How much do paid clinical trials in Colorado Springs pay?

Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.

Are clinical trials in Colorado Springs safe?

Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.

How do I join a study in Colorado Springs, CO?

Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.

Is compensation for clinical trials taxable?

In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.

How often do new paid studies open in Colorado Springs?

Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Colorado Springs.

Paid Clinical Trials Colorado Springs, CO — 207 Studies Recruiting (Jul 2026)

Rotator Cuff Repairs With or Without BioEnthesis™ Augmentation

Rotator Cuff Tears, Rotator Cuff Injuries Phase 4 Interventional 100 participants sought

10th Medical Group - Air Force Academy — Air Force Academy, Colorado (10.4 mi) · Sponsor: Brooke Army Medical Center

See eligibility & contact on ClinicalTrials.gov (NCT06289686)

A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy

Geographic Atrophy, Macular Degeneration N/A Observational 500 participants sought

Retina Consultants of Southern Colorado — Colorado Springs, Colorado (4.0 mi) · Sponsor: Astellas Pharma Global Development, Inc.

See eligibility & contact on ClinicalTrials.gov (NCT06779773)

Optimizing Reperfusion to Improve Outcomes and Neurologic Function

Acute Ischemic Stroke Phase 2, Phase 3 Interventional 740 participants sought

Corxel Investigational Site — Colorado Springs, Colorado (4.0 mi) · Sponsor: Corxel Pharmaceuticals

See eligibility & contact on ClinicalTrials.gov (NCT06990867)

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis, Ulcerative Colitis Chronic Phase 2 Interventional 140 participants sought

Peak Gastroenterology Associates — Colorado Springs, Colorado (4.0 mi) · Sponsor: Eli Lilly and Company

See eligibility & contact on ClinicalTrials.gov (NCT06598943)

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Multiple conditions Phase 2 Interventional 150 participants sought

UCHealth Memorial Hospital Central — Colorado Springs, Colorado (4.0 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT05136196)

Improving Care for Rural Patients With Solid Tumors

Lung Cancer, Head and Neck Cancer N/A Interventional 320 participants sought

Memorial Hospital Central — Colorado Springs, Colorado (4.0 mi) · Sponsor: University of Colorado, Denver

See eligibility & contact on ClinicalTrials.gov (NCT04916990)

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

Plasma Cell Myeloma, RISS Stage I Plasma Cell Myeloma Phase 3 Interventional 1,450 participants sought

Penrose-Saint Francis Healthcare — Colorado Springs, Colorado (4.0 mi) · Sponsor: ECOG-ACRIN Cancer Research Group

See eligibility & contact on ClinicalTrials.gov (NCT04566328)

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

Advanced Endometrial Carcinoma, Recurrent Endometrial Carcinoma Phase 3 Interventional 255 participants sought

UCHealth Memorial Hospital Central — Colorado Springs, Colorado (4.0 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT07198074)

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

Moderately to Severely Active Crohns Disease Phase 3 Interventional 425 participants sought

Peak Gastroenterology Associates — Colorado Springs, Colorado (4.0 mi) · Sponsor: Hoffmann-La Roche

See eligibility & contact on ClinicalTrials.gov (NCT06819891)

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma, Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7 Phase 2, Phase 3 Interventional 613 participants sought

Penrose-Saint Francis Healthcare — Colorado Springs, Colorado (4.0 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT01810913)

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Ovarian Carcinoma N/A Interventional 1,956 participants sought

Penrose-Saint Francis Healthcare — Colorado Springs, Colorado (4.0 mi) · Sponsor: NRG Oncology

See eligibility & contact on ClinicalTrials.gov (NCT04251052)

IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

Type B Aortic Dissection N/A Interventional 1,100 participants sought

Memorial Hospital Central — Colorado Springs, Colorado (4.0 mi) · Sponsor: Duke University

See eligibility & contact on ClinicalTrials.gov (NCT06087029)

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

Breast Carcinoma, Colorectal Carcinoma N/A Observational 2,000 participants sought

Penrose-Saint Francis Healthcare — Colorado Springs, Colorado (4.0 mi) · Sponsor: Wake Forest University Health Sciences

See eligibility & contact on ClinicalTrials.gov (NCT06418204)

Terumo Aortic Global Endovascular Registry

Abdominal Aortic Aneurysm, Thoracic Aortic Aneurysm N/A Observational 1,000 participants sought

UC Health Memorial Hospital Center — Colorado Springs, Colorado (4.0 mi) · Sponsor: Vascutek Ltd.

See eligibility & contact on ClinicalTrials.gov (NCT04246463)

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

Castration-Resistant Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8 Phase 2 Interventional 474 participants sought

UCHealth Memorial Hospital Central — Colorado Springs, Colorado (4.0 mi) · Sponsor: Alliance for Clinical Trials in Oncology

See eligibility & contact on ClinicalTrials.gov (NCT06632977)

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)

Psychosis Associated With Alzheimer's Disease Phase 3 Interventional 410 participants sought

Local Institution - 1014 — Colorado Springs, Colorado (4.0 mi) · Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

See eligibility & contact on ClinicalTrials.gov (NCT05511363)

RSSearch Patient Registry-Long Term Study of Use of SRS/SBRT

Neoplasms, Arteriovenous Malformation of Central Nervous System N/A Observational 50,000 participants sought

Penrose Cancer Center — Colorado Springs, Colorado (4.0 mi) · Sponsor: The Radiosurgery Society

See eligibility & contact on ClinicalTrials.gov (NCT01885299)

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

Prostate Cancer (Adenocarcinoma) Phase 3 Interventional 830 participants sought

Penrose-Saint Francis Healthcare — Colorado Springs, Colorado (4.0 mi) · Sponsor: Canadian Cancer Trials Group

See eligibility & contact on ClinicalTrials.gov (NCT06592924)

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

Stage I Breast Cancer Phase 3 Interventional 1,670 participants sought

Penrose-Saint Francis Healthcare — Colorado Springs, Colorado (4.0 mi) · Sponsor: NRG Oncology

See eligibility & contact on ClinicalTrials.gov (NCT04852887)

Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

Breast Cancer, Cognitive Impairments N/A Interventional 386 participants sought

Penrose-Saint Francis Healthcare — Colorado Springs, Colorado (4.0 mi) · Sponsor: NRG Oncology

See eligibility & contact on ClinicalTrials.gov (NCT05896189)

Reducing Asthma Attacks in Disadvantaged School Children With Asthma

Asthma in Children N/A Interventional 300 participants sought

Colorado Springs 11 — Colorado Springs, Colorado (4.0 mi) · Sponsor: University of Colorado, Denver

See eligibility & contact on ClinicalTrials.gov (NCT06003569)

Moderate Aerobic Exercise for Managing Menstrual Cycle Symptoms

Premenstrual Syndrome, Menstrual Cycle N/A Interventional 35 participants sought

William J. Hybl Sports Medicine and Performance Center — Colorado Springs, Colorado (4.0 mi) · Sponsor: University of Colorado, Colorado Springs

See eligibility & contact on ClinicalTrials.gov (NCT07084714)

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

Intracranial Meningioma, Recurrent Meningioma Phase 2 Interventional 124 participants sought

Penrose-Saint Francis Healthcare — Colorado Springs, Colorado (4.0 mi) · Sponsor: Alliance for Clinical Trials in Oncology

See eligibility & contact on ClinicalTrials.gov (NCT02523014)

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

NASH With Fibrosis, MASH With Fibrosis Phase 3 Interventional 1,650 participants sought

Akero Clinical Study Site — Colorado Springs, Colorado (4.0 mi) · Sponsor: Akero Therapeutics, Inc

See eligibility & contact on ClinicalTrials.gov (NCT06215716)

Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

Extensive Stage Lung Small Cell Carcinoma Phase 2, Phase 3 Interventional 138 participants sought

Penrose-Saint Francis Healthcare — Colorado Springs, Colorado (4.0 mi) · Sponsor: National Cancer Institute (NCI)

See eligibility & contact on ClinicalTrials.gov (NCT04402788)

Paid Clinical Trials in Colorado Springs, CO

Studies recruiting near Colorado Springs right now

Rotator Cuff Repairs With or Without BioEnthesis™ Augmentation

A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy

Optimizing Reperfusion to Improve Outcomes and Neurologic Function

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Improving Care for Rural Patients With Solid Tumors

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

Terumo Aortic Global Endovascular Registry

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)

RSSearch Patient Registry-Long Term Study of Use of SRS/SBRT

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

Reducing Asthma Attacks in Disadvantaged School Children With Asthma

Moderate Aerobic Exercise for Managing Menstrual Cycle Symptoms

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

Top-rated research centers in Colorado Springs

Legacy Clinical Trials of Colorado Springs

Skylight Health Research

MCB Clinical Research Centers

Optum - Clinical Research

Lane Center for Academic Health Sciences at UCCS

Lynn Institute of the Rockies

Ascend Clinical

WellLife Medical Centers

Delta Waves

Clinical trials in Colorado Springs: what's recruiting

How to enroll in a paid study in Colorado Springs

Frequently asked questions

Paid clinical trials near Colorado Springs

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