Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/MI/South Lyon
Updated July 2026 from ClinicalTrials.gov

Paid Clinical Trials in South Lyon, MI

Studies commonly pay $75 to $4,500 per completed study

1,315 clinical trials are currently recruiting participants within 30 miles of South Lyon. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

1,315studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near South Lyon right now

Top 25 of 1,315 recruiting studies, sorted by proximity — each links to its official registry page

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

PIK3CA Mutation, HER2- Negative Breast Cancer Phase 3 Interventional 540 participants sought
University of Michigan — Ann Arbor, Michigan (13.5 mi) · Sponsor: Relay Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06982521)

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

Neovascular Age-related Macular Degeneration Phase 4 Interventional 188 participants sought
Associated Retinal Consultants PC — Royal Oak, Michigan (26.0 mi) · Sponsor: Genentech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04853251)

Treatment of the Biceps With Concomitant Supraspinatus Tears

Supraspinatus Tear N/A Interventional 180 participants sought
Sports Medicine and Shoulder Surgery, University of Michigan — Ann Arbor, Michigan (13.5 mi) · Sponsor: La Tour Hospital
See eligibility & contact on ClinicalTrials.gov (NCT05660031)

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

Diffuse Intrinsic Pontine Gliomas (DIPG), Progressive DIPG Phase 2 Interventional 60 participants sought
C.S. Mott Children's Hospital — Ann Arbor, Michigan (13.5 mi) · Sponsor: Nationwide Children's Hospital
See eligibility & contact on ClinicalTrials.gov (NCT06838676)

Prediction Augmented Screening Initiative

Lung Cancer, Lung Cancer Screening N/A Interventional 23,520 participants sought
VA Ann Arbor Healthcare System, Ann Arbor, MI — Ann Arbor, Michigan (13.5 mi) · Sponsor: VA Office of Research and Development
See eligibility & contact on ClinicalTrials.gov (NCT06538636)

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

Metastatic Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma Phase 3 Interventional 1,524 participants sought
Trinity Health Saint Joseph Mercy Hospital Ann Arbor — Ann Arbor, Michigan (13.5 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT07200830)

Phase 2 EL219 Versus Liposomal Amphotericin B or Voriconazole for Early Antifungal Therapy

Invasive Mould Infection Phase 2 Interventional 60 participants sought
U. of Michigan — Ann Arbor, Michigan (13.5 mi) · Sponsor: Elion Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07215273)

Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection

Viral Pneumonia Phase 2 Interventional 550 participants sought
William Beaumont Hospital — Royal Oak, Michigan (26.0 mi) · Sponsor: Synairgen Research Ltd.
See eligibility & contact on ClinicalTrials.gov (NCT06999603)

Study of Momelotinib in Combination With Luspatercept in Participants With Transfusion Dependent Myelofibrosis

Primary Myelofibrosis, Myelofibrosis; Primary Myelofibrosis; Post-polycythemia Vera Myelofibrosis; Post-essential Thrombocythemia Myelofibrosis Phase 2 Interventional 68 participants sought
GSK Investigational Site — Ann Arbor, Michigan (13.5 mi) · Sponsor: GlaxoSmithKline
See eligibility & contact on ClinicalTrials.gov (NCT06517875)

The Vanguard Study: Testing a New Way to Screen for Cancer

Bladder Carcinoma, Breast Carcinoma N/A Interventional 24,000 participants sought
Henry Ford Medical Center-Columbus — Novi, Michigan (9.1 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06995898)

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Recurrent Head and Neck Squamous Cell Carcinoma, Recurrent Hypopharyngeal Squamous Cell Carcinoma Phase 2 Interventional 188 participants sought
University of Michigan Rogel Cancer Center — Ann Arbor, Michigan (13.5 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04671667)

A Study to Learn About the Study Medicine Called Rimegepant in Adolescents With Frequent Migraine

Migraine Phase 3 Interventional 200 participants sought
Michigan Headache & Neurological Institute — Ann Arbor, Michigan (13.5 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT06616194)

Comparison of Uncomplicated Candidemia Therapy Duration in Children

Invasive Candidiasis N/A Interventional 420 participants sought
CS Mott Children's Hospital — Ann Arbor, Michigan (13.5 mi) · Sponsor: Arkansas Children's Hospital Research Institute
See eligibility & contact on ClinicalTrials.gov (NCT05763251)

An Extension Study for Patients Previously Enrolled in Studies With Pelabresib

Hematologic Malignancy, Solid Tumor Phase 3 Interventional 50 participants sought
Uni Of Michigan Health System — Ann Arbor, Michigan (13.5 mi) · Sponsor: Novartis Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT06401356)

A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacabtagene- Autoleucel / Zola-cel), CD19-CAR T Cells, Versus Standard of Care in Participants With Active Systemic Sclerosis

Systemic Sclerosis Phase 3 Interventional 92 participants sought
Local Institution - 0034 — Ann Arbor, Michigan (13.5 mi) · Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
See eligibility & contact on ClinicalTrials.gov (NCT07335562)

Ablation-Index Guided Scar-Mediated Ventricular Tachycardia Ablation in Patients With Ischemic Cardiomyopathy

Ventricular Tachycardia, Ischemic Cardiomyopathy N/A Interventional 100 participants sought
Medical University of Michigan — Ann Arbor, Michigan (13.5 mi) · Sponsor: Rush University Medical Center
See eligibility & contact on ClinicalTrials.gov (NCT06138873)

Advancing Decisions About Virtual Service Encounters

Health Care Costs, Delivery of Health Care N/A Interventional 600 participants sought
VA Ann Arbor Healthcare System, Ann Arbor, MI — Ann Arbor, Michigan (13.5 mi) · Sponsor: VA Office of Research and Development
See eligibility & contact on ClinicalTrials.gov (NCT06539988)
Google-rated

Top-rated research centers in South Lyon

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Detroit Clinical Research Center

★ 5.0
30160 Orchard Lake Rd #110, Farmington Hills, MI 48334
(248) 737-5939

Bolt Clinical Research

609 W Main St, Brighton, MI 48116
(989) 996-0860

Michigan Center of Medical Research

★ 3.0
30160 Orchard Lake Rd #160, Farmington Hills, MI 48334
(248) 747-4383
"Dr Green has lefted the office. If you have medication. You better check up on them. They didn't even tell me till I called them. With a problem. Ex…"
— feather smith, 1★

Michigan Institute for Clinical & Health Research

★ 5.0
1600 Huron Pkwy, Ann Arbor, MI 48105
(734) 998-7474

Quest Research Institute

★ 4.9
28555 Orchard Lake Rd Computer Lab, Farmington Hills, MI 48334
(248) 957-8940
"Grateful for the opportunity to participate in this clinical trial."
— Magra, 5★

Revive Research Institute

★ 3.7
28266 Franklin Rd, Southfield, MI 48034
(248) 721-9539
"Khalida and anitha are the most professional caring healthcare workers i have ever encountered thank you so much for you're patients and you're help …"
— Sara, 5★

DM Clinical Research-Detroit

★ 4.7
20180 W 12 Mile Rd Ste 400, Southfield, MI 48076
(313) 513-1616
"Very friendly very welcoming very nice overall"
— Aidan Nason, 5★

Revival Research Institute

★ 3.7
28270 Franklin Rd, Southfield, MI 48034
(248) 721-9539

Headlands Research Detroit

★ 4.7
29355 Northwestern Hwy #200, Southfield, MI 48034
(248) 243-1870
"Warm, friendly staff - great experience and awesome to work with!"
— Gina Angellotti, 5★

Clinical trials in South Lyon: what's recruiting

The South Lyon area currently has 1,315 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to South Lyon, the most active research areas are:

  • Cancer & Oncology7 studies
  • Heart & Vascular3 studies
  • Liver & Kidney3 studies
  • Immune & Skin1 studies
  • Diabetes & Metabolism1 studies

Every listing shows the study phase, the recruiting site and its distance from South Lyon, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in South Lyon

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

South Lyon participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

Do I need to be sick to join a clinical trial in South Lyon?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Are clinical trials in South Lyon safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in South Lyon, MI?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
What is the difference between a research center and a hospital study in South Lyon?
Dedicated research centers (listed on this page with their Google ratings) run studies as their core business — often healthy-volunteer and vaccine studies with structured compensation. Hospital and university studies tend to focus on patients with specific conditions. Both types are registered and IRB-supervised.
How often do new paid studies open in South Lyon?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of South Lyon.

Paid clinical trials near South Lyon

Other metros within reach

Ann Arbor, MI1,179 Detroit, MI1,179 Flint, MI181 Toledo, OH209 Lansing, MI185 Lorain, OH1,313 Kalamazoo, MI109 Fort Wayne, IN112

More of MI

Detroit1,179 Ann Arbor1,179 Grand Rapids455 Lansing185 Flint181 Kalamazoo109 Muskegon61

New paid studies open every week

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