctivitis Phase 3 Interventional 400 participants sought

Baxis Site 36 — Mission, Texas (4.9 mi) · Sponsor: Baxis Pharmaceuticals, Inc.

See eligibility & contact on ClinicalTrials.gov (NCT06911424)

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis, Ulcerative Colitis Chronic Phase 2 Interventional 140 participants sought

DHR Health Gastroenterology - Edinburg — Edinburg, Texas (7.4 mi) · Sponsor: Eli Lilly and Company

See eligibility & contact on ClinicalTrials.gov (NCT06598943)

A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)

Staphylococcus Aureus Phase 1, Phase 2 Interventional 231 participants sought

Research Site — McAllen, Texas (1.8 mi) · Sponsor: AstraZeneca

See eligibility & contact on ClinicalTrials.gov (NCT06749457)

A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia

Hyperphosphatemia, Chronic Kidney Disease Requiring Chronic Dialysis Phase 2 Interventional 168 participants sought

Gamma Medical Research — McAllen, Texas (1.8 mi) · Sponsor: R1 Therapeutics

See eligibility & contact on ClinicalTrials.gov (NCT06712654)

A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated

Diabetic Macular Edema Phase 1, Phase 2 Interventional 49 participants sought

Valley Retina Institute, PA — McAllen, Texas (1.8 mi) · Sponsor: Boehringer Ingelheim

See eligibility & contact on ClinicalTrials.gov (NCT07553429)

Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)

Neovascular Age-Related Macular Degeneration (nAMD), Wet AMD Phase 3 Interventional 284 participants sought

Adverum Clinical Site 162 — McAllen, Texas (1.8 mi) · Sponsor: Adverum Biotechnologies, Inc.

See eligibility & contact on ClinicalTrials.gov (NCT07482176)

Lot-to-lot Consistency Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From 2 Months of Age

Pneumococcal Immunization, Healthy Volunteers Phase 3 Interventional 2,195 participants sought

PAS Research - Children's Care Clinic- Site Number : 8400035 — Edinburg, Texas (7.4 mi) · Sponsor: Sanofi

See eligibility & contact on ClinicalTrials.gov (NCT07348692)

Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)

Type 2 Diabetes, Cortisol Excess Phase 2 Interventional 1,500 participants sought

Texas Valley Clinical Research - Mission, TX — Mission, Texas (4.9 mi) · Sponsor: Sparrow Pharmaceuticals

See eligibility & contact on ClinicalTrials.gov (NCT07296484)

Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children and Adolescents With Short Stature or Growth Failure Due to Growth Hormone Sufficient Disorders

Turner Syndrome, Short Stature Homeobox Gene Mutation Phase 3 Interventional 186 participants sought

Ascendis Pharma Investigational Site — Edinburg, Texas (7.4 mi) · Sponsor: Ascendis Pharma A/S

See eligibility & contact on ClinicalTrials.gov (NCT07221851)

A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight

Overweight, Obesity Phase 3 Interventional 460 participants sought

Texas Valley Clinical Research — Weslaco, Texas (16.5 mi) · Sponsor: Novo Nordisk A/S

See eligibility & contact on ClinicalTrials.gov (NCT07253285)

Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer

Endometrial Cancer, Recurrent or Progressive Endometrial Cancer Phase 3 Interventional 660 participants sought

USOR - Texas Oncology — McAllen, Texas (1.8 mi) · Sponsor: Genmab

See eligibility & contact on ClinicalTrials.gov (NCT07166094)

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

NASH With Fibrosis, MASH With Fibrosis Phase 3 Interventional 1,650 participants sought

Akero Clinical Study Site — McAllen, Texas (1.8 mi) · Sponsor: Akero Therapeutics, Inc

See eligibility & contact on ClinicalTrials.gov (NCT06215716)

Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults

Atopic Dermatitis N/A Observational 1,000 participants sought

Galderma Investigational Site 7062 — Edinburg, Texas (7.4 mi) · Sponsor: Galderma R&D

See eligibility & contact on ClinicalTrials.gov (NCT06988605)

Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers

Diabetic Foot Ulcer N/A Interventional 450 participants sought

Futuro Clinical Trials, LLC — McAllen, Texas (1.8 mi) · Sponsor: Piomic Medical

See eligibility & contact on ClinicalTrials.gov (NCT05758545)

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

Breast Cancer Phase 3 Interventional 4,220 participants sought

Texas Oncology- Central South — Weslaco, Texas (16.5 mi) · Sponsor: Stemline Therapeutics, Inc.

See eligibility & contact on ClinicalTrials.gov (NCT06492616)

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

Breast Neoplasms, Neoplasm Metastasis Phase 3 Interventional 920 participants sought

Nova Oncology — McAllen, Texas (1.8 mi) · Sponsor: Eli Lilly and Company

See eligibility & contact on ClinicalTrials.gov (NCT07174336)

A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C)

Irritable Bowel Syndrome, Constipation Phase 2 Interventional 342 participants sought

Biopharma Informatic, LLC — McAllen, Texas (1.8 mi) · Sponsor: Eli Lilly and Company

See eligibility & contact on ClinicalTrials.gov (NCT07545772)

Pharmacokinetic (PK), Pharmacodynamic (PD) and Tolerability of Osilodrostat in Pediatric Patients With Cushing's Syndrome

Cushing Syndrome Phase 2 Interventional 12 participants sought

Texas Valley Clinical Research — Weslaco, Texas (16.5 mi) · Sponsor: RECORDATI GROUP

See eligibility & contact on ClinicalTrials.gov (NCT03708900)

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

Type 2 Diabetes Phase 2 Interventional 240 participants sought

Texas Valley Clinical Research — Weslaco, Texas (16.5 mi) · Sponsor: Eli Lilly and Company

See eligibility & contact on ClinicalTrials.gov (NCT06897475)

EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease

COVID-19 Phase 3 Interventional 160 participants sought

Biopharma Informatic, LLC — McAllen, Texas (1.8 mi) · Sponsor: Pfizer

See eligibility & contact on ClinicalTrials.gov (NCT05261139)

A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

Relapsing Multiple Sclerosis, Multiple Sclerosis N/A Observational 2,000 participants sought

TG Therapeutics Investigational Trial Site — Edinburg, Texas (7.4 mi) · Sponsor: TG Therapeutics, Inc.

See eligibility & contact on ClinicalTrials.gov (NCT06433752)

A Study to Evaluate the Treatment Outcomes of Subcutaneous Anifrolumab in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus Erythematosus

Systemic Lupus Erythematosus Phase 3 Interventional 245 participants sought

Research Site — Edinburg, Texas (7.4 mi) · Sponsor: AstraZeneca

See eligibility & contact on ClinicalTrials.gov (NCT07430306)

Evaluation of ELU42 Topical Spray for the Treatment of Diabetic Foot Ulcers

Diabetic Foot Ulcer, Wagner Grade 1 - 2 Phase 1, Phase 2 Interventional 15 participants sought

Futuro Clinical Trials — McAllen, Texas (1.8 mi) · Sponsor: Eluciderm Inc

See eligibility & contact on ClinicalTrials.gov (NCT07396376)

Paid Clinical Trials in McAllen, TX

Studies recruiting near McAllen right now

A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy

Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis

Efficacy of Fusidic Acid 1% in the Treatment of Bacterial Conjunctivitis

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)

A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia

A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated

Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)

Lot-to-lot Consistency Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From 2 Months of Age

Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)

Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children and Adolescents With Short Stature or Growth Failure Due to Growth Hormone Sufficient Disorders

A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight

Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults

Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C)

Pharmacokinetic (PK), Pharmacodynamic (PD) and Tolerability of Osilodrostat in Pediatric Patients With Cushing's Syndrome

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease

A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

A Study to Evaluate the Treatment Outcomes of Subcutaneous Anifrolumab in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus Erythematosus

Evaluation of ELU42 Topical Spray for the Treatment of Diabetic Foot Ulcers

Top-rated research centers in McAllen

DHR Health Institute for Research and Development

Rio Grande Valley Clinical Research Institute

Elevate Clinical Research - McAllen

Futuro Clinical Trials, LLC

McAllen Research

Discovery Clinical Trials - Mission

Texas Valley Clinical Research

Clinical trials in McAllen: what's recruiting

How to enroll in a paid study in McAllen

Frequently asked questions

Paid clinical trials near McAllen

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New paid studies open every week